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• W2018996889 abstract "Purpose To investigate the characteristics of fundus autofluorescence in birdshot chorioretinopathy (BSCR). Design Retrospective, observational case series. Participants Sixteen eyes of 8 consecutive patients with BSCR (3 men, 5 women). Methods Color and autofluorescence photography and optical coherence tomograms of patients with BSCR seen in a referral practice were evaluated. Main Outcome Measures Autofluorescent characteristics in BSCR. Results The 8 patients ranged in age from 35 to 73 years (mean, 56.9 years). Of the 16 eyes, 11 eyes (69%) of 6 patients had retinal pigment epithelium (RPE) atrophy as evidenced by hypoautofluorescent regions. Some of the hypoautofluorescent areas corresponded to the hypopigmented birdshot lesions, but the others did not necessarily show a correspondence. Eight eyes (50%) of 4 patients showed linear hypoautofluorescent streaks along the retinal vessels, most of which corresponded to visible changes at the level of the RPE. Placoid hypoautofluorescence in the macula was seen in 6 eyes (38%) of 3 patients and was correlated significantly with best-corrected visual acuity of 20/50 or less (P<0.05). Conclusions Autofluorescence photography demonstrated the RPE atrophy, which was hard to see by other means of investigation. The areas of RPE atrophy did not necessarily correspond to the hypopigmented lesions, which suggested that both the choroid and the RPE can be affected independently. Retinal pigment epithelium atrophy in the macula may be an important cause of poor central visual acuity in eyes with BSCR. To investigate the characteristics of fundus autofluorescence in birdshot chorioretinopathy (BSCR). Retrospective, observational case series. Sixteen eyes of 8 consecutive patients with BSCR (3 men, 5 women). Color and autofluorescence photography and optical coherence tomograms of patients with BSCR seen in a referral practice were evaluated. Autofluorescent characteristics in BSCR. The 8 patients ranged in age from 35 to 73 years (mean, 56.9 years). Of the 16 eyes, 11 eyes (69%) of 6 patients had retinal pigment epithelium (RPE) atrophy as evidenced by hypoautofluorescent regions. Some of the hypoautofluorescent areas corresponded to the hypopigmented birdshot lesions, but the others did not necessarily show a correspondence. Eight eyes (50%) of 4 patients showed linear hypoautofluorescent streaks along the retinal vessels, most of which corresponded to visible changes at the level of the RPE. Placoid hypoautofluorescence in the macula was seen in 6 eyes (38%) of 3 patients and was correlated significantly with best-corrected visual acuity of 20/50 or less (P<0.05). Autofluorescence photography demonstrated the RPE atrophy, which was hard to see by other means of investigation. The areas of RPE atrophy did not necessarily correspond to the hypopigmented lesions, which suggested that both the choroid and the RPE can be affected independently. Retinal pigment epithelium atrophy in the macula may be an important cause of poor central visual acuity in eyes with BSCR." @default.
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• W2018996889 title "Fundus Autofluorescence in Birdshot Chorioretinopathy" @default.
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• W2018996889 doi "https://doi.org/10.1016/j.ophtha.2008.01.025" @default.
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