Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018677130> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2018677130 endingPage "594" @default.
- W2018677130 startingPage "594" @default.
- W2018677130 abstract "A technique for assessing suppressor cell activity in peripheral blood of healthy premature neonates was established using ConA induced suppression of the PHA response in vitro. Neonatal lymphocytes were separated in routine fashion and placed in preculture with ConA (1μg/ml). Cells were also precultured without ConA to provide information on spontaneous suppressor cell activity. After 48 hours incubation, cells were collected, washed and irradiated with 3000r. Effect of precultured cells on PHA stimulated blastogenesis was studied by microculture technique using 105 inactivated cells and an equal number of fresh, autologous lymphocytes (responder cells). Controls were provided by addition of PHA to responder cells alone. Normal adult cells were used for comparison cultures. Data were expressed as one minus the ratio (× 100) of the observed mean cpm of the precultured plus fresh cell blastogenic response to the observed mean cpm of the neonatal control response. Preculture of neonatal lymphocytes yielded suppression in the majority of samples, 73% (mean 33 ± 24) with and 55% (mean 23 ± 15) without ConA; conversely, stimulation was seen in 18% and 27% respectively. Adult studies showed suppression in 25%, unchanged by ConA, but showed stimulation in 50% (mean 45 ± 35) with and 58% (mean 35 ± 25) without ConA. We conclude that neonatal lymphocytes, as studied in this system, demonstrate a propensity to suppress PHA induced blastogenesis." @default.
- W2018677130 created "2016-06-24" @default.
- W2018677130 creator A5009507424 @default.
- W2018677130 creator A5014506920 @default.
- W2018677130 creator A5028740151 @default.
- W2018677130 date "1981-04-01" @default.
- W2018677130 modified "2023-09-26" @default.
- W2018677130 title "908 SUPPRESSOR CELL ACTIVITY IN NEONATAL PERIPHERAL BLOOD" @default.
- W2018677130 doi "https://doi.org/10.1203/00006450-198104001-00933" @default.
- W2018677130 hasPublicationYear "1981" @default.
- W2018677130 type Work @default.
- W2018677130 sameAs 2018677130 @default.
- W2018677130 citedByCount "0" @default.
- W2018677130 crossrefType "journal-article" @default.
- W2018677130 hasAuthorship W2018677130A5009507424 @default.
- W2018677130 hasAuthorship W2018677130A5014506920 @default.
- W2018677130 hasAuthorship W2018677130A5028740151 @default.
- W2018677130 hasBestOaLocation W20186771301 @default.
- W2018677130 hasConcept C121608353 @default.
- W2018677130 hasConcept C126322002 @default.
- W2018677130 hasConcept C134018914 @default.
- W2018677130 hasConcept C1491633281 @default.
- W2018677130 hasConcept C16685009 @default.
- W2018677130 hasConcept C179185449 @default.
- W2018677130 hasConcept C19869320 @default.
- W2018677130 hasConcept C202751555 @default.
- W2018677130 hasConcept C203014093 @default.
- W2018677130 hasConcept C24998067 @default.
- W2018677130 hasConcept C25642318 @default.
- W2018677130 hasConcept C3017910909 @default.
- W2018677130 hasConcept C49377226 @default.
- W2018677130 hasConcept C55493867 @default.
- W2018677130 hasConcept C71924100 @default.
- W2018677130 hasConcept C86803240 @default.
- W2018677130 hasConceptScore W2018677130C121608353 @default.
- W2018677130 hasConceptScore W2018677130C126322002 @default.
- W2018677130 hasConceptScore W2018677130C134018914 @default.
- W2018677130 hasConceptScore W2018677130C1491633281 @default.
- W2018677130 hasConceptScore W2018677130C16685009 @default.
- W2018677130 hasConceptScore W2018677130C179185449 @default.
- W2018677130 hasConceptScore W2018677130C19869320 @default.
- W2018677130 hasConceptScore W2018677130C202751555 @default.
- W2018677130 hasConceptScore W2018677130C203014093 @default.
- W2018677130 hasConceptScore W2018677130C24998067 @default.
- W2018677130 hasConceptScore W2018677130C25642318 @default.
- W2018677130 hasConceptScore W2018677130C3017910909 @default.
- W2018677130 hasConceptScore W2018677130C49377226 @default.
- W2018677130 hasConceptScore W2018677130C55493867 @default.
- W2018677130 hasConceptScore W2018677130C71924100 @default.
- W2018677130 hasConceptScore W2018677130C86803240 @default.
- W2018677130 hasLocation W20186771301 @default.
- W2018677130 hasOpenAccess W2018677130 @default.
- W2018677130 hasPrimaryLocation W20186771301 @default.
- W2018677130 hasRelatedWork W1983692521 @default.
- W2018677130 hasRelatedWork W1984619393 @default.
- W2018677130 hasRelatedWork W2034768996 @default.
- W2018677130 hasRelatedWork W2054992011 @default.
- W2018677130 hasRelatedWork W2064416809 @default.
- W2018677130 hasRelatedWork W2094599830 @default.
- W2018677130 hasRelatedWork W215531351 @default.
- W2018677130 hasRelatedWork W2406369390 @default.
- W2018677130 hasRelatedWork W2912051024 @default.
- W2018677130 hasRelatedWork W1996741910 @default.
- W2018677130 hasVolume "15" @default.
- W2018677130 isParatext "false" @default.
- W2018677130 isRetracted "false" @default.
- W2018677130 magId "2018677130" @default.
- W2018677130 workType "article" @default.