Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019015469> ?p ?o ?g. }
- W2019015469 endingPage "272" @default.
- W2019015469 startingPage "261" @default.
- W2019015469 abstract "Vertebrate gap junctions, composed of proteins from the connexin gene family, play critical roles in embryonic development, co-ordinated contraction of excitable cells, tissue homoeostasis, normal cell growth and differentiation. Phosphorylation of connexin43, the most abundant and ubiquitously expressed connexin, has been implicated in the regulation of gap junctional communication at several stages of the connexin 'life cycle', including hemichannel oligomerization, export of the protein to the plasma membrane, hemichannel activity, gap junction assembly, gap junction channel gating and connexin degradation. Consistent with a short (1-5 h) protein half-life, connexin43 phosphorylation is dynamic and changes in response to activation of many different kinases. The present review assesses our current understanding of the effects of phosphorylation on connexin43 structure and function that in turn regulate gap junction biology, with an emphasis on events occurring in heart and skin." @default.
- W2019015469 created "2016-06-24" @default.
- W2019015469 creator A5001784443 @default.
- W2019015469 creator A5028155825 @default.
- W2019015469 date "2009-03-27" @default.
- W2019015469 modified "2023-10-10" @default.
- W2019015469 title "Connexin43 phosphorylation: structural changes and biological effects" @default.
- W2019015469 cites W168312515 @default.
- W2019015469 cites W1822100304 @default.
- W2019015469 cites W1950518418 @default.
- W2019015469 cites W1963739837 @default.
- W2019015469 cites W1964839077 @default.
- W2019015469 cites W1964979152 @default.
- W2019015469 cites W1965028277 @default.
- W2019015469 cites W1969183124 @default.
- W2019015469 cites W1970105142 @default.
- W2019015469 cites W1971256758 @default.
- W2019015469 cites W1972596057 @default.
- W2019015469 cites W1975169487 @default.
- W2019015469 cites W1976613690 @default.
- W2019015469 cites W1979946797 @default.
- W2019015469 cites W1980175578 @default.
- W2019015469 cites W1982019393 @default.
- W2019015469 cites W1982233898 @default.
- W2019015469 cites W1983460238 @default.
- W2019015469 cites W1983983350 @default.
- W2019015469 cites W1984062833 @default.
- W2019015469 cites W1984473048 @default.
- W2019015469 cites W1987594610 @default.
- W2019015469 cites W1989021197 @default.
- W2019015469 cites W1991001519 @default.
- W2019015469 cites W1991230121 @default.
- W2019015469 cites W1991259792 @default.
- W2019015469 cites W1992509114 @default.
- W2019015469 cites W1993013617 @default.
- W2019015469 cites W1993267826 @default.
- W2019015469 cites W1994525597 @default.
- W2019015469 cites W1995248516 @default.
- W2019015469 cites W1995916371 @default.
- W2019015469 cites W1996272414 @default.
- W2019015469 cites W1997019726 @default.
- W2019015469 cites W2000063742 @default.
- W2019015469 cites W2000440135 @default.
- W2019015469 cites W2000846391 @default.
- W2019015469 cites W2001407497 @default.
- W2019015469 cites W2001535568 @default.
- W2019015469 cites W2001718347 @default.
- W2019015469 cites W2004570244 @default.
- W2019015469 cites W2004652628 @default.
- W2019015469 cites W2008465642 @default.
- W2019015469 cites W2010153640 @default.
- W2019015469 cites W2013293055 @default.
- W2019015469 cites W2016324935 @default.
- W2019015469 cites W2017375178 @default.
- W2019015469 cites W2017688904 @default.
- W2019015469 cites W2017907028 @default.
- W2019015469 cites W2019946556 @default.
- W2019015469 cites W2021393627 @default.
- W2019015469 cites W2022135851 @default.
- W2019015469 cites W2023363592 @default.
- W2019015469 cites W2023443037 @default.
- W2019015469 cites W2023953423 @default.
- W2019015469 cites W2027379276 @default.
- W2019015469 cites W2030059917 @default.
- W2019015469 cites W2031713075 @default.
- W2019015469 cites W2033215167 @default.
- W2019015469 cites W2033341081 @default.
- W2019015469 cites W2035095238 @default.
- W2019015469 cites W2035830214 @default.
- W2019015469 cites W2037861220 @default.
- W2019015469 cites W2039058963 @default.
- W2019015469 cites W2039606117 @default.
- W2019015469 cites W2040177382 @default.
- W2019015469 cites W2042964945 @default.
- W2019015469 cites W2045473712 @default.
- W2019015469 cites W2047827091 @default.
- W2019015469 cites W2048807884 @default.
- W2019015469 cites W2049832496 @default.
- W2019015469 cites W2051273609 @default.
- W2019015469 cites W2052311383 @default.
- W2019015469 cites W2052446388 @default.
- W2019015469 cites W2054343568 @default.
- W2019015469 cites W2056590743 @default.
- W2019015469 cites W2056848617 @default.
- W2019015469 cites W2058276854 @default.
- W2019015469 cites W2061671071 @default.
- W2019015469 cites W2063549408 @default.
- W2019015469 cites W2064315055 @default.
- W2019015469 cites W2064467597 @default.
- W2019015469 cites W2065310701 @default.
- W2019015469 cites W2065849653 @default.
- W2019015469 cites W2067072307 @default.
- W2019015469 cites W2067796383 @default.
- W2019015469 cites W2068007378 @default.
- W2019015469 cites W2068472293 @default.
- W2019015469 cites W2070642018 @default.
- W2019015469 cites W2072011163 @default.
- W2019015469 cites W2072564164 @default.