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- W2018939881 abstract "Vapor-induced transformations of docetaxel anhydrous (form DA) under ambient conditions have been studied using methanol, ethanol, and water as the solvent media. The online vapor-induced transformations were monitored by powder X-ray diffractometry. New solid forms (solvates/hydrates/anhydrous) of docetaxel anhydrous were obtained in stoichiometric ratios which were characterized completely using powder X-ray diffraction, differential scanning calorimeter, thermogravimetric analysis, and spectroscopic (13C solid-state nuclear magnetic spectroscopy, solution 1H NMR, and Fourier transform infrared) techniques. The new forms namely methanol solvate (DM), ethanol solvate (DE), monohydrate (DMH), trihydrate (DTH), and anhydrous (DAN-I and DAN-II) were identified through structural analysis." @default.
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- W2018939881 date "2012-04-03" @default.
- W2018939881 modified "2023-10-03" @default.
- W2018939881 title "Vapor-Induced Phase Transformations in Docetaxel" @default.
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- W2018939881 doi "https://doi.org/10.1208/s12249-012-9774-7" @default.
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