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- W2018993752 abstract "The necessity of maintaining a patient with “free” aortic regurgitation on an electrical pacemaker for several days permitted some observations of the effect of heart rate in this disorder. At rates below 90 per minute, stroke volume apparently did not maintain minute cardiac output. Peripheral vasoconstriction maintained mean blood pressure until the heart rate reached 68 beats per minute. Below this level, pulse pressure and mean blood pressure declined steadily. Even at higher heart rates, renal function as measured by renal plasma flow, glomerular filtration and urine and electrolyte excretion were very sensitive indicators of the decline of blood flow as the heart rate was reduced in small decrements. It is concluded that a relatively rapid heart rate can be advantageous in aortic insufficiency with heart failure." @default.
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- W2018993752 title "Some observations on the effect of heart rate controlled by an external stimulator in aortic insufficiency" @default.
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- W2018993752 doi "https://doi.org/10.1016/0002-9343(57)90103-1" @default.
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