FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2018971773> ?p ?o ?g. }

• W2018971773 endingPage "167" @default.
• W2018971773 startingPage "147" @default.
• W2018971773 abstract "Awake dogs were studied before (control) and after chronic bilateral carotid denervation (denervated) at rest and running for 3 min on a treadmill, at 8 km · h−1 and at various grades, in an altitude chamber operated either at 140 m or at 4000 m for 3 h. Steady-state pulmonary ventilation (V̇g) and breathing pattern (VT, fR), oxygen consumption (ṀO2), O2 concentrations (C) pressures (P) in the arterial (a) and mixed venous blood (v), hematocrit (Ht) and acid-base status in arterial blood, and heart frequency (fH) were measured. From these data cardiac output (V̇b) and stroke volume (Vs), ventilatory and circulatory requirements (V̇g/ṀO2, V̇b/ṀO2), extraction of O2 from inspired gas (EairO2) and blood (EbO2), and capacitance coefficient of blood for oxygen (βbO2) were calculated. Ventilatory responses to transient O2-inhalation were also studied and the aortic (AP) and pulmonary (PP) blood pressures measured in resting conditions. 1. After chronic carotid denervation the hypoxic chemoreflex drive of ventilation was reduced by about half, maximal ṀO2 remained unaffected at 140 m, but at 4000 m decreased 50% compared to 30% in controls. 2. In all experimental conditions, V̇g/ṀO2, PaO2 and CaO2 were less in denervated animals than in controls, and EairO2, PaCO2 and H+ ion concentration were higher. 3. At 140 m, circulatory O2 convective transport was identical in the two groups of dogs. At 4000 m, βbO2 increased similarly in both groups, but V̇b and V̇b/ṀO2 were higher in denervated dogs than in controls, in relation with reduced CaO2−CvO2 difference which contributed to restore PvO2 towards higher values. 4. At 140 m, mean resting AP and PP were similar in both groups of dogs. At 4000 m, AP increased not significantly in controls, and decreased in denervated animals; PP increased in controls, but not in denervated dogs. It is concluded that integrity of the arterial chemoreceptor drive is essential in determining the eupneic level of ventilation and normal acid-base status of the blood in both resting and exercising dogs, at low and at high altitude, and in reducing the O2 circulatory requirement at high altitude. At 4000 m, the lack of carotid chemosensitivity is accompanied by severe hypoxemia, in association with hypercapnia and acidosis, and by increased cardiac blood flow, most presumably due to decreased peripheral resistance and increased venous return; despite these compensatory changes in circulatory O2 convective transport, denervated animals reach a maximum O2 uptake at lower work load than controls." @default.
• W2018971773 created "2016-06-24" @default.
• W2018971773 creator A5025334148 @default.
• W2018971773 creator A5031514751 @default.
• W2018971773 creator A5037110151 @default.
• W2018971773 creator A5045263295 @default.
• W2018971773 creator A5046318903 @default.
• W2018971773 date "1981-02-01" @default.
• W2018971773 modified "2023-10-15" @default.
• W2018971773 title "Carotid chemoreceptor function in ventilatory and circulatory O2 convection of exercising dogs at low and high altitude" @default.
• W2018971773 cites W1979445068 @default.
• W2018971773 cites W1981194789 @default.
• W2018971773 cites W2001375290 @default.
• W2018971773 cites W2010296843 @default.
• W2018971773 cites W2012200433 @default.
• W2018971773 cites W2016543724 @default.
• W2018971773 cites W2036914370 @default.
• W2018971773 cites W2060397260 @default.
• W2018971773 cites W2077261778 @default.
• W2018971773 cites W2077792624 @default.
• W2018971773 cites W2084240132 @default.
• W2018971773 cites W2088608664 @default.
• W2018971773 cites W2105558873 @default.
• W2018971773 cites W2140710427 @default.
• W2018971773 cites W2156514486 @default.
• W2018971773 cites W2172825985 @default.
• W2018971773 cites W2180247873 @default.
• W2018971773 cites W2224151316 @default.
• W2018971773 cites W2227507121 @default.
• W2018971773 cites W2230496817 @default.
