FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018879423> ?p ?o ?g. }

• W2018879423 endingPage "45" @default.
• W2018879423 startingPage "20" @default.
• W2018879423 abstract "A perfusion model of global cerebral ischemia was used for the immunohistochemical study of changes in the glutamate-nitric oxide (NO) system in the rat cerebellum and cerebellar nuclei during a 0-14 h reperfusion period after 30 min of oxygen and glucose deprivation, with and without administration of 1.5 mM N(omega)-nitro-L-arginine methyl ester (L-NAME). While immunostaining for N-methyl-D-aspartate receptor subunit 1 (NMDAR1) showed no marked changes during the reperfusion period, neuronal NO synthase (nNOS) immunostaining increased in stellate and basket cells, granule cells and neurons of the cerebellar nuclei. However, global cerebellar nNOS concentrations determined by Western blotting remained largely unchanged in comparison with actin expression. Inducible NOS (iNOS) immunostaining appeared in Purkinje cells and neurons of the cerebellar nuclei after 2-4 h of reperfusion and intensified during the 6-14 h period. This was reflected by an increase in global cerebellar iNOS expression determined by Western blotting. Immunostaining for protein nitrotyrosine was seen in Purkinje cells, stellate and basket cells, neurons of the cerebellar nuclei and glial cells in controls, and showed a progressive translocation in Purkinje cells and neurons of the cerebellar nuclei from an initial perinuclear or nuclear location towards the periphery. At the end of the reperfusion period the Purkinje cell apical dendrites were notably retracted and tortuous. Prior and concurrent L-NAME administration eliminated nitrotyrosine immunostaining in controls and blocked or reduced most of the postischemic changes observed. The results suggest that while nNOS expression may be modified in certain cells, iNOS is induced after a 2-4 h period, and that changes in protein nitration may be associated with changes in cell morphology." @default.
• W2018879423 created "2016-06-24" @default.
• W2018879423 creator A5002065879 @default.
• W2018879423 creator A5022748570 @default.
• W2018879423 creator A5035833740 @default.
• W2018879423 creator A5053219049 @default.
• W2018879423 creator A5061878808 @default.
• W2018879423 creator A5070873233 @default.
• W2018879423 creator A5070914067 @default.
• W2018879423 creator A5072240162 @default.
• W2018879423 creator A5074821680 @default.
• W2018879423 creator A5078445284 @default.
• W2018879423 creator A5083212536 @default.
• W2018879423 date "2001-08-01" @default.
• W2018879423 modified "2023-09-30" @default.
• W2018879423 title "Neuronal and inducible nitric oxide synthase expression and protein nitration in rat cerebellum after oxygen and glucose deprivation" @default.
• W2018879423 cites W133907179 @default.
• W2018879423 cites W1483990664 @default.
• W2018879423 cites W1513132249 @default.
• W2018879423 cites W1608961846 @default.
• W2018879423 cites W1662308449 @default.
• W2018879423 cites W1667686291 @default.
• W2018879423 cites W175616894 @default.
• W2018879423 cites W1764308599 @default.
• W2018879423 cites W1821918060 @default.
• W2018879423 cites W1963751845 @default.
• W2018879423 cites W1964776414 @default.
• W2018879423 cites W1966322594 @default.
• W2018879423 cites W1970331506 @default.
• W2018879423 cites W1975941571 @default.
• W2018879423 cites W1977597523 @default.
• W2018879423 cites W1978969417 @default.
• W2018879423 cites W1980021607 @default.
• W2018879423 cites W1983513923 @default.
• W2018879423 cites W1985249648 @default.
• W2018879423 cites W1985597071 @default.
• W2018879423 cites W1991680851 @default.
• W2018879423 cites W1994306864 @default.
• W2018879423 cites W1994638214 @default.
• W2018879423 cites W1998516209 @default.
• W2018879423 cites W1998831477 @default.
• W2018879423 cites W2000886554 @default.
• W2018879423 cites W2007164137 @default.
• W2018879423 cites W2007354513 @default.
• W2018879423 cites W2010548443 @default.
• W2018879423 cites W2011095668 @default.
• W2018879423 cites W2011318716 @default.
• W2018879423 cites W2017329375 @default.
• W2018879423 cites W2024862570 @default.
• W2018879423 cites W2026371618 @default.
• W2018879423 cites W2032469975 @default.
• W2018879423 cites W2034623336 @default.
• W2018879423 cites W2038611648 @default.
• W2018879423 cites W2039816457 @default.
• W2018879423 cites W2042782418 @default.
• W2018879423 cites W2047843548 @default.
• W2018879423 cites W2048635427 @default.
• W2018879423 cites W2048861892 @default.
• W2018879423 cites W2052103657 @default.
• W2018879423 cites W2056656812 @default.
• W2018879423 cites W2058086138 @default.
• W2018879423 cites W2058193589 @default.
• W2018879423 cites W2059368708 @default.
• W2018879423 cites W2059640915 @default.
• W2018879423 cites W2062483277 @default.
• W2018879423 cites W2071553665 @default.
• W2018879423 cites W2074187719 @default.
• W2018879423 cites W2076353960 @default.
• W2018879423 cites W2082422982 @default.
• W2018879423 cites W2085012999 @default.
• W2018879423 cites W2087048915 @default.
• W2018879423 cites W2087317810 @default.
• W2018879423 cites W2088683988 @default.
• W2018879423 cites W2090953577 @default.
• W2018879423 cites W2094038408 @default.
• W2018879423 cites W2096428903 @default.
• W2018879423 cites W2096505980 @default.
• W2018879423 cites W2099226007 @default.
• W2018879423 cites W2099649534 @default.
• W2018879423 cites W2106985452 @default.
• W2018879423 cites W2112736947 @default.
• W2018879423 cites W2116500181 @default.
• W2018879423 cites W2140936548 @default.
• W2018879423 cites W2142575579 @default.
• W2018879423 cites W2151866626 @default.
• W2018879423 cites W2167207140 @default.
• W2018879423 cites W2172252610 @default.
• W2018879423 cites W2174668858 @default.
• W2018879423 cites W2233442072 @default.
• W2018879423 cites W2419177611 @default.
• W2018879423 cites W266349836 @default.
• W2018879423 cites W4214868137 @default.
• W2018879423 cites W4246812219 @default.
• W2018879423 cites W4256039077 @default.
• W2018879423 cites W4293247451 @default.
• W2018879423 cites W4313323083 @default.
• W2018879423 doi "https://doi.org/10.1016/s0006-8993(01)02613-0" @default.
• W2018879423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11478918" @default.

• next