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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018760184> ?p ?o ?g. }

• W2018760184 abstract "We explore the large-scale behavior of nucleotide compositional strand asymmetries along human chromosomes. As we observe for 7 of 9 origins of replication experimentally identified so far, the (TA+GC) skew displays rather sharp upward jumps, with a linear decreasing profile in between two successive jumps. We present a model of replication with well positioned replication origins and random terminations that accounts for the observed characteristic serrated skew profiles. We succeed in identifying 287 pairs of putative adjacent replication origins with an origin spacing approximately 1-2 Mbp that are likely to correspond to replication foci observed in interphase nuclei and recognized as stable structures that persist throughout subsequent cell generations." @default.
• W2018760184 created "2016-06-24" @default.
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• W2018760184 date "2005-06-23" @default.
• W2018760184 modified "2023-10-17" @default.
• W2018760184 title "From DNA Sequence Analysis to Modeling Replication in the Human Genome" @default.
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• W2018760184 doi "https://doi.org/10.1103/physrevlett.94.248103" @default.
• W2018760184 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16090582" @default.
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