FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018927502> ?p ?o ?g. }

• W2018927502 endingPage "53" @default.
• W2018927502 startingPage "41" @default.
• W2018927502 abstract "Base usage and dinucleotide frequency have been extensively studied in many eukaryotic organisms and bacteria, but not for viruses. In this paper, a comprehensive analysis of these aspects for infectious bursal disease virus (IBDV) was presented. The analysis of base usage indicated that all of the IBDV genes possess equivalent overall nucleotide distributions. However when the base usage at each codon positions was analysed by using cluster analysis, the VP5 open reading frame (ORF) formed a different cluster isolated from the other genes. The unusual base usage of VP5 ORF may indicate that the gene was originated by the virus overprinting strategy, a strategy in which virus may create novel gene by utilizing the unused reading frames of its existing genes. Meanwhile, the GC content of the IBDV genes and the chicken's coding sequences was comparable; suggesting the virus imitation of the host to increase its translational efficiency. The analysis of dinucleotide frequency indicated that IBDV genome had dinucleotide bias: the frequencies of CpG and TpA were lower and the TpG was higher than the expected. Classical methylation pathway, a process where CpG converted to TpG, may explain the significant correlation between the CpG deficiency and TpG abundance. Principal component analysis of the dinucleotide frequencies (DF-PCA) was used to analyse the overall dinucleotide frequencies of IBDV genome. DF-PCA on the hypervariable region and polyprotein (VPX-VP4-VP3) gene showed that the very virulent IBDV (vvIBDV) was segregated from other strains; which meant vvIBDV had a unique dinucleotide pattern. In summary, the study of base usage and dinucleotide frequency had unravelled many overlooked genomic properties of the virus." @default.
• W2018927502 created "2016-06-24" @default.
• W2018927502 creator A5018023002 @default.
• W2018927502 creator A5025018008 @default.
• W2018927502 creator A5032503573 @default.
• W2018927502 creator A5048667665 @default.
• W2018927502 creator A5048949487 @default.
• W2018927502 date "2004-01-01" @default.
• W2018927502 modified "2023-10-06" @default.
• W2018927502 title "Base Usage and Dinucleotide Frequency of Infectious Bursal Disease Virus" @default.
• W2018927502 cites W1512397531 @default.
• W2018927502 cites W1561119367 @default.
• W2018927502 cites W1573659512 @default.
• W2018927502 cites W1597842671 @default.
• W2018927502 cites W1628781333 @default.
• W2018927502 cites W1644577573 @default.
• W2018927502 cites W165020585 @default.
• W2018927502 cites W1929212571 @default.
• W2018927502 cites W193446248 @default.
• W2018927502 cites W1964360556 @default.
• W2018927502 cites W1969474212 @default.
• W2018927502 cites W1974417513 @default.
• W2018927502 cites W1975292664 @default.
• W2018927502 cites W1977413695 @default.
• W2018927502 cites W1978543157 @default.
• W2018927502 cites W1978934437 @default.
• W2018927502 cites W1979399804 @default.
• W2018927502 cites W1981747163 @default.
• W2018927502 cites W1981996288 @default.
• W2018927502 cites W1999096812 @default.
• W2018927502 cites W2009095852 @default.
• W2018927502 cites W2014247537 @default.
• W2018927502 cites W2017504860 @default.
• W2018927502 cites W2033771774 @default.
• W2018927502 cites W2034105248 @default.
• W2018927502 cites W2042809849 @default.
• W2018927502 cites W2042835129 @default.
• W2018927502 cites W2043819807 @default.
• W2018927502 cites W2043915120 @default.
• W2018927502 cites W2044719651 @default.
• W2018927502 cites W2045954345 @default.
• W2018927502 cites W2047925932 @default.
• W2018927502 cites W2048841761 @default.
• W2018927502 cites W2050492814 @default.
• W2018927502 cites W2059345033 @default.
• W2018927502 cites W2061950855 @default.
• W2018927502 cites W2063046740 @default.
• W2018927502 cites W2065074720 @default.
• W2018927502 cites W2069485883 @default.
• W2018927502 cites W2070184351 @default.
• W2018927502 cites W2073784381 @default.
• W2018927502 cites W2078919721 @default.
• W2018927502 cites W2082736531 @default.
• W2018927502 cites W2086015895 @default.
• W2018927502 cites W2087034526 @default.
• W2018927502 cites W2087525107 @default.
• W2018927502 cites W2088156872 @default.
• W2018927502 cites W2092145460 @default.
• W2018927502 cites W2094055118 @default.
• W2018927502 cites W2094654055 @default.
• W2018927502 cites W2097382368 @default.
• W2018927502 cites W2099619575 @default.
• W2018927502 cites W2100352133 @default.
• W2018927502 cites W2102053035 @default.
• W2018927502 cites W2107187291 @default.
• W2018927502 cites W2109326893 @default.
• W2018927502 cites W2110342329 @default.
• W2018927502 cites W2111785979 @default.
• W2018927502 cites W2116367193 @default.
• W2018927502 cites W2127501111 @default.
• W2018927502 cites W2127587098 @default.
• W2018927502 cites W2128333688 @default.
• W2018927502 cites W2131254312 @default.
• W2018927502 cites W2131339487 @default.
• W2018927502 cites W2137320144 @default.
• W2018927502 cites W2140211206 @default.
• W2018927502 cites W2140798543 @default.
• W2018927502 cites W2144679271 @default.
• W2018927502 cites W2146397496 @default.
• W2018927502 cites W2157694742 @default.
• W2018927502 cites W2161167739 @default.
• W2018927502 cites W2165442408 @default.
• W2018927502 cites W2167338408 @default.
• W2018927502 cites W2182071854 @default.
• W2018927502 cites W2317795005 @default.
• W2018927502 cites W2322041827 @default.
• W2018927502 cites W308579143 @default.
• W2018927502 cites W49443057 @default.
• W2018927502 doi "https://doi.org/10.1023/b:viru.0000012262.89898.c7" @default.
• W2018927502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7089146" @default.
• W2018927502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14739650" @default.
• W2018927502 hasPublicationYear "2004" @default.
• W2018927502 type Work @default.
• W2018927502 sameAs 2018927502 @default.
• W2018927502 citedByCount "13" @default.
• W2018927502 countsByYear W20189275022013 @default.
• W2018927502 countsByYear W20189275022014 @default.
• W2018927502 countsByYear W20189275022018 @default.

• next