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- W2018671 abstract "espanolIntroduccion y objetivos: La eficacia de la administracion conjunta de suero salino isotonico y N-acetilcis-teina presenta resultados dispares en la prevencion de la nefropatia por contraste yodado. Nuestro objetivo fue valorar la posible eficacia de esta estrategia combinada en pacientes con alto riesgo de desarrollar nefropatia inducida por contraste, ingresados y sometidos a intervencionismo coronario percutaneo por sindrome coronario agudo sin elevacion del segmento ST en nuestro centro. Metodo: Se aplico esta estrategia en los pacientes referidos, con al menos un factor de alto riesgo para desarrollar la nefropatia inducida por contraste: mayores de 80 anos, diabetes mellitus, creatinina basal mayor de 1,5 mg/dl o alto volumen de contraste (mayor de 400 ml). El protocolo se aplico durante 12 meses (pacientes que recibieron el protocolo de prevencion) y se comparo con similares pacientes en los 12 meses previos que no recibieron profilaxis. Re-sultados: Un total de 30 pacientes (24 %) desarrollaron nefropatia inducida por contraste. El porcentaje fue significativamente mayor en el grupo que no recibio profilaxis: 35,9 % vs. 11,5 % (p=0.003). Conclusio-nes: La combinacion de N-acetilcisteina por via oral e hidratacion parenteral en pacientes de alto riesgo, con sindrome coronario agudo sin elevacion de ST, podria ser beneficiosa para evitar la aparicion de la nefropatia inducida por contraste. EnglishIntroduction and objectives: The effectiveness of the administration of isotonic saline solution and N-acetyl-cysteine shows different results in the prevention of iodine contrast nephropathy. Our objective was to assess the potential effectiveness of this combined strategy in patients at high risk for contrast-induced nephropathy, who were admitted in our center for percutaneous coronary intervention due to non-ST-segment elevation acute coronary syndrome. Method: This strategy was applied in the patients mentioned, with at least one risk factor for developing contrast-induced nephropathy: over 80 years, diabetes mellitus, baseline creatinine greater than 1.5 mg/dl or high volume of contrast (greater than 400 ml). The protocol was applied for 12 months (patients that received the prevention protocol) and compared with similar patients in the previous 12 months who received no prophy-laxis. Results: A total of 30 patients (24%) developed contrast-induced nephropathy. The percentage was significantly higher in the group that did not receive pro-phylaxis: 35.9% vs. 11.5% (p=0.003). Conclusions: The combination of N-acetylcysteine orally and parenteral hydration in high-risk patients with acute coronary syndrome without ST elevation could be beneficial to avoid the appearance of contrast-induced nephropathy." @default.
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- W2018671 date "2012-01-01" @default.
- W2018671 modified "2023-09-24" @default.
- W2018671 title "Profilaxis de la nefropatía inducida por contraste en pacientes de alto riesgo con síndrome coronario agudo sin elevación del segmento ST" @default.
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