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- W2018988882 abstract "Transposition of Great Vessels (TGV) occurs when there is an abnormality in the development of the conotruncal septum of the fetal heart and can lead to significant neonatal morbidity. Cases of TGV diagnosed in KK Women's and Children's Hospital were reviewed to determine the incidence of the condition, detection rate of antenatal sonography for the diagnosis of TGV and the postnatal outcomes of these cases. This study included all cases of antenatally diagnosed TGV from the hospital based Birth Defect Registry. In addition, records of TGV cases from the Paediatric Cardiology Department and Paediatric Cardiothoracic Surgery Department were also reviewed. In the period from 1st January 1996 to 31st December 2003, there were 31 cases of diagnosed TGV cases among 124 931 deliveries, resulting in an incidence rate of 1 in 4031. Routine antenatal fetal echocardiography with outflow tract examination diagnosed 25 cases antenatally, leading to a detection rate of 80.6% for the diagnosis of TGV cases. 5 pregnancies were terminated after the parents were counselled about the possible postnatal outcome. Postnatally, 19 cases underwent definitive corrective surgery with the arterial switch surgery. The remaining cases underwent palliative systemic-pulmonary shunt procedures. In this cohort of cases, there was 1 case of post-surgical mortality. TGV is a congenital cardiac abnormality that can be detected on antenatal fetal echocardiography with examination of the outflow tracts with a high sensitivity rate. With a definitive diagnosis, corrective surgery with low mortality rates is feasible." @default.
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- W2018988882 date "2004-08-01" @default.
- W2018988882 modified "2023-09-23" @default.
- W2018988882 title "P01.17: Transposition of great vessels-a single centre review in an Asian population" @default.
- W2018988882 doi "https://doi.org/10.1002/uog.1323" @default.
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