FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018759710> ?p ?o ?g. }

• W2018759710 endingPage "816" @default.
• W2018759710 startingPage "809" @default.
• W2018759710 abstract "Objective: To assess the impact of prior exposure to single-dose nevirapine (sdNVP) on mother-to-child transmission and genotypic resistance in HIV-infected women. Design: Prospective study of 120 women exposed to the HIVNET 012 sdNVP regimen in two successive pregnancies and 240 antiretroviral (ARV)-naïve, multiparous women who received sdNVP for the first time. Results: One hundred and eight of 120 and 193 of 240 women returned for a postpartum visit by 6 weeks. HIV-1 was detected in 11.1% (95% confidence interval = 5.9–18.6) of the infants of women previously exposed to sdNVP and 4.2% (95% confidence interval = 1.3–7.0) of those exposed for the first time (P = 0.028). Rates of maternal HIV-1 genotypic resistance at 6 weeks postdelivery were 37.5% and 46.4%, respectively (P = 0.119). Sensitive mutation-specific real-time PCR testing found three of 12 previously exposed women who transmitted HIV-1 to their infants had either K103N or Y181C at baseline compared with one of eight ARV-naïve, transmitting women who had Y181C. None of 40 randomly selected nontransmitting women from either group had detectable NVP resistance mutations prior to sdNVP exposure. Conclusion: This study shows that effectiveness of sdNVP may be compromised by prior exposure to sdNVP, although the increase in transmission rate after prior exposure could not be explained by the detection of NVP resistance mutations prior to re-exposure as measured both by standard genotyping and highly sensitive allele-specific PCR assays. Furthermore, transmission rates of women with prior exposure were not higher than those reported elsewhere." @default.
• W2018759710 created "2016-06-24" @default.
• W2018759710 creator A5011671349 @default.
• W2018759710 creator A5013036446 @default.
• W2018759710 creator A5018687790 @default.
• W2018759710 creator A5029681666 @default.
• W2018759710 creator A5031077639 @default.
• W2018759710 creator A5038341964 @default.
• W2018759710 creator A5040572250 @default.
• W2018759710 creator A5043096547 @default.
• W2018759710 creator A5045349195 @default.
• W2018759710 creator A5080719777 @default.
• W2018759710 creator A5086110206 @default.
• W2018759710 creator A5088240247 @default.
• W2018759710 date "2009-04-27" @default.
• W2018759710 modified "2023-10-16" @default.
• W2018759710 title "Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistance" @default.
• W2018759710 cites W1497870368 @default.
• W2018759710 cites W1966822156 @default.
• W2018759710 cites W1968792515 @default.
• W2018759710 cites W1969901476 @default.
• W2018759710 cites W1987858510 @default.
• W2018759710 cites W1990105675 @default.
• W2018759710 cites W2010565692 @default.
• W2018759710 cites W2014366116 @default.
• W2018759710 cites W2024337966 @default.
• W2018759710 cites W2047892068 @default.
• W2018759710 cites W2057907270 @default.
• W2018759710 cites W2067044060 @default.
• W2018759710 cites W2067880257 @default.
• W2018759710 cites W2070439222 @default.
• W2018759710 cites W2081745197 @default.
• W2018759710 cites W2087734376 @default.
• W2018759710 cites W2094542703 @default.
• W2018759710 cites W2101141605 @default.
• W2018759710 cites W2104966707 @default.
• W2018759710 cites W2118435139 @default.
• W2018759710 cites W2126771378 @default.
• W2018759710 cites W2139250164 @default.
• W2018759710 cites W2144891663 @default.
• W2018759710 cites W2147072996 @default.
• W2018759710 cites W2148684707 @default.
• W2018759710 cites W2154959052 @default.
• W2018759710 cites W2157380363 @default.
• W2018759710 cites W2170947401 @default.
• W2018759710 cites W2252582782 @default.
• W2018759710 cites W2262700604 @default.
• W2018759710 cites W2404850008 @default.
• W2018759710 cites W3018468690 @default.
• W2018759710 cites W4239540786 @default.
• W2018759710 doi "https://doi.org/10.1097/qad.0b013e328323ad49" @default.
• W2018759710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19287298" @default.
• W2018759710 hasPublicationYear "2009" @default.
• W2018759710 type Work @default.
• W2018759710 sameAs 2018759710 @default.
• W2018759710 citedByCount "22" @default.
• W2018759710 countsByYear W20187597102013 @default.
• W2018759710 countsByYear W20187597102014 @default.
• W2018759710 countsByYear W20187597102015 @default.
• W2018759710 countsByYear W20187597102017 @default.
• W2018759710 countsByYear W20187597102019 @default.
• W2018759710 countsByYear W20187597102021 @default.
• W2018759710 crossrefType "journal-article" @default.
• W2018759710 hasAuthorship W2018759710A5011671349 @default.
• W2018759710 hasAuthorship W2018759710A5013036446 @default.
• W2018759710 hasAuthorship W2018759710A5018687790 @default.
• W2018759710 hasAuthorship W2018759710A5029681666 @default.
• W2018759710 hasAuthorship W2018759710A5031077639 @default.
• W2018759710 hasAuthorship W2018759710A5038341964 @default.
• W2018759710 hasAuthorship W2018759710A5040572250 @default.
• W2018759710 hasAuthorship W2018759710A5043096547 @default.
• W2018759710 hasAuthorship W2018759710A5045349195 @default.
• W2018759710 hasAuthorship W2018759710A5080719777 @default.
• W2018759710 hasAuthorship W2018759710A5086110206 @default.
• W2018759710 hasAuthorship W2018759710A5088240247 @default.
• W2018759710 hasBestOaLocation W20187597101 @default.
• W2018759710 hasConcept C104317684 @default.
• W2018759710 hasConcept C119599485 @default.
• W2018759710 hasConcept C126322002 @default.
• W2018759710 hasConcept C127413603 @default.
• W2018759710 hasConcept C131872663 @default.
• W2018759710 hasConcept C135763542 @default.
• W2018759710 hasConcept C142462285 @default.
• W2018759710 hasConcept C159047783 @default.
• W2018759710 hasConcept C2777351918 @default.
• W2018759710 hasConcept C2779130552 @default.
• W2018759710 hasConcept C2779234561 @default.
• W2018759710 hasConcept C2781413609 @default.
• W2018759710 hasConcept C2993143319 @default.
• W2018759710 hasConcept C3013748606 @default.
• W2018759710 hasConcept C31467283 @default.
• W2018759710 hasConcept C44249647 @default.
• W2018759710 hasConcept C54355233 @default.
• W2018759710 hasConcept C71924100 @default.
• W2018759710 hasConcept C761482 @default.
• W2018759710 hasConcept C86803240 @default.
• W2018759710 hasConceptScore W2018759710C104317684 @default.
• W2018759710 hasConceptScore W2018759710C119599485 @default.

• next