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- W2018995185 abstract "1 . Drugs of the morphine type cause a stereotyped “running fit” in the mouse. 2 . The intensity and duration of this response are related to the dose. 3 . Measurement of this phenomenon serves as a good method for the quantitative comparison of drugs of this type and for the study of their antagonists. 4 . Intracerebral injection of physostigmine antagonized the “running fit” induced by a wide range of doses of levorphanol. 5 . The results are consistent with the hypothesis that drugs of the morphine type act by retarding the release of acetylcholine at some central cholinergic synapses." @default.
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- W2018995185 date "1969-09-01" @default.
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- W2018995185 title "Antagonism by physostigmine of the “running fit” caused by levorphanol, a morphine congener, in mice" @default.
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- W2018995185 doi "https://doi.org/10.1111/j.1476-5381.1969.tb09529.x" @default.
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