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- W2018673500 abstract "Abstract The immune and nervous systems have various common features in their functional characteristics. Both have an intricate network of synaptic connections and an exquisite communication system that enables intercellular signal transduction. Semaphorins were originally identified as guidance factors for developing neuronal axons. However, accumulating evidence indicates that several semaphorins called “immune semaphorins” are crucial for various phases of immune responses, from the initiation to the termination of inflammatory processes. Furthermore, it is becoming clear that immune semaphorins contribute to pathological immune responses in the central nervous system. Here, we review the present knowledge of the function of semphorins and their receptors in the immune system, and their involvement in the pathogenesis of neurological diseases. (Clin. Exp. Neuroimmunol. doi: 10.1111/j.1759-1961.2009.00004.x, January 2010)" @default.
- W2018673500 created "2016-06-24" @default.
- W2018673500 creator A5004735790 @default.
- W2018673500 creator A5026633755 @default.
- W2018673500 date "2010-01-01" @default.
- W2018673500 modified "2023-10-14" @default.
- W2018673500 title "Involvement of semaphorins and their receptors in neurological diseases" @default.
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- W2018673500 doi "https://doi.org/10.1111/j.1759-1961.2009.00004.x" @default.
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