• W2018971773 cites W2322271915 @default.
• W2018971773 cites W2344056676 @default.
• W2018971773 cites W2414056039 @default.
• W2018971773 cites W2414883939 @default.
• W2018971773 cites W2416796034 @default.
• W2018971773 cites W2466813848 @default.
• W2018971773 doi "https://doi.org/10.1016/0034-5687(81)90006-2" @default.
• W2018971773 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6787682" @default.
• W2018971773 hasPublicationYear "1981" @default.
• W2018971773 type Work @default.
• W2018971773 sameAs 2018971773 @default.
• W2018971773 citedByCount "16" @default.
• W2018971773 countsByYear W20189717732012 @default.
• W2018971773 countsByYear W20189717732014 @default.
• W2018971773 countsByYear W20189717732021 @default.
• W2018971773 crossrefType "journal-article" @default.
• W2018971773 hasAuthorship W2018971773A5025334148 @default.
• W2018971773 hasAuthorship W2018971773A5031514751 @default.
• W2018971773 hasAuthorship W2018971773A5037110151 @default.
• W2018971773 hasAuthorship W2018971773A5045263295 @default.
• W2018971773 hasAuthorship W2018971773A5046318903 @default.
• W2018971773 hasConcept C126322002 @default.
• W2018971773 hasConcept C127413603 @default.
• W2018971773 hasConcept C139940330 @default.
• W2018971773 hasConcept C164705383 @default.
• W2018971773 hasConcept C178853913 @default.
• W2018971773 hasConcept C185592680 @default.
• W2018971773 hasConcept C200457457 @default.
• W2018971773 hasConcept C2777257755 @default.
• W2018971773 hasConcept C2777953023 @default.
• W2018971773 hasConcept C2779537118 @default.
• W2018971773 hasConcept C2780959883 @default.
• W2018971773 hasConcept C42219234 @default.
• W2018971773 hasConcept C534529494 @default.
• W2018971773 hasConcept C71924100 @default.
• W2018971773 hasConcept C72859922 @default.
• W2018971773 hasConcept C78519656 @default.
• W2018971773 hasConcept C80461066 @default.
• W2018971773 hasConcept C84393581 @default.
• W2018971773 hasConceptScore W2018971773C126322002 @default.
• W2018971773 hasConceptScore W2018971773C127413603 @default.
• W2018971773 hasConceptScore W2018971773C139940330 @default.
• W2018971773 hasConceptScore W2018971773C164705383 @default.
• W2018971773 hasConceptScore W2018971773C178853913 @default.
• W2018971773 hasConceptScore W2018971773C185592680 @default.
• W2018971773 hasConceptScore W2018971773C200457457 @default.
• W2018971773 hasConceptScore W2018971773C2777257755 @default.
• W2018971773 hasConceptScore W2018971773C2777953023 @default.
• W2018971773 hasConceptScore W2018971773C2779537118 @default.
• W2018971773 hasConceptScore W2018971773C2780959883 @default.
• W2018971773 hasConceptScore W2018971773C42219234 @default.
• W2018971773 hasConceptScore W2018971773C534529494 @default.
• W2018971773 hasConceptScore W2018971773C71924100 @default.
• W2018971773 hasConceptScore W2018971773C72859922 @default.
• W2018971773 hasConceptScore W2018971773C78519656 @default.
• W2018971773 hasConceptScore W2018971773C80461066 @default.
• W2018971773 hasConceptScore W2018971773C84393581 @default.
• W2018971773 hasIssue "2" @default.
• W2018971773 hasLocation W20189717731 @default.
• W2018971773 hasLocation W20189717732 @default.
• W2018971773 hasOpenAccess W2018971773 @default.
• W2018971773 hasPrimaryLocation W20189717731 @default.
• W2018971773 hasRelatedWork W1998168842 @default.
• W2018971773 hasRelatedWork W2014129240 @default.
• W2018971773 hasRelatedWork W2019424709 @default.
• W2018971773 hasRelatedWork W2054060818 @default.
• W2018971773 hasRelatedWork W2106083255 @default.
• W2018971773 hasRelatedWork W2395601063 @default.

• next