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- W2018980212 abstract "1. The ionic response of the liver fluke, Fasciola hepatica to perturbation of Na,K-pump activity has been determined by atomic absorption spectrophotometry. 2. The Na+/K+-ATPase inhibitor ouabain (1 × 10−4M) induced a marked reduction in K+ levels; Na+ and Ca2+ levels also fell. 3. The sodium ionophore monensin (1 × 10−4M) also caused a decrease in K+ levels, to below that of Na+. 4. Brief pretreatment with ouabain (1 × 10−4 M, 15 min) followed by monensin treatment did not affect the decline in K+ levels, but did prevent the short-lived Na+ decline observed with monensin alone. 5. The deacetylated (amine) metabolite of the fasciolicide diamphenethide caused a short-lived drop in Na+ levels, but otherwise produced little change in ion levels within the fluke." @default.
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- W2018980212 date "1991-01-01" @default.
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- W2018980212 title "The ionic response of the liver fluke, Fasciola hepatica to ouabain, monensin and the deacetylated (amine) metabolite of diamphenethide" @default.
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- W2018980212 doi "https://doi.org/10.1016/0300-9629(91)90305-v" @default.
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