FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018670493> ?p ?o ?g. }

• W2018670493 endingPage "e124" @default.
• W2018670493 startingPage "e124" @default.
• W2018670493 abstract "To explore the higher order structure of transcribable chromatin in vivo, its local configuration was assessed through the accessibility of the chromatin to crosslinking with formaldehyde. The application of crosslinked and mildly sheared chromatin to sedimentation velocity centrifugation followed by size-fractionation of the DNA enabled us to biochemically distinguish between chromatin with heavily versus sparsely crosslinkable structures. The separated fractions showed a good correlation with gene expression profiles. Genes with poor crosslinking around the promoter region were actively transcribed, while transcripts were hardly detected from genes with extensive crosslinking in their promoter regions. For the inducible gene, Il2, the distribution of the promoter shifted in the gradient following T-cell receptor stimulation, consistent with a change in structure at this locus during activation. The kinetics of this switch preceded the chromatin change observed in a DNase I accessibility assay. Thus, this new chromatin fractionation technique has revealed a change in chromatin structure that has not been previously characterized." @default.
• W2018670493 created "2016-06-24" @default.
• W2018670493 creator A5003990311 @default.
• W2018670493 creator A5006527692 @default.
• W2018670493 creator A5045114573 @default.
• W2018670493 date "2010-04-05" @default.
• W2018670493 modified "2023-10-03" @default.
• W2018670493 title "A new fractionation assay, based on the size of formaldehyde-crosslinked, mildly sheared chromatin, delineates the chromatin structure at promoter regions" @default.
• W2018670493 cites W1122494316 @default.
• W2018670493 cites W1564804005 @default.
• W2018670493 cites W1601683150 @default.
• W2018670493 cites W1892261914 @default.
• W2018670493 cites W1989542509 @default.
• W2018670493 cites W1993570130 @default.
• W2018670493 cites W2017507606 @default.
• W2018670493 cites W2027061907 @default.
• W2018670493 cites W2035404043 @default.
• W2018670493 cites W2052842503 @default.
• W2018670493 cites W2058306877 @default.
• W2018670493 cites W2066185444 @default.
• W2018670493 cites W2069545688 @default.
• W2018670493 cites W2073869073 @default.
• W2018670493 cites W2093158813 @default.
• W2018670493 cites W2097778167 @default.
• W2018670493 cites W2109829378 @default.
• W2018670493 cites W2130620816 @default.
• W2018670493 cites W2134193463 @default.
• W2018670493 cites W2143142222 @default.
• W2018670493 cites W2144792857 @default.
• W2018670493 cites W2147701937 @default.
• W2018670493 cites W2151553287 @default.
• W2018670493 cites W2164935229 @default.
• W2018670493 doi "https://doi.org/10.1093/nar/gkq203" @default.
• W2018670493 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2887976" @default.
• W2018670493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20371521" @default.
• W2018670493 hasPublicationYear "2010" @default.
• W2018670493 type Work @default.
• W2018670493 sameAs 2018670493 @default.
• W2018670493 citedByCount "11" @default.
• W2018670493 countsByYear W20186704932012 @default.
• W2018670493 countsByYear W20186704932014 @default.
• W2018670493 countsByYear W20186704932015 @default.
• W2018670493 countsByYear W20186704932017 @default.
• W2018670493 countsByYear W20186704932019 @default.
• W2018670493 countsByYear W20186704932021 @default.
• W2018670493 crossrefType "journal-article" @default.
• W2018670493 hasAuthorship W2018670493A5003990311 @default.
• W2018670493 hasAuthorship W2018670493A5006527692 @default.
• W2018670493 hasAuthorship W2018670493A5045114573 @default.
• W2018670493 hasBestOaLocation W20186704931 @default.
• W2018670493 hasConcept C104317684 @default.
• W2018670493 hasConcept C12554922 @default.
• W2018670493 hasConcept C153911025 @default.
• W2018670493 hasConcept C167227067 @default.
• W2018670493 hasConcept C181199279 @default.
• W2018670493 hasConcept C185592680 @default.
• W2018670493 hasConcept C27239569 @default.
• W2018670493 hasConcept C2779377703 @default.
• W2018670493 hasConcept C3017666073 @default.
• W2018670493 hasConcept C43617362 @default.
• W2018670493 hasConcept C54355233 @default.
• W2018670493 hasConcept C552990157 @default.
• W2018670493 hasConcept C55493867 @default.
• W2018670493 hasConcept C67258246 @default.
• W2018670493 hasConcept C83640560 @default.
• W2018670493 hasConcept C86803240 @default.
• W2018670493 hasConcept C95444343 @default.
• W2018670493 hasConcept C97428945 @default.
• W2018670493 hasConceptScore W2018670493C104317684 @default.
• W2018670493 hasConceptScore W2018670493C12554922 @default.
• W2018670493 hasConceptScore W2018670493C153911025 @default.
• W2018670493 hasConceptScore W2018670493C167227067 @default.
• W2018670493 hasConceptScore W2018670493C181199279 @default.
• W2018670493 hasConceptScore W2018670493C185592680 @default.
• W2018670493 hasConceptScore W2018670493C27239569 @default.
• W2018670493 hasConceptScore W2018670493C2779377703 @default.
• W2018670493 hasConceptScore W2018670493C3017666073 @default.
• W2018670493 hasConceptScore W2018670493C43617362 @default.
• W2018670493 hasConceptScore W2018670493C54355233 @default.
• W2018670493 hasConceptScore W2018670493C552990157 @default.
• W2018670493 hasConceptScore W2018670493C55493867 @default.
• W2018670493 hasConceptScore W2018670493C67258246 @default.
• W2018670493 hasConceptScore W2018670493C83640560 @default.
• W2018670493 hasConceptScore W2018670493C86803240 @default.
• W2018670493 hasConceptScore W2018670493C95444343 @default.
• W2018670493 hasConceptScore W2018670493C97428945 @default.
• W2018670493 hasIssue "11" @default.
• W2018670493 hasLocation W20186704931 @default.
• W2018670493 hasLocation W20186704932 @default.
• W2018670493 hasLocation W20186704933 @default.
• W2018670493 hasLocation W20186704934 @default.
• W2018670493 hasOpenAccess W2018670493 @default.
• W2018670493 hasPrimaryLocation W20186704931 @default.
• W2018670493 hasRelatedWork W1965505038 @default.
• W2018670493 hasRelatedWork W2015146829 @default.
• W2018670493 hasRelatedWork W2018670493 @default.
• W2018670493 hasRelatedWork W2034544470 @default.
• W2018670493 hasRelatedWork W2080944064 @default.

• next