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• W2018994672 abstract "Luman (also known as LZIP and CREB3) is a basic leucine zipper transcription factor of the cAMP response element-binding protein/activating transcription factor gene family. Although Luman had specific roles near termination of Drosophila embryogenesis, the physiological functions of Luman in female mammals have apparently not been reported. Therefore, our objective was to investigate the spatiotemporal expression and regulation of Luman in the mouse uterus during the peri-implantation period. Luman protein was clearly present in the luminal and glandular epithelium on days 1 to 4 of pregnancy (day 1, presence of a vaginal plug) and was observed in decidual cells on day 6 of pregnancy. Expression had progressively increased to day 7 when the second decidual zone was formed. On day 8, apoptosis of the decidualized cells was present, and Luman protein expression was decreased (in close association with decidualization). Luman protein was also present in decidual cells of the artificially decidualized uterus. The expression of Luman was regulated by an activated embryo (according to its expression patterns during pseudopregnancy and delayed implantation). Furthermore, expression of Luman was induced by estrogen in ovariectomized mice. We have concluded that Luman might have important roles in embryo implantation and decidualization." @default.
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• W2018994672 date "2013-07-01" @default.
• W2018994672 modified "2023-10-18" @default.
• W2018994672 title "Expression and localization of Luman RNA and protein during mouse implantation and decidualization" @default.
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• W2018994672 doi "https://doi.org/10.1016/j.theriogenology.2013.02.024" @default.
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