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- W2018935105 abstract "Meeting Abstracts1 May 1972The Standardized Bleeding Time as a Measure of Platelet Function In Vivo.Sherrill J. Slichter, M.D., Laurence A. Harker, M.D.Sherrill J. Slichter, M.D.Search for more papers by this author, Laurence A. Harker, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-76-5-871_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe modified template Ivy bleeding time was evaluated as a test of in vivo platelet function in 79 selected patients with acquired and genetic platelet dysfunction. The bleeding time in 100 normal subjects averaged 4.5 minutes ± 1.7 (± 1 SD). In studies with aspirin, phenylbutazone, paraproteinemia, uremia, and von Willebrand's disease, prolongation of the bleeding time was both a more sensitive and reproducible test than a battery of in vitro function tests that included collagen adhesion; aggregation with adenosine diphosphate, adrenalin, collagen, thrombin; glass bead retention; platelet factor 3 (phospholipid); and clot retraction.In 27 patients with hypoproliferative thrombocytopenia,... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: Sherrill J. Slichter, M.D.; Laurence A. Harker, M.D.Affiliations: Seattle, Wash. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1972Volume 76, Issue 5Page: 871-871KeywordsAdenosine diphosphateAspirinGeneticsHemorrhagePhospholipidsPlateletsThrombinvon Willebrand disease ePublished: 1 December 2008 Issue Published: 1 May 1972 PDF downloadLoading ..." @default.
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- W2018935105 date "1972-05-01" @default.
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- W2018935105 title "The Standardized Bleeding Time as a Measure of Platelet Function In Vivo." @default.
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