FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018840635> ?p ?o ?g. }

• W2018840635 endingPage "460" @default.
• W2018840635 startingPage "453" @default.
• W2018840635 abstract "Background: Tacrolimus is a new‐generation immunosuppressant as successful as cyclosporin in suppressing organ transplant rejection. Although cyclosporin is known to cause gingival enlargement (GE), tacrolimus has not been associated with this condition. We sought to explore the prevalence of GE among renal transplant recipients (RTRs) in relation to cyclosporin and tacrolimus while controlling for the effect of calcium channel blockers (CCBs) and supragingival plaque. Methods: RTRs were recruited from our institution's Kidney Transplant Unit. Participants completed a standardized questionnaire and received a complete oral examination, including a soft tissue examination and a periodontal examination measuring probing depth, recession, bleeding on probing, plaque index (PI), and GE. Results: Among 115 RTRs, 39 (34%) presented with GE, with the highest prevalence among those taking cyclosporin and CCBs (76%) and the lowest among tacrolimus users not on a CCB (15%). Tacrolimus was not found to be associated with GE. Cyclosporin was found to be associated with GE in a univariate analysis stratified by the use of CCBs, but multivariate analysis revealed that the only significant risk factors for GE were the use of CCBs and the widespread presence of abundant supragingival plaque (PI ≥2 on >40% of tooth surfaces). Conclusions: This study confirmed that tacrolimus is not associated with GE. Cyclosporin taken at the currently recommended low dosage and not in combination with a CCB may not be associated with a significant risk for GE in individuals with good oral hygiene. CCBs should be avoided among patients taking cyclosporin and those with poor oral hygiene." @default.
• W2018840635 created "2016-06-24" @default.
• W2018840635 creator A5004892231 @default.
• W2018840635 creator A5076942056 @default.
• W2018840635 creator A5080941195 @default.
• W2018840635 date "2008-03-01" @default.
• W2018840635 modified "2023-10-12" @default.
• W2018840635 title "Gingival Enlargement Among Renal Transplant Recipients in the Era of New‐Generation Immunosuppressants" @default.
• W2018840635 cites W1964881088 @default.
• W2018840635 cites W1983034326 @default.
• W2018840635 cites W1996248247 @default.
• W2018840635 cites W2004839437 @default.
• W2018840635 cites W2008175916 @default.
• W2018840635 cites W2008808499 @default.
• W2018840635 cites W2012146960 @default.
• W2018840635 cites W2013042705 @default.
• W2018840635 cites W2017797465 @default.
• W2018840635 cites W2024481478 @default.
• W2018840635 cites W2034934147 @default.
• W2018840635 cites W2034937670 @default.
• W2018840635 cites W2037025693 @default.
• W2018840635 cites W2042331413 @default.
• W2018840635 cites W2043785865 @default.
• W2018840635 cites W2060878143 @default.
• W2018840635 cites W2079804998 @default.
• W2018840635 cites W2086111488 @default.
• W2018840635 cites W2096145898 @default.
• W2018840635 cites W2103477432 @default.
• W2018840635 cites W2107228383 @default.
• W2018840635 cites W2113609591 @default.
• W2018840635 cites W2114726336 @default.
• W2018840635 cites W2115477316 @default.
• W2018840635 cites W2123463521 @default.
• W2018840635 cites W2130373328 @default.
• W2018840635 cites W2136663387 @default.
• W2018840635 cites W2140331009 @default.
• W2018840635 cites W2155925014 @default.
• W2018840635 cites W2157290023 @default.
• W2018840635 cites W2166027006 @default.
• W2018840635 cites W2167435614 @default.
• W2018840635 cites W2172101511 @default.
• W2018840635 cites W2224116784 @default.
• W2018840635 cites W3094860599 @default.
• W2018840635 cites W4234303059 @default.
• W2018840635 doi "https://doi.org/10.1902/jop.2008.070434" @default.
• W2018840635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18315427" @default.
• W2018840635 hasPublicationYear "2008" @default.
• W2018840635 type Work @default.
• W2018840635 sameAs 2018840635 @default.
• W2018840635 citedByCount "39" @default.
• W2018840635 countsByYear W20188406352012 @default.
• W2018840635 countsByYear W20188406352013 @default.
• W2018840635 countsByYear W20188406352014 @default.
• W2018840635 countsByYear W20188406352015 @default.
• W2018840635 countsByYear W20188406352016 @default.
• W2018840635 countsByYear W20188406352018 @default.
• W2018840635 countsByYear W20188406352019 @default.
• W2018840635 countsByYear W20188406352020 @default.
• W2018840635 countsByYear W20188406352021 @default.
• W2018840635 crossrefType "journal-article" @default.
• W2018840635 hasAuthorship W2018840635A5004892231 @default.
• W2018840635 hasAuthorship W2018840635A5076942056 @default.
• W2018840635 hasAuthorship W2018840635A5080941195 @default.
• W2018840635 hasConcept C126322002 @default.
• W2018840635 hasConcept C144301174 @default.
• W2018840635 hasConcept C199343813 @default.
• W2018840635 hasConcept C2779193238 @default.
• W2018840635 hasConcept C2780090536 @default.
• W2018840635 hasConcept C2780385504 @default.
• W2018840635 hasConcept C2909675724 @default.
• W2018840635 hasConcept C2911091166 @default.
• W2018840635 hasConcept C2992666275 @default.
• W2018840635 hasConcept C38180746 @default.
• W2018840635 hasConcept C515851188 @default.
• W2018840635 hasConcept C71924100 @default.
• W2018840635 hasConcept C90924648 @default.
• W2018840635 hasConceptScore W2018840635C126322002 @default.
• W2018840635 hasConceptScore W2018840635C144301174 @default.
• W2018840635 hasConceptScore W2018840635C199343813 @default.
• W2018840635 hasConceptScore W2018840635C2779193238 @default.
• W2018840635 hasConceptScore W2018840635C2780090536 @default.
• W2018840635 hasConceptScore W2018840635C2780385504 @default.
• W2018840635 hasConceptScore W2018840635C2909675724 @default.
• W2018840635 hasConceptScore W2018840635C2911091166 @default.
• W2018840635 hasConceptScore W2018840635C2992666275 @default.
• W2018840635 hasConceptScore W2018840635C38180746 @default.
• W2018840635 hasConceptScore W2018840635C515851188 @default.
• W2018840635 hasConceptScore W2018840635C71924100 @default.
• W2018840635 hasConceptScore W2018840635C90924648 @default.
• W2018840635 hasIssue "3" @default.
• W2018840635 hasLocation W20188406351 @default.
• W2018840635 hasLocation W20188406352 @default.
• W2018840635 hasOpenAccess W2018840635 @default.
• W2018840635 hasPrimaryLocation W20188406351 @default.
• W2018840635 hasRelatedWork W1824591903 @default.
• W2018840635 hasRelatedWork W190693608 @default.
• W2018840635 hasRelatedWork W2018840635 @default.
• W2018840635 hasRelatedWork W2062823147 @default.

• next