FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018773845> ?p ?o ?g. }

• W2018773845 endingPage "9692" @default.
• W2018773845 startingPage "9687" @default.
• W2018773845 abstract "Nitroxyl (HNO/NO-), the reduced form of nitric oxide, has gained attention based on its separate chemistry and biology from nitric oxide. The inherent reactivity of HNO requires new and mechanistically unique donors for the detailed study of HNO chemistry and biology. Oxidation of cyclohexanone oxime with lead tetraacetate yields 1-nitrosocyclohexyl acetate, whereas oxidation of oximes in the presence of excess carboxylic acid gives various acyloxy nitroso compounds. These bright blue compounds exist as monomers as indicated by their infrared, proton, and carbon NMR spectra, and X-ray crystallographic analysis reveals the nitroso groups possess a “nitroxyl-like” bent configuration. Hydrolysis of these compounds produces nitrous oxide, the dimerization and dehydration product of HNO, and provides evidence for the intermediacy of HNO. Both thiols and oxidative metal complexes inhibit nitrous oxide formation. Hydrolysis of these compounds in the presence of ferric heme complexes forms ferrous nitrosyl complexes providing further evidence for the intermediacy of HNO. Kinetic analysis shows that the rate of hydrolysis depends on pH and the structure of the acyl group of the acyloxy nitroso compound. These compounds relax pre-constricted rat aortic rings similar to known HNO donors. Together, these results identify acyloxy nitroso compounds as a new class of HNO donors." @default.
• W2018773845 created "2016-06-24" @default.
• W2018773845 creator A5021751784 @default.
• W2018773845 creator A5032298661 @default.
• W2018773845 creator A5034296929 @default.
• W2018773845 creator A5054244329 @default.
• W2018773845 creator A5082924570 @default.
• W2018773845 date "2006-07-12" @default.
• W2018773845 modified "2023-09-28" @default.
• W2018773845 title "Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO)" @default.
• W2018773845 cites W1909598551 @default.
• W2018773845 cites W1964058023 @default.
• W2018773845 cites W1967253107 @default.
• W2018773845 cites W1972297823 @default.
• W2018773845 cites W1977177442 @default.
• W2018773845 cites W1993414071 @default.
• W2018773845 cites W1999441551 @default.
• W2018773845 cites W1999952230 @default.
• W2018773845 cites W2004325558 @default.
• W2018773845 cites W2006144064 @default.
• W2018773845 cites W2010361160 @default.
• W2018773845 cites W2026005642 @default.
• W2018773845 cites W2034592170 @default.
• W2018773845 cites W2036551340 @default.
• W2018773845 cites W2045429393 @default.
• W2018773845 cites W2050264954 @default.
• W2018773845 cites W2065281025 @default.
• W2018773845 cites W2068395093 @default.
• W2018773845 cites W2086043766 @default.
• W2018773845 cites W2108772802 @default.
• W2018773845 cites W2138011583 @default.
• W2018773845 cites W2160947287 @default.
• W2018773845 cites W2169232518 @default.
• W2018773845 cites W2312635186 @default.
• W2018773845 cites W2325775449 @default.
• W2018773845 cites W2949097102 @default.
• W2018773845 cites W2950571127 @default.
• W2018773845 doi "https://doi.org/10.1021/ja062365a" @default.
• W2018773845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16866522" @default.
• W2018773845 hasPublicationYear "2006" @default.
• W2018773845 type Work @default.
• W2018773845 sameAs 2018773845 @default.
• W2018773845 citedByCount "108" @default.
• W2018773845 countsByYear W20187738452012 @default.
• W2018773845 countsByYear W20187738452013 @default.
• W2018773845 countsByYear W20187738452014 @default.
• W2018773845 countsByYear W20187738452015 @default.
• W2018773845 countsByYear W20187738452016 @default.
• W2018773845 countsByYear W20187738452017 @default.
• W2018773845 countsByYear W20187738452018 @default.
• W2018773845 countsByYear W20187738452019 @default.
• W2018773845 countsByYear W20187738452020 @default.
• W2018773845 countsByYear W20187738452021 @default.
• W2018773845 countsByYear W20187738452022 @default.
• W2018773845 countsByYear W20187738452023 @default.
• W2018773845 crossrefType "journal-article" @default.
• W2018773845 hasAuthorship W2018773845A5021751784 @default.
• W2018773845 hasAuthorship W2018773845A5032298661 @default.
• W2018773845 hasAuthorship W2018773845A5034296929 @default.
• W2018773845 hasAuthorship W2018773845A5054244329 @default.
• W2018773845 hasAuthorship W2018773845A5082924570 @default.
• W2018773845 hasConcept C155647269 @default.
• W2018773845 hasConcept C161790260 @default.
• W2018773845 hasConcept C178790620 @default.
• W2018773845 hasConcept C179104552 @default.
• W2018773845 hasConcept C185592680 @default.
• W2018773845 hasConcept C2775932965 @default.
• W2018773845 hasConcept C2775999725 @default.
• W2018773845 hasConcept C2776142628 @default.
• W2018773845 hasConcept C2776179834 @default.
• W2018773845 hasConcept C2776384668 @default.
• W2018773845 hasConcept C2779648554 @default.
• W2018773845 hasConcept C2780450521 @default.
• W2018773845 hasConcept C2909807293 @default.
• W2018773845 hasConcept C94412978 @default.
• W2018773845 hasConceptScore W2018773845C155647269 @default.
• W2018773845 hasConceptScore W2018773845C161790260 @default.
• W2018773845 hasConceptScore W2018773845C178790620 @default.
• W2018773845 hasConceptScore W2018773845C179104552 @default.
• W2018773845 hasConceptScore W2018773845C185592680 @default.
• W2018773845 hasConceptScore W2018773845C2775932965 @default.
• W2018773845 hasConceptScore W2018773845C2775999725 @default.
• W2018773845 hasConceptScore W2018773845C2776142628 @default.
• W2018773845 hasConceptScore W2018773845C2776179834 @default.
• W2018773845 hasConceptScore W2018773845C2776384668 @default.
• W2018773845 hasConceptScore W2018773845C2779648554 @default.
• W2018773845 hasConceptScore W2018773845C2780450521 @default.
• W2018773845 hasConceptScore W2018773845C2909807293 @default.
• W2018773845 hasConceptScore W2018773845C94412978 @default.
• W2018773845 hasIssue "30" @default.
• W2018773845 hasLocation W20187738451 @default.
• W2018773845 hasLocation W20187738452 @default.
• W2018773845 hasOpenAccess W2018773845 @default.
• W2018773845 hasPrimaryLocation W20187738451 @default.
• W2018773845 hasRelatedWork W1513474280 @default.
• W2018773845 hasRelatedWork W1967766309 @default.
• W2018773845 hasRelatedWork W1993870957 @default.
• W2018773845 hasRelatedWork W2015791471 @default.

• next