FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018931350> ?p ?o ?g. }

• W2018931350 endingPage "1242" @default.
• W2018931350 startingPage "1237" @default.
• W2018931350 abstract "Thyroid autoantibody synthesis was investigated in cultures of lymphocytes isolated from several sources, including thyroid and lymph nodes from patients with hyperthyroid Graves' disease treated preoperatively with carbimazole or propranolol. The ability of thyroid lymphocytes to secrete immunoglobulins, including thyroid microsomal or thyroglobulin autoantibodies, was markedly reduced in lymphocyte suspensions obtained from patients treated with carbimazole compared with suspensions from patients treated with propranolol. This effect (which was greater in individuals treated with carbimazole for longer periods) was attributable to a significant reduction in the number of viable lymphocytes present after the 14-day culture interval. In contrast, the type of preoperative therapy had little effect on cultures of lymphocytes obtained from lymph nodes draining the thyroid. Although it is not yet clear whether carbimazole exerts its effects in vivo by direct immunosuppression or indirectly by altering the thyroid microenvironment, our observations indicate that the fall in serum levels of thyroid autoantibodies that occurs during carbimazole therapy is related to an effect of the drug on lymphocytes within the thyroid." @default.
• W2018931350 created "2016-06-24" @default.
• W2018931350 creator A5007832684 @default.
• W2018931350 creator A5013164815 @default.
• W2018931350 creator A5018820715 @default.
• W2018931350 creator A5032379780 @default.
• W2018931350 creator A5048792432 @default.
• W2018931350 creator A5055004417 @default.
• W2018931350 creator A5056034806 @default.
• W2018931350 date "1985-06-01" @default.
• W2018931350 modified "2023-09-25" @default.
• W2018931350 title "The Effect of Carbimazole on Thyroid Autoantibody Synthesis by Thyroid Lymphocytes*" @default.
• W2018931350 cites W125470952 @default.
• W2018931350 cites W1559445603 @default.
• W2018931350 cites W1963984598 @default.
• W2018931350 cites W1967550328 @default.
• W2018931350 cites W1975973643 @default.
• W2018931350 cites W1988311586 @default.
• W2018931350 cites W1998086464 @default.
• W2018931350 cites W1998508932 @default.
• W2018931350 cites W2009622110 @default.
• W2018931350 cites W2010096083 @default.
• W2018931350 cites W2017702963 @default.
• W2018931350 cites W2024639862 @default.
• W2018931350 cites W2029849007 @default.
• W2018931350 cites W2047646214 @default.
• W2018931350 cites W2048510999 @default.
• W2018931350 cites W2064234766 @default.
• W2018931350 cites W2074797879 @default.
• W2018931350 cites W2084833645 @default.
• W2018931350 cites W2088576787 @default.
• W2018931350 cites W2094843221 @default.
• W2018931350 cites W2146733264 @default.
• W2018931350 cites W2154684656 @default.
• W2018931350 cites W2160418182 @default.
• W2018931350 cites W2337157164 @default.
• W2018931350 cites W2415106997 @default.
• W2018931350 cites W2418570547 @default.
• W2018931350 cites W312311876 @default.
• W2018931350 cites W2270348610 @default.
• W2018931350 doi "https://doi.org/10.1210/jcem-60-6-1237" @default.
• W2018931350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3838998" @default.
• W2018931350 hasPublicationYear "1985" @default.
• W2018931350 type Work @default.
• W2018931350 sameAs 2018931350 @default.
• W2018931350 citedByCount "28" @default.
• W2018931350 countsByYear W20189313502013 @default.
• W2018931350 crossrefType "journal-article" @default.
• W2018931350 hasAuthorship W2018931350A5007832684 @default.
• W2018931350 hasAuthorship W2018931350A5013164815 @default.
• W2018931350 hasAuthorship W2018931350A5018820715 @default.
• W2018931350 hasAuthorship W2018931350A5032379780 @default.
• W2018931350 hasAuthorship W2018931350A5048792432 @default.
• W2018931350 hasAuthorship W2018931350A5055004417 @default.
• W2018931350 hasAuthorship W2018931350A5056034806 @default.
• W2018931350 hasConcept C126322002 @default.
• W2018931350 hasConcept C134018914 @default.
• W2018931350 hasConcept C158479217 @default.
• W2018931350 hasConcept C159654299 @default.
• W2018931350 hasConcept C163764329 @default.
• W2018931350 hasConcept C203014093 @default.
• W2018931350 hasConcept C2776254400 @default.
• W2018931350 hasConcept C2776652619 @default.
• W2018931350 hasConcept C2777761686 @default.
• W2018931350 hasConcept C2778835679 @default.
• W2018931350 hasConcept C2779442721 @default.
• W2018931350 hasConcept C2993291352 @default.
• W2018931350 hasConcept C50181227 @default.
• W2018931350 hasConcept C526584372 @default.
• W2018931350 hasConcept C71924100 @default.
• W2018931350 hasConceptScore W2018931350C126322002 @default.
• W2018931350 hasConceptScore W2018931350C134018914 @default.
• W2018931350 hasConceptScore W2018931350C158479217 @default.
• W2018931350 hasConceptScore W2018931350C159654299 @default.
• W2018931350 hasConceptScore W2018931350C163764329 @default.
• W2018931350 hasConceptScore W2018931350C203014093 @default.
• W2018931350 hasConceptScore W2018931350C2776254400 @default.
• W2018931350 hasConceptScore W2018931350C2776652619 @default.
• W2018931350 hasConceptScore W2018931350C2777761686 @default.
• W2018931350 hasConceptScore W2018931350C2778835679 @default.
• W2018931350 hasConceptScore W2018931350C2779442721 @default.
• W2018931350 hasConceptScore W2018931350C2993291352 @default.
• W2018931350 hasConceptScore W2018931350C50181227 @default.
• W2018931350 hasConceptScore W2018931350C526584372 @default.
• W2018931350 hasConceptScore W2018931350C71924100 @default.
• W2018931350 hasIssue "6" @default.
• W2018931350 hasLocation W20189313501 @default.
• W2018931350 hasLocation W20189313502 @default.
• W2018931350 hasOpenAccess W2018931350 @default.
• W2018931350 hasPrimaryLocation W20189313501 @default.
• W2018931350 hasRelatedWork W125470952 @default.
• W2018931350 hasRelatedWork W161873529 @default.
• W2018931350 hasRelatedWork W183630986 @default.
• W2018931350 hasRelatedWork W2018931350 @default.
• W2018931350 hasRelatedWork W2025713915 @default.
• W2018931350 hasRelatedWork W2064573593 @default.
• W2018931350 hasRelatedWork W2084555174 @default.
• W2018931350 hasRelatedWork W2291658662 @default.

• next