Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018705190> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2018705190 abstract "Abstract Male rats were treated with either 1.14 or 4.56 mg/kg/day of nicotine alkaloid in the drinking water for 34 weeks. Half of each group and an equal number of untreated controls were then exposed to 6% oxygen at 23°C for 12 hours. Immediately after the hypoxia, and at intervals thereafter, hematocrits were measured, the hearts were examined for lesions and assayed for glucose-6-phosphate dehydrogenase (G-6-PDH), isocitric dehydrogenase linked to nicotinamide adenine dinucleotide phosphate (ICDH-NADP), and lactic dehydrogenase (LDH) isoenzyme activities in the soluble fraction of heart homogenate; and for acid phosphatase (AP) and β-glucuronidase (β-G) in the soluble and particulate fractions. No effects were observed on the hematocrits. Treatment with the larger dose of nicotine increased ICDH-NADP and particulate AP activities, and decreased soluble β-G activity. Hypoxia elevated activities of G-6-PDH, LDH5, particulate AP, and both soluble and particulate β-G. Mortality during hypoxia was increased by pretreatment with the larger dose of nicotine. The regression of hypoxic heart lesions became highly variable following nicotine pretreatment. Pretreatment with nicotine also reduced the effect of hypoxia on β-G activity and altered some effects of hypoxia on LDH isoenzymes. The possible significance of these interactions is discussed." @default.
- W2018705190 created "2016-06-24" @default.
- W2018705190 creator A5000505165 @default.
- W2018705190 creator A5050317257 @default.
- W2018705190 date "1970-05-01" @default.
- W2018705190 modified "2023-09-27" @default.
- W2018705190 title "Effects of chronic nicotine, acute hypoxia, and their interactions on myocardial enzymes" @default.
- W2018705190 cites W103686952 @default.
- W2018705190 cites W146351861 @default.
- W2018705190 cites W1494849314 @default.
- W2018705190 cites W1970863968 @default.
- W2018705190 cites W1973889573 @default.
- W2018705190 cites W1974818827 @default.
- W2018705190 cites W2023697266 @default.
- W2018705190 cites W2028449082 @default.
- W2018705190 cites W2045962273 @default.
- W2018705190 cites W2075665776 @default.
- W2018705190 cites W2083445832 @default.
- W2018705190 cites W2085071335 @default.
- W2018705190 cites W2087824113 @default.
- W2018705190 cites W2088107565 @default.
- W2018705190 cites W2099544839 @default.
- W2018705190 cites W2148272914 @default.
- W2018705190 cites W2160751727 @default.
- W2018705190 cites W2168121383 @default.
- W2018705190 cites W2406427508 @default.
- W2018705190 cites W9708610 @default.
- W2018705190 doi "https://doi.org/10.1016/0041-008x(70)90070-0" @default.
- W2018705190 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4393062" @default.
- W2018705190 hasPublicationYear "1970" @default.
- W2018705190 type Work @default.
- W2018705190 sameAs 2018705190 @default.
- W2018705190 citedByCount "1" @default.
- W2018705190 crossrefType "journal-article" @default.
- W2018705190 hasAuthorship W2018705190A5000505165 @default.
- W2018705190 hasAuthorship W2018705190A5050317257 @default.
- W2018705190 hasConcept C126322002 @default.
- W2018705190 hasConcept C134018914 @default.
- W2018705190 hasConcept C178790620 @default.
- W2018705190 hasConcept C181199279 @default.
- W2018705190 hasConcept C185592680 @default.
- W2018705190 hasConcept C2776317432 @default.
- W2018705190 hasConcept C2776901170 @default.
- W2018705190 hasConcept C2777667214 @default.
- W2018705190 hasConcept C2777989768 @default.
- W2018705190 hasConcept C2779547902 @default.
- W2018705190 hasConcept C38485361 @default.
- W2018705190 hasConcept C540031477 @default.
- W2018705190 hasConcept C55493867 @default.
- W2018705190 hasConcept C71240020 @default.
- W2018705190 hasConcept C71924100 @default.
- W2018705190 hasConcept C75520062 @default.
- W2018705190 hasConcept C7836513 @default.
- W2018705190 hasConcept C86803240 @default.
- W2018705190 hasConcept C98274493 @default.
- W2018705190 hasConceptScore W2018705190C126322002 @default.
- W2018705190 hasConceptScore W2018705190C134018914 @default.
- W2018705190 hasConceptScore W2018705190C178790620 @default.
- W2018705190 hasConceptScore W2018705190C181199279 @default.
- W2018705190 hasConceptScore W2018705190C185592680 @default.
- W2018705190 hasConceptScore W2018705190C2776317432 @default.
- W2018705190 hasConceptScore W2018705190C2776901170 @default.
- W2018705190 hasConceptScore W2018705190C2777667214 @default.
- W2018705190 hasConceptScore W2018705190C2777989768 @default.
- W2018705190 hasConceptScore W2018705190C2779547902 @default.
- W2018705190 hasConceptScore W2018705190C38485361 @default.
- W2018705190 hasConceptScore W2018705190C540031477 @default.
- W2018705190 hasConceptScore W2018705190C55493867 @default.
- W2018705190 hasConceptScore W2018705190C71240020 @default.
- W2018705190 hasConceptScore W2018705190C71924100 @default.
- W2018705190 hasConceptScore W2018705190C75520062 @default.
- W2018705190 hasConceptScore W2018705190C7836513 @default.
- W2018705190 hasConceptScore W2018705190C86803240 @default.
- W2018705190 hasConceptScore W2018705190C98274493 @default.
- W2018705190 hasLocation W20187051901 @default.
- W2018705190 hasLocation W20187051902 @default.
- W2018705190 hasOpenAccess W2018705190 @default.
- W2018705190 hasPrimaryLocation W20187051901 @default.
- W2018705190 hasRelatedWork W2024599954 @default.
- W2018705190 hasRelatedWork W2029205859 @default.
- W2018705190 hasRelatedWork W2057983183 @default.
- W2018705190 hasRelatedWork W2105068995 @default.
- W2018705190 hasRelatedWork W2133617154 @default.
- W2018705190 hasRelatedWork W2322900513 @default.
- W2018705190 hasRelatedWork W2323174039 @default.
- W2018705190 hasRelatedWork W2748952813 @default.
- W2018705190 hasRelatedWork W2899084033 @default.
- W2018705190 hasRelatedWork W3141700921 @default.
- W2018705190 isParatext "false" @default.
- W2018705190 isRetracted "false" @default.
- W2018705190 magId "2018705190" @default.
- W2018705190 workType "article" @default.