FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018773251> ?p ?o ?g. }

• W2018773251 endingPage "26" @default.
• W2018773251 startingPage "15" @default.
• W2018773251 abstract "The binding, mobility, and mode of cell entry of the plant toxin ricin (or RCAII) were investigated on susceptible and partially resistant murine cell lines. When susceptible cells (SV40-transformed 3T3 fibroblast cells and BW5147 lymphoma cells) were examined, ricin bound rapidly, induced endocytosis, and entered the cell cytoplasm via broken endocytotic vesicles to inhibit cell protein synthesis, as found previously (1). Addition of lactose within 15 min after initial ricin binding prevented toxicity. After this time lactose addition no longer blocked the inhibition of protein synthesis. In a partially resistant lymphoma (BW5147/RCA3) that shows only a slight reduction in the total number of ricin-binding sites, ricin bound rapidly to the cell surface, but was endocytosed significantly less at low ricin doses compared to its parental line, indicating a possible difference in cell surface behavior. The exposed surface proteins on the BW5147 parental and BW5147/RCA3 resistnat lines were examined by 125I-labeling utilizing lactoperoxidase-catalyzed iodination. The radiolabeled components were solubilized and separated by slab electrophoresis in sodium dodecyl sulfate. Autoradiograms of the slab gels indicated that two surface components of approximately 80,000 and 35,000 mol wt were much less exposed or were missing on the resistant line." @default.
• W2018773251 created "2016-06-24" @default.
• W2018773251 creator A5000824752 @default.
• W2018773251 creator A5015005165 @default.
• W2018773251 creator A5088154120 @default.
• W2018773251 date "1976-01-01" @default.
• W2018773251 modified "2023-09-30" @default.
• W2018773251 title "Cell surface receptors and their dynamics on toxin-treated malignant cells" @default.
• W2018773251 cites W1494615802 @default.
• W2018773251 cites W1532520741 @default.
• W2018773251 cites W170897292 @default.
• W2018773251 cites W1773433648 @default.
• W2018773251 cites W1965853612 @default.
• W2018773251 cites W1967020391 @default.
• W2018773251 cites W1970071031 @default.
• W2018773251 cites W1971841250 @default.
• W2018773251 cites W1991655565 @default.
• W2018773251 cites W1991874195 @default.
• W2018773251 cites W1995777112 @default.
• W2018773251 cites W2000319039 @default.
• W2018773251 cites W2006668053 @default.
• W2018773251 cites W2011296435 @default.
• W2018773251 cites W2019278374 @default.
• W2018773251 cites W2025452220 @default.
• W2018773251 cites W2026069881 @default.
• W2018773251 cites W2035219404 @default.
• W2018773251 cites W2037148374 @default.
• W2018773251 cites W2041193908 @default.
• W2018773251 cites W2049526841 @default.
• W2018773251 cites W2052488578 @default.
• W2018773251 cites W2052675917 @default.
• W2018773251 cites W2055571521 @default.
• W2018773251 cites W2056564405 @default.
• W2018773251 cites W2059697726 @default.
• W2018773251 cites W2060180464 @default.
• W2018773251 cites W2064030572 @default.
• W2018773251 cites W2069004374 @default.
• W2018773251 cites W2071115616 @default.
• W2018773251 cites W2075507370 @default.
• W2018773251 cites W2085649019 @default.
• W2018773251 cites W2090474174 @default.
• W2018773251 cites W2100837269 @default.
• W2018773251 cites W2104475379 @default.
• W2018773251 cites W2106418432 @default.
• W2018773251 cites W2109618118 @default.
• W2018773251 cites W2113159763 @default.
• W2018773251 cites W2144543060 @default.
• W2018773251 cites W2145288036 @default.
• W2018773251 cites W2156615308 @default.
• W2018773251 cites W2336728022 @default.
• W2018773251 cites W4242856158 @default.
• W2018773251 doi "https://doi.org/10.1002/jss.400040103" @default.
• W2018773251 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1256060" @default.
• W2018773251 hasPublicationYear "1976" @default.
• W2018773251 type Work @default.
• W2018773251 sameAs 2018773251 @default.
• W2018773251 citedByCount "31" @default.
• W2018773251 crossrefType "journal-article" @default.
• W2018773251 hasAuthorship W2018773251A5000824752 @default.
• W2018773251 hasAuthorship W2018773251A5015005165 @default.
• W2018773251 hasAuthorship W2018773251A5088154120 @default.
• W2018773251 hasConcept C1491633281 @default.
• W2018773251 hasConcept C153911025 @default.
• W2018773251 hasConcept C170493617 @default.
• W2018773251 hasConcept C185592680 @default.
• W2018773251 hasConcept C190062978 @default.
• W2018773251 hasConcept C2777200438 @default.
• W2018773251 hasConcept C2777367657 @default.
• W2018773251 hasConcept C28005876 @default.
• W2018773251 hasConcept C54355233 @default.
• W2018773251 hasConcept C55493867 @default.
• W2018773251 hasConcept C81885089 @default.
• W2018773251 hasConcept C86803240 @default.
• W2018773251 hasConceptScore W2018773251C1491633281 @default.
• W2018773251 hasConceptScore W2018773251C153911025 @default.
• W2018773251 hasConceptScore W2018773251C170493617 @default.
• W2018773251 hasConceptScore W2018773251C185592680 @default.
• W2018773251 hasConceptScore W2018773251C190062978 @default.
• W2018773251 hasConceptScore W2018773251C2777200438 @default.
• W2018773251 hasConceptScore W2018773251C2777367657 @default.
• W2018773251 hasConceptScore W2018773251C28005876 @default.
• W2018773251 hasConceptScore W2018773251C54355233 @default.
• W2018773251 hasConceptScore W2018773251C55493867 @default.
• W2018773251 hasConceptScore W2018773251C81885089 @default.
• W2018773251 hasConceptScore W2018773251C86803240 @default.
• W2018773251 hasIssue "1" @default.
• W2018773251 hasLocation W20187732511 @default.
• W2018773251 hasLocation W20187732512 @default.
• W2018773251 hasOpenAccess W2018773251 @default.
• W2018773251 hasPrimaryLocation W20187732511 @default.
• W2018773251 hasRelatedWork W1964101603 @default.
• W2018773251 hasRelatedWork W1968282864 @default.
• W2018773251 hasRelatedWork W2072246125 @default.
• W2018773251 hasRelatedWork W2073878526 @default.
• W2018773251 hasRelatedWork W2096839719 @default.
• W2018773251 hasRelatedWork W2112015565 @default.
• W2018773251 hasRelatedWork W2398288187 @default.
• W2018773251 hasRelatedWork W2620565042 @default.

• next