FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019050299> ?p ?o ?g. }

• W2019050299 endingPage "3" @default.
• W2019050299 startingPage "3" @default.
• W2019050299 abstract "Purpose:: To determine if transplantation of olfactory ensheathing cells (OECs) can reduce loss of optic nerve axons after raised intraocular pressure (IOP) in the rat. Methods:: OECs cultured from the adult olfactory mucosa were transplanted into the region of the optic disc. The IOP was raised by injection of magnetic microspheres into the anterior chamber. Results:: At 4 weeks after raising the IOP, the transplanted OECs had migrated into the dorsal area of the optic nerve head (ONH) where they surrounded the optic nerve fibers with a non-myelinated ensheathment. The mean amount of damage to the ONH astrocytic area in rats was 51.0% compared with 85.8% in those without OEC transplants (P < 0.02) and the mean loss of axons in the optic nerve was 51.0% compared with 80.3% in the absence of OECs (P < 0.01). Conclusions:: OECs transplanted into the region of the ONH of the rat can reduce the loss of axons and the damage to ONH astrocytes caused by raised IOP. Translational Relevance:: Confirmation of these preliminary experimental data, further understanding of possible mechanisms of axonal protection by OECs, and the longer-term time course of protection could provide a basis for future human clinical trials of autografted OECs, which would be available from autologous nasal epithelial biopsies." @default.
• W2019050299 created "2016-06-24" @default.
• W2019050299 creator A5017991749 @default.
• W2019050299 creator A5025329094 @default.
• W2019050299 creator A5032372878 @default.
• W2019050299 creator A5060002817 @default.
• W2019050299 creator A5069175872 @default.
• W2019050299 creator A5082134776 @default.
• W2019050299 date "2012-09-01" @default.
• W2019050299 modified "2023-09-27" @default.
• W2019050299 title "Olfactory Ensheathing Cells Rescue Optic Nerve Fibers in a Rat Glaucoma Model" @default.
• W2019050299 cites W1479957045 @default.
• W2019050299 cites W1529601180 @default.
• W2019050299 cites W1657897383 @default.
• W2019050299 cites W1768004330 @default.
• W2019050299 cites W1964003114 @default.
• W2019050299 cites W1977938662 @default.
• W2019050299 cites W1982196248 @default.
• W2019050299 cites W1983601261 @default.
• W2019050299 cites W1983919643 @default.
• W2019050299 cites W1983934079 @default.
• W2019050299 cites W1983945545 @default.
• W2019050299 cites W1985794479 @default.
• W2019050299 cites W1988467528 @default.
• W2019050299 cites W1993918206 @default.
• W2019050299 cites W1996231780 @default.
• W2019050299 cites W2002857052 @default.
• W2019050299 cites W2003351124 @default.
• W2019050299 cites W2009761723 @default.
• W2019050299 cites W2013061553 @default.
• W2019050299 cites W2022805799 @default.
• W2019050299 cites W2027524436 @default.
• W2019050299 cites W2027880899 @default.
• W2019050299 cites W2032370326 @default.
• W2019050299 cites W2047730770 @default.
• W2019050299 cites W2049027234 @default.
• W2019050299 cites W2050232773 @default.
• W2019050299 cites W2054490530 @default.
• W2019050299 cites W2079224601 @default.
• W2019050299 cites W2083672927 @default.
• W2019050299 cites W2087237431 @default.
• W2019050299 cites W2098685543 @default.
• W2019050299 cites W2124427604 @default.
• W2019050299 cites W2130105499 @default.
• W2019050299 cites W2139082112 @default.
• W2019050299 cites W2139155172 @default.
• W2019050299 cites W2140594570 @default.
• W2019050299 cites W2147093603 @default.
• W2019050299 cites W2148511248 @default.
• W2019050299 cites W2150596913 @default.
• W2019050299 cites W2204409130 @default.
• W2019050299 doi "https://doi.org/10.1167/tvst.1.2.3" @default.
• W2019050299 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3763877" @default.
• W2019050299 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24049703" @default.
• W2019050299 hasPublicationYear "2012" @default.
• W2019050299 type Work @default.
• W2019050299 sameAs 2019050299 @default.
• W2019050299 citedByCount "80" @default.
• W2019050299 countsByYear W20190502992012 @default.
• W2019050299 countsByYear W20190502992013 @default.
• W2019050299 countsByYear W20190502992014 @default.
• W2019050299 countsByYear W20190502992015 @default.
• W2019050299 countsByYear W20190502992016 @default.
• W2019050299 countsByYear W20190502992017 @default.
• W2019050299 countsByYear W20190502992018 @default.
• W2019050299 countsByYear W20190502992019 @default.
• W2019050299 countsByYear W20190502992020 @default.
• W2019050299 countsByYear W20190502992021 @default.
• W2019050299 countsByYear W20190502992022 @default.
• W2019050299 countsByYear W20190502992023 @default.
• W2019050299 crossrefType "journal-article" @default.
• W2019050299 hasAuthorship W2019050299A5017991749 @default.
• W2019050299 hasAuthorship W2019050299A5025329094 @default.
• W2019050299 hasAuthorship W2019050299A5032372878 @default.
• W2019050299 hasAuthorship W2019050299A5060002817 @default.
• W2019050299 hasAuthorship W2019050299A5069175872 @default.
• W2019050299 hasAuthorship W2019050299A5082134776 @default.
• W2019050299 hasBestOaLocation W20190502992 @default.
• W2019050299 hasConcept C105702510 @default.
• W2019050299 hasConcept C118487528 @default.
• W2019050299 hasConcept C118552586 @default.
• W2019050299 hasConcept C134018914 @default.
• W2019050299 hasConcept C141071460 @default.
• W2019050299 hasConcept C142724271 @default.
• W2019050299 hasConcept C154988683 @default.
• W2019050299 hasConcept C201792869 @default.
• W2019050299 hasConcept C2778527774 @default.
• W2019050299 hasConcept C2780496858 @default.
• W2019050299 hasConcept C2780837183 @default.
• W2019050299 hasConcept C2781092963 @default.
• W2019050299 hasConcept C2781377823 @default.
• W2019050299 hasConcept C2911091166 @default.
• W2019050299 hasConcept C529278444 @default.
• W2019050299 hasConcept C71924100 @default.
• W2019050299 hasConceptScore W2019050299C105702510 @default.
• W2019050299 hasConceptScore W2019050299C118487528 @default.
• W2019050299 hasConceptScore W2019050299C118552586 @default.
• W2019050299 hasConceptScore W2019050299C134018914 @default.

• next