Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018655835> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2018655835 endingPage "223" @default.
- W2018655835 startingPage "211" @default.
- W2018655835 abstract "Folates are important cofactors in the transfer and utilization of one-carbon-groups and play a key role in the remethylation of methionine thus providing essential methyl groups for numerous biological reactions. Furthermore, folates donate one-carbon units in the process of DNA-biosynthesis with implications for the regulation of gene expression, transcription, chromatine structure, genomic repair and genomic stability. As the role of folate deficiency in atherosclerotic cardiovascular disease, neurological and neuropsychiatric disorders, in congenital defects and carcinogenesis has become better understood, folate has been recognized as having great potential to prevent these many disorders through folate supplementation for the general population. Folate acts directly to produce antioxidant effects, interactions with enzyme endothelial NO synthase (eNOS) and effects on cofactor bioavailability of NO. Folate acts indirectly to lower homocysteine levels and insure optimal functioning of the methylation cycle. Folate metabolism provides an interesting example of gene-environmental interaction. A great part of the population, especially subgroups with higher demand, appears to have suboptimal folate intake, as determined through more sensitive parameters now widely determined. The available data strongly suggest that criteria for folate deficiency may have to be redefined." @default.
- W2018655835 created "2016-06-24" @default.
- W2018655835 creator A5027522449 @default.
- W2018655835 date "2002-04-01" @default.
- W2018655835 modified "2023-09-30" @default.
- W2018655835 title "Physiology of Folic Acid in Health and Disease" @default.
- W2018655835 doi "https://doi.org/10.2174/1389200024605163" @default.
- W2018655835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12003352" @default.
- W2018655835 hasPublicationYear "2002" @default.
- W2018655835 type Work @default.
- W2018655835 sameAs 2018655835 @default.
- W2018655835 citedByCount "144" @default.
- W2018655835 countsByYear W20186558352012 @default.
- W2018655835 countsByYear W20186558352013 @default.
- W2018655835 countsByYear W20186558352014 @default.
- W2018655835 countsByYear W20186558352015 @default.
- W2018655835 countsByYear W20186558352016 @default.
- W2018655835 countsByYear W20186558352017 @default.
- W2018655835 countsByYear W20186558352018 @default.
- W2018655835 countsByYear W20186558352019 @default.
- W2018655835 countsByYear W20186558352020 @default.
- W2018655835 countsByYear W20186558352021 @default.
- W2018655835 countsByYear W20186558352022 @default.
- W2018655835 countsByYear W20186558352023 @default.
- W2018655835 crossrefType "journal-article" @default.
- W2018655835 hasAuthorship W2018655835A5027522449 @default.
- W2018655835 hasConcept C126322002 @default.
- W2018655835 hasConcept C2777090595 @default.
- W2018655835 hasConcept C2779134260 @default.
- W2018655835 hasConcept C2780841255 @default.
- W2018655835 hasConcept C2780912031 @default.
- W2018655835 hasConcept C2908647359 @default.
- W2018655835 hasConcept C515207424 @default.
- W2018655835 hasConcept C54355233 @default.
- W2018655835 hasConcept C55493867 @default.
- W2018655835 hasConcept C71924100 @default.
- W2018655835 hasConcept C80315684 @default.
- W2018655835 hasConcept C86803240 @default.
- W2018655835 hasConcept C99454951 @default.
- W2018655835 hasConceptScore W2018655835C126322002 @default.
- W2018655835 hasConceptScore W2018655835C2777090595 @default.
- W2018655835 hasConceptScore W2018655835C2779134260 @default.
- W2018655835 hasConceptScore W2018655835C2780841255 @default.
- W2018655835 hasConceptScore W2018655835C2780912031 @default.
- W2018655835 hasConceptScore W2018655835C2908647359 @default.
- W2018655835 hasConceptScore W2018655835C515207424 @default.
- W2018655835 hasConceptScore W2018655835C54355233 @default.
- W2018655835 hasConceptScore W2018655835C55493867 @default.
- W2018655835 hasConceptScore W2018655835C71924100 @default.
- W2018655835 hasConceptScore W2018655835C80315684 @default.
- W2018655835 hasConceptScore W2018655835C86803240 @default.
- W2018655835 hasConceptScore W2018655835C99454951 @default.
- W2018655835 hasIssue "2" @default.
- W2018655835 hasLocation W20186558351 @default.
- W2018655835 hasLocation W20186558352 @default.
- W2018655835 hasOpenAccess W2018655835 @default.
- W2018655835 hasPrimaryLocation W20186558351 @default.
- W2018655835 hasRelatedWork W1551144656 @default.
- W2018655835 hasRelatedWork W1563841371 @default.
- W2018655835 hasRelatedWork W162348252 @default.
- W2018655835 hasRelatedWork W1966997650 @default.
- W2018655835 hasRelatedWork W2059528324 @default.
- W2018655835 hasRelatedWork W2068463312 @default.
- W2018655835 hasRelatedWork W2084325772 @default.
- W2018655835 hasRelatedWork W2170373468 @default.
- W2018655835 hasRelatedWork W2316762502 @default.
- W2018655835 hasRelatedWork W751754529 @default.
- W2018655835 hasVolume "3" @default.
- W2018655835 isParatext "false" @default.
- W2018655835 isRetracted "false" @default.
- W2018655835 magId "2018655835" @default.
- W2018655835 workType "article" @default.