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- W2018847403 abstract "Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) with Panton-Valentine leukocidin (PVL) genes is increasing worldwide. Nosocomial outbreak-derived (hospital-acquired) MRSA (HA-MRSA) in Japan in the 1980s was also largely PVL+. PVL+ HA-MRSA and CA-MRSA shared the same multi-locus sequence type (ST30) and methicillin resistance cassette (SCCmecIV), but were divergent in oxacillin resistance, spa typing, PFGE analysis or clfA gene analysis. PVL+ HA-MRSA, which probably originated in PVL+ S. aureus ST30, was highly adhesive (carrying cna and bbp genes), highly-toxic (carrying luk PV and sea genes) and highly drug-resistant. PVL+ HA-MRSA was once replaced by other PVL− HA-MRSA (e.g., ST5), and is re-emerging as CA-MRSA." @default.
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- W2018847403 date "2006-03-29" @default.
- W2018847403 modified "2023-09-23" @default.
- W2018847403 title "Molecular nature of methicillin-resistant<i>Staphylococcus aureus</i>derived from explosive nosocomial outbreaks of the 1980s in Japan" @default.
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- W2018847403 doi "https://doi.org/10.1016/j.febslet.2006.03.049" @default.
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