FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018688488> ?p ?o ?g. }

• W2018688488 abstract "Fungal infections by molds like Aspergillus fumigatus are an increasing health problem which can be fatal in immuno-compromised patients. In healthy individuals, these infections are easily eliminated by the innate and acquired immune system. Complement factor 3 (C3) has a key place within the complement cascade and C3 RNA expression can therefore be used to monitor an impending immune response. Employing a liver cell line (HepG2) as a model system, we have examined their responses to A. fumigatus or beta-glucan, a major component of the fungal wall. C3 RNA expression was increased after stimulation with both LPS and A. fumigatus as well as after incubation with beta-glucan, although with different kinetics. C3 protein release into the supernatant followed an inverse bell-shaped curve when cells were incubated with A. fumigatus or beta-glucan while during LPS stimulation, the release was more stable. HepG2 cells also express Toll-like receptors (TLRs) and both for TLR2 and TLR4, an expression increase was found. These data demonstrate that liver cells are able to react specifically to a fungal pathogen without the help of Kupffer cells." @default.
• W2018688488 created "2016-06-24" @default.
• W2018688488 creator A5005612728 @default.
• W2018688488 creator A5070724204 @default.
• W2018688488 creator A5082764912 @default.
• W2018688488 date "2004-08-01" @default.
• W2018688488 modified "2023-09-27" @default.
• W2018688488 title "Liver cells respond to Aspergillus fumigatus with an increase in C3 secretion and C3 gene expression as well as an expression increase in TLR2 and TLR4" @default.
• W2018688488 cites W1483162601 @default.
• W2018688488 cites W1503620318 @default.
• W2018688488 cites W1707914104 @default.
• W2018688488 cites W1916287332 @default.
• W2018688488 cites W1934547580 @default.
• W2018688488 cites W1935733700 @default.
• W2018688488 cites W1979684449 @default.
• W2018688488 cites W1985966685 @default.
• W2018688488 cites W1992075095 @default.
• W2018688488 cites W1992941967 @default.
• W2018688488 cites W1996736315 @default.
• W2018688488 cites W1998551407 @default.
• W2018688488 cites W2004128152 @default.
• W2018688488 cites W2005998335 @default.
• W2018688488 cites W2010682360 @default.
• W2018688488 cites W2016936846 @default.
• W2018688488 cites W2032282478 @default.
• W2018688488 cites W2054510746 @default.
• W2018688488 cites W2059507666 @default.
• W2018688488 cites W2076498636 @default.
• W2018688488 cites W2092666893 @default.
• W2018688488 cites W2096989812 @default.
• W2018688488 cites W2123215432 @default.
• W2018688488 cites W2130007331 @default.
• W2018688488 cites W2138102959 @default.
• W2018688488 cites W2153911335 @default.
• W2018688488 cites W2164479064 @default.
• W2018688488 cites W2166078611 @default.
• W2018688488 cites W2316502081 @default.
• W2018688488 cites W2406600528 @default.
• W2018688488 cites W2418761918 @default.
• W2018688488 cites W2419625238 @default.
• W2018688488 cites W2436570491 @default.
• W2018688488 doi "https://doi.org/10.1016/j.imlet.2004.05.019" @default.
• W2018688488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15325794" @default.
• W2018688488 hasPublicationYear "2004" @default.
• W2018688488 type Work @default.
• W2018688488 sameAs 2018688488 @default.
• W2018688488 citedByCount "9" @default.
• W2018688488 countsByYear W20186884882012 @default.
• W2018688488 countsByYear W20186884882013 @default.
• W2018688488 crossrefType "journal-article" @default.
• W2018688488 hasAuthorship W2018688488A5005612728 @default.
• W2018688488 hasAuthorship W2018688488A5070724204 @default.
• W2018688488 hasAuthorship W2018688488A5082764912 @default.
• W2018688488 hasConcept C104317684 @default.
• W2018688488 hasConcept C111684460 @default.
• W2018688488 hasConcept C136449434 @default.
• W2018688488 hasConcept C150194340 @default.
• W2018688488 hasConcept C203014093 @default.
• W2018688488 hasConcept C2776070231 @default.
• W2018688488 hasConcept C2776391196 @default.
• W2018688488 hasConcept C2776709828 @default.
• W2018688488 hasConcept C2779787849 @default.
• W2018688488 hasConcept C2781236682 @default.
• W2018688488 hasConcept C49039625 @default.
• W2018688488 hasConcept C55493867 @default.
• W2018688488 hasConcept C86803240 @default.
• W2018688488 hasConcept C8891405 @default.
• W2018688488 hasConcept C89423630 @default.
• W2018688488 hasConceptScore W2018688488C104317684 @default.
• W2018688488 hasConceptScore W2018688488C111684460 @default.
• W2018688488 hasConceptScore W2018688488C136449434 @default.
• W2018688488 hasConceptScore W2018688488C150194340 @default.
• W2018688488 hasConceptScore W2018688488C203014093 @default.
• W2018688488 hasConceptScore W2018688488C2776070231 @default.
• W2018688488 hasConceptScore W2018688488C2776391196 @default.
• W2018688488 hasConceptScore W2018688488C2776709828 @default.
• W2018688488 hasConceptScore W2018688488C2779787849 @default.
• W2018688488 hasConceptScore W2018688488C2781236682 @default.
• W2018688488 hasConceptScore W2018688488C49039625 @default.
• W2018688488 hasConceptScore W2018688488C55493867 @default.
• W2018688488 hasConceptScore W2018688488C86803240 @default.
• W2018688488 hasConceptScore W2018688488C8891405 @default.
• W2018688488 hasConceptScore W2018688488C89423630 @default.
• W2018688488 hasLocation W20186884881 @default.
• W2018688488 hasLocation W20186884882 @default.
• W2018688488 hasOpenAccess W2018688488 @default.
• W2018688488 hasPrimaryLocation W20186884881 @default.
• W2018688488 hasRelatedWork W1517608889 @default.
• W2018688488 hasRelatedWork W1572272884 @default.
• W2018688488 hasRelatedWork W1914689199 @default.
• W2018688488 hasRelatedWork W2018688488 @default.
• W2018688488 hasRelatedWork W2033318041 @default.
• W2018688488 hasRelatedWork W2054605333 @default.
• W2018688488 hasRelatedWork W2098596185 @default.
• W2018688488 hasRelatedWork W2147344665 @default.
• W2018688488 hasRelatedWork W3030153026 @default.
• W2018688488 hasRelatedWork W3209460650 @default.
• W2018688488 isParatext "false" @default.
• W2018688488 isRetracted "false" @default.
• W2018688488 magId "2018688488" @default.

• next