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- W2018865905 abstract "Cardiotoxicity is one of the most significant adverse effects of cancer treatment, and is responsible for considerable morbidity and mortality. Among the effects of chemotherapeutic agents on the cardiovascular system, the most frequent and serious is heart failure with ventricular systolic dysfunction. Other toxic effects include hypertension, thromboembolic disease, pericardial disease, arrhythmias and myocardial ischemia. For several decades, cancer therapy-induced cardiomyopathy was almost exclusively associated with the use of cumulative doses of anthracyclines, which cause permanent damage at the cellular level. However, new therapeutic agents, such as the monoclonal antibody trastuzumab, induce transient reversible myocyte dysfunction which is unrelated to the dose used. Early identification of potential cardiovascular injury, accurate diagnosis of cardiotoxic events and implementation of appropriate monitoring plans are essential in patients with cancer. Close cooperation between cardiologists and oncologists is thus crucial, in order to balance the risks and benefits of cardiotoxic anticancer therapy. In this article we review the various responses to cardiotoxic cancer treatments and their relationship with the main antineoplastic drugs used in clinical practice. In addition, we discuss the main guidelines on detection and monitoring of cardiotoxicity in patients with cancer." @default.
- W2018865905 created "2016-06-24" @default.
- W2018865905 creator A5007213349 @default.
- W2018865905 creator A5052974638 @default.
- W2018865905 creator A5054708047 @default.
- W2018865905 creator A5068149383 @default.
- W2018865905 date "2013-05-01" @default.
- W2018865905 modified "2023-10-13" @default.
- W2018865905 title "Cardiotoxicidade associada à terapêutica oncológica: mecanismos fisiopatológicos e estratégias de prevenção" @default.
- W2018865905 cites W1535876276 @default.
- W2018865905 cites W1572154950 @default.
- W2018865905 cites W1791262955 @default.
- W2018865905 cites W1796787464 @default.
- W2018865905 cites W1966825452 @default.
- W2018865905 cites W1976275744 @default.
- W2018865905 cites W1978080273 @default.
- W2018865905 cites W1980309558 @default.
- W2018865905 cites W1980677762 @default.
- W2018865905 cites W1981347362 @default.
- W2018865905 cites W1982210988 @default.
- W2018865905 cites W1983530651 @default.
- W2018865905 cites W1984007340 @default.
- W2018865905 cites W1989753015 @default.
- W2018865905 cites W1991341754 @default.
- W2018865905 cites W1996423501 @default.
- W2018865905 cites W2001122447 @default.
- W2018865905 cites W2006424018 @default.
- W2018865905 cites W2006571105 @default.
- W2018865905 cites W2008388668 @default.
- W2018865905 cites W2015435732 @default.
- W2018865905 cites W2018426258 @default.
- W2018865905 cites W2018925169 @default.
- W2018865905 cites W2026707626 @default.
- W2018865905 cites W2027455996 @default.
- W2018865905 cites W2029542561 @default.
- W2018865905 cites W2029926676 @default.
- W2018865905 cites W2030177226 @default.
- W2018865905 cites W2032687462 @default.
- W2018865905 cites W2033538830 @default.
- W2018865905 cites W2035457896 @default.
- W2018865905 cites W2035499272 @default.
- W2018865905 cites W2036154804 @default.
- W2018865905 cites W2036536995 @default.
- W2018865905 cites W2043253666 @default.
- W2018865905 cites W2043704268 @default.
- W2018865905 cites W2044101767 @default.
- W2018865905 cites W2044987966 @default.
- W2018865905 cites W2045570557 @default.
- W2018865905 cites W2050674912 @default.
- W2018865905 cites W2053166784 @default.
- W2018865905 cites W2059487482 @default.
- W2018865905 cites W2061452374 @default.
- W2018865905 cites W2066048575 @default.
- W2018865905 cites W2070431417 @default.
- W2018865905 cites W2075426045 @default.
- W2018865905 cites W2078879084 @default.
- W2018865905 cites W2081190745 @default.
- W2018865905 cites W2082685349 @default.
- W2018865905 cites W2090101539 @default.
- W2018865905 cites W2093202724 @default.
- W2018865905 cites W2098268167 @default.
- W2018865905 cites W2104179452 @default.
- W2018865905 cites W2104868004 @default.
- W2018865905 cites W2105307617 @default.
- W2018865905 cites W2109775164 @default.
- W2018865905 cites W2110444464 @default.
- W2018865905 cites W2111426313 @default.
- W2018865905 cites W2115100262 @default.
- W2018865905 cites W2118761610 @default.
- W2018865905 cites W2120584854 @default.
- W2018865905 cites W2121785313 @default.
- W2018865905 cites W2121981428 @default.
- W2018865905 cites W2122074158 @default.
- W2018865905 cites W2122472092 @default.
- W2018865905 cites W2122724278 @default.
- W2018865905 cites W2123366208 @default.
- W2018865905 cites W2130860651 @default.
- W2018865905 cites W2133528707 @default.
- W2018865905 cites W2138179458 @default.
- W2018865905 cites W2139048802 @default.
- W2018865905 cites W2141469083 @default.
- W2018865905 cites W2142681531 @default.
- W2018865905 cites W2144124503 @default.
- W2018865905 cites W2145860233 @default.
- W2018865905 cites W2146035745 @default.
- W2018865905 cites W2147809056 @default.
- W2018865905 cites W2148209445 @default.
- W2018865905 cites W2149908785 @default.
- W2018865905 cites W2153156872 @default.
- W2018865905 cites W2158276380 @default.
- W2018865905 cites W2160329331 @default.
- W2018865905 cites W2161082810 @default.
- W2018865905 cites W2165824128 @default.
- W2018865905 cites W2168807041 @default.
- W2018865905 cites W2171345666 @default.
- W2018865905 cites W2171747665 @default.
- W2018865905 cites W2328452031 @default.
- W2018865905 cites W2769648988 @default.