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- W2018943853 abstract "La paralysie supranucléaire progressive (PSP) est une maladie très rare chez les adultes jeunes, mais elle n’est pas exceptionnelle chez les sujets âgés. Il faut savoir penser à ce diagnostic chez les patients de plus de 60 ans atteints d’un syndrome extrapyramidal résistant à la lévodopa, de troubles cognitifs et/ou de paralysie de la verticalité du regard. Le diagnostic en est principalement clinique, s’appuyant sur une concordance de symptômes, et il peut être conforté par l’IRM et l’oculographie. Il existe fréquemment un retard diagnostique de l’ordre de deux ans pour cette maladie, souvent prise à tort pour une maladie de Parkinson et traitée comme telle. Aucun traitement efficace n’est disponible, à ce jour, pour cette maladie ; ce sont principalement les mesures symptomatiques qui sont utiles. Son pronostic est mauvais : en effet, la survie médiane de ces patients est de l’ordre de dix ans. Progressive supranuclear palsy (PSP) is a very rare disease in young adults, but might be encountered in older adults. PSP diagnosis should be discussed in patients older than 60 years, with extrapyramidal syndrome, which resist to levodopa, cognitive impairment, and/or vertical supranuclear palsy. The diagnosis is mainly done by clinical signs, and can be confirmed by RMI and/or oculography. There is a mean delay of two years to make the diagnosis of this disease, often wrongly diagnosed as Parkinson disease, and treated as if it was. There is no efficient treatment at the moment, but symptomatic therapeutics are usefulness. The prognostic of PSP is bad, and median survival of these patients is about 10 years." @default.
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- W2018943853 date "2011-12-01" @default.
- W2018943853 modified "2023-10-14" @default.
- W2018943853 title "La paralysie supranucléaire progressive : un diagnostic méconnu en gériatrie" @default.
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- W2018943853 doi "https://doi.org/10.1016/j.npg.2011.06.003" @default.
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