FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018665575> ?p ?o ?g. }

• W2018665575 endingPage "637" @default.
• W2018665575 startingPage "628" @default.
• W2018665575 abstract "This study examined the effect of posttraumatic hypoxia on cerebral vascular responsivity and axonal damage, while also exploring hypothermia's potential to attenuate these responses. Rats were subjected to impact acceleration injury (IAI) and equipped with cranial windows to assess vascular reactivity to topical acetylcholine, with postmortem analyses using antibodies to amyloid precursor protein to assess axonal damage. Animals were subjected to hypoxia alone, IAI and hypoxia, IAI and hypoxia before induction of moderate hypothermia (33 degrees C), IAI and hypoxia induced during hypothermic intervention, and IAI and hypoxia initiated after hypothermia. Hypoxia alone had no impact on vascular reactivity or axonal damage. Acceleration injury and posttraumatic hypoxia resulted in dramatic axonal damage and altered vascular reactivity. When IAI and hypoxia were followed by hypothermic intervention, no axonal or vascular protection ensued. However, when IAI was followed by hypoxia induced during hypothermia, axonal and vascular protection followed. When this same hypoxic insult followed the use of hypothermia, no benefit ensued. These studies show that early hypoxia and delayed hypoxia exert damaging axonal and vascular consequences. Although this damage is attenuated by hypothermia, this follows only when hypoxia occurs during hypothermia, with no benefit found if the hypoxic insult proceeds or follows hypothermia." @default.
• W2018665575 created "2016-06-24" @default.
• W2018665575 creator A5019443322 @default.
• W2018665575 creator A5023360077 @default.
• W2018665575 creator A5029614784 @default.
• W2018665575 creator A5047497420 @default.
• W2018665575 date "2009-11-11" @default.
• W2018665575 modified "2023-10-02" @default.
• W2018665575 title "The Adverse Pial Arteriolar and Axonal Consequences of Traumatic Brain Injury Complicated by Hypoxia and Their Therapeutic Modulation with Hypothermia in Rat" @default.
• W2018665575 cites W144748642 @default.
• W2018665575 cites W1965747189 @default.
• W2018665575 cites W1968743968 @default.
• W2018665575 cites W1970451322 @default.
• W2018665575 cites W1972966488 @default.
• W2018665575 cites W1973701462 @default.
• W2018665575 cites W1975498366 @default.
• W2018665575 cites W1981082943 @default.
• W2018665575 cites W1984400181 @default.
• W2018665575 cites W1986240693 @default.
• W2018665575 cites W1989488293 @default.
• W2018665575 cites W2002843252 @default.
• W2018665575 cites W2005573071 @default.
• W2018665575 cites W2006531563 @default.
• W2018665575 cites W2007743087 @default.
• W2018665575 cites W2014019081 @default.
• W2018665575 cites W2015901005 @default.
• W2018665575 cites W2016246099 @default.
• W2018665575 cites W2018867075 @default.
• W2018665575 cites W2020385862 @default.
• W2018665575 cites W2025164911 @default.
• W2018665575 cites W2030118453 @default.
• W2018665575 cites W2041190532 @default.
• W2018665575 cites W2043112205 @default.
• W2018665575 cites W2077327351 @default.
• W2018665575 cites W2078797826 @default.
• W2018665575 cites W2082851412 @default.
• W2018665575 cites W2086353424 @default.
• W2018665575 cites W2090665941 @default.
• W2018665575 cites W2103044571 @default.
• W2018665575 cites W2113965122 @default.
• W2018665575 cites W2121462621 @default.
• W2018665575 cites W2136873903 @default.
• W2018665575 cites W2159374531 @default.
• W2018665575 cites W3192915170 @default.
• W2018665575 cites W4293586670 @default.
• W2018665575 doi "https://doi.org/10.1038/jcbfm.2009.235" @default.
• W2018665575 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2949135" @default.
• W2018665575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19904286" @default.
• W2018665575 hasPublicationYear "2009" @default.
• W2018665575 type Work @default.
• W2018665575 sameAs 2018665575 @default.
• W2018665575 citedByCount "31" @default.
• W2018665575 countsByYear W20186655752012 @default.
• W2018665575 countsByYear W20186655752013 @default.
• W2018665575 countsByYear W20186655752014 @default.
• W2018665575 countsByYear W20186655752015 @default.
• W2018665575 countsByYear W20186655752016 @default.
• W2018665575 countsByYear W20186655752017 @default.
• W2018665575 countsByYear W20186655752018 @default.
• W2018665575 countsByYear W20186655752019 @default.
• W2018665575 countsByYear W20186655752021 @default.
• W2018665575 countsByYear W20186655752023 @default.
• W2018665575 crossrefType "journal-article" @default.
• W2018665575 hasAuthorship W2018665575A5019443322 @default.
• W2018665575 hasAuthorship W2018665575A5023360077 @default.
• W2018665575 hasAuthorship W2018665575A5029614784 @default.
• W2018665575 hasAuthorship W2018665575A5047497420 @default.
• W2018665575 hasBestOaLocation W20186655751 @default.
• W2018665575 hasConcept C118552586 @default.
• W2018665575 hasConcept C126322002 @default.
• W2018665575 hasConcept C178790620 @default.
• W2018665575 hasConcept C185592680 @default.
• W2018665575 hasConcept C2777390192 @default.
• W2018665575 hasConcept C2781017439 @default.
• W2018665575 hasConcept C2781458332 @default.
• W2018665575 hasConcept C42219234 @default.
• W2018665575 hasConcept C540031477 @default.
• W2018665575 hasConcept C71924100 @default.
• W2018665575 hasConcept C7836513 @default.
• W2018665575 hasConceptScore W2018665575C118552586 @default.
• W2018665575 hasConceptScore W2018665575C126322002 @default.
• W2018665575 hasConceptScore W2018665575C178790620 @default.
• W2018665575 hasConceptScore W2018665575C185592680 @default.
• W2018665575 hasConceptScore W2018665575C2777390192 @default.
• W2018665575 hasConceptScore W2018665575C2781017439 @default.
• W2018665575 hasConceptScore W2018665575C2781458332 @default.
• W2018665575 hasConceptScore W2018665575C42219234 @default.
• W2018665575 hasConceptScore W2018665575C540031477 @default.
• W2018665575 hasConceptScore W2018665575C71924100 @default.
• W2018665575 hasConceptScore W2018665575C7836513 @default.
• W2018665575 hasIssue "3" @default.
• W2018665575 hasLocation W20186655751 @default.
• W2018665575 hasLocation W20186655752 @default.
• W2018665575 hasLocation W20186655753 @default.
• W2018665575 hasLocation W20186655754 @default.
• W2018665575 hasOpenAccess W2018665575 @default.
• W2018665575 hasPrimaryLocation W20186655751 @default.
• W2018665575 hasRelatedWork W1585466145 @default.

• next