FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019061641> ?p ?o ?g. }

• W2019061641 endingPage "346" @default.
• W2019061641 startingPage "335" @default.
• W2019061641 abstract "A novel LC–MS-MS assay that simultaneously detects and quantitates 78 drugs and metabolites was developed and validated for chronic pain management. Urine specimen was diluted and mixed with internal standards (ISs) before injected into LC–MS-MS. Seventy-two analytes were detected with positive electrospray ionization mode and the remaining six analytes with negative mode. Two separate gradient elution chromatographic programs were established with the same mobile phases on the same bi-phenyl HPLC column. The assay was linear for all analytes with linear regression coefficient ranging 0.994–1.000. The intra-assay precision was between 1.7 and 8.8% and inter-assay precision between 1.9 and 12.2%, with bias <20% for all but six analytes. All analytes in urine specimens were stable for 7 days at 4°C, and no significant matrix effect or carryover was observed. A suboptimal recovery rate (60.0–156.8%) was observed for six analytes, potentially due to the lack of available deuterated ISs, requiring comparison to a chemically different IS. Method comparison using patient and proficiency testing samples demonstrated that this assay was sensitive and accurate. The assay improves on currently existing assays by including glucuronide conjugates, allowing direct detection of metabolites that might otherwise be missed by existing methods." @default.
• W2019061641 created "2016-06-24" @default.
• W2019061641 creator A5013736647 @default.
• W2019061641 creator A5031366899 @default.
• W2019061641 creator A5045838551 @default.
• W2019061641 date "2015-04-01" @default.
• W2019061641 modified "2023-10-01" @default.
• W2019061641 title "Simultaneous Quantitation of 78 Drugs and Metabolites in Urine with a Dilute-And-Shoot LC–MS-MS Assay" @default.
• W2019061641 cites W1488427122 @default.
• W2019061641 cites W1571289809 @default.
• W2019061641 cites W1964497777 @default.
• W2019061641 cites W1983417139 @default.
• W2019061641 cites W1985347343 @default.
• W2019061641 cites W1991696538 @default.
• W2019061641 cites W2010125810 @default.
• W2019061641 cites W2014786031 @default.
• W2019061641 cites W2016952333 @default.
• W2019061641 cites W2025330700 @default.
• W2019061641 cites W2036081797 @default.
• W2019061641 cites W2038143616 @default.
• W2019061641 cites W2039055030 @default.
• W2019061641 cites W2044783221 @default.
• W2019061641 cites W2082403514 @default.
• W2019061641 cites W2089403728 @default.
• W2019061641 cites W2098201873 @default.
• W2019061641 cites W2104516524 @default.
• W2019061641 cites W2118074811 @default.
• W2019061641 cites W2123061243 @default.
• W2019061641 cites W2140695271 @default.
• W2019061641 cites W2141758025 @default.
• W2019061641 cites W2152439370 @default.
• W2019061641 cites W2155302399 @default.
• W2019061641 cites W2163402540 @default.
• W2019061641 cites W2248152105 @default.
• W2019061641 cites W3137367981 @default.
• W2019061641 cites W2320177008 @default.
• W2019061641 doi "https://doi.org/10.1093/jat/bkv024" @default.
• W2019061641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25833899" @default.
• W2019061641 hasPublicationYear "2015" @default.
• W2019061641 type Work @default.
• W2019061641 sameAs 2019061641 @default.
• W2019061641 citedByCount "40" @default.
• W2019061641 countsByYear W20190616412016 @default.
• W2019061641 countsByYear W20190616412017 @default.
• W2019061641 countsByYear W20190616412018 @default.
• W2019061641 countsByYear W20190616412019 @default.
• W2019061641 countsByYear W20190616412020 @default.
• W2019061641 countsByYear W20190616412021 @default.
• W2019061641 countsByYear W20190616412022 @default.
• W2019061641 countsByYear W20190616412023 @default.
• W2019061641 crossrefType "journal-article" @default.
• W2019061641 hasAuthorship W2019061641A5013736647 @default.
• W2019061641 hasAuthorship W2019061641A5031366899 @default.
• W2019061641 hasAuthorship W2019061641A5045838551 @default.
• W2019061641 hasBestOaLocation W20190616411 @default.
• W2019061641 hasConcept C10390740 @default.
• W2019061641 hasConcept C106487976 @default.
• W2019061641 hasConcept C162356407 @default.
• W2019061641 hasConcept C175467004 @default.
• W2019061641 hasConcept C185592680 @default.
• W2019061641 hasConcept C194451485 @default.
• W2019061641 hasConcept C2780026642 @default.
• W2019061641 hasConcept C40684141 @default.
• W2019061641 hasConcept C43617362 @default.
• W2019061641 hasConcept C55493867 @default.
• W2019061641 hasConcept C64489805 @default.
• W2019061641 hasConcept C89838059 @default.
• W2019061641 hasConceptScore W2019061641C10390740 @default.
• W2019061641 hasConceptScore W2019061641C106487976 @default.
• W2019061641 hasConceptScore W2019061641C162356407 @default.
• W2019061641 hasConceptScore W2019061641C175467004 @default.
• W2019061641 hasConceptScore W2019061641C185592680 @default.
• W2019061641 hasConceptScore W2019061641C194451485 @default.
• W2019061641 hasConceptScore W2019061641C2780026642 @default.
• W2019061641 hasConceptScore W2019061641C40684141 @default.
• W2019061641 hasConceptScore W2019061641C43617362 @default.
• W2019061641 hasConceptScore W2019061641C55493867 @default.
• W2019061641 hasConceptScore W2019061641C64489805 @default.
• W2019061641 hasConceptScore W2019061641C89838059 @default.
• W2019061641 hasIssue "5" @default.
• W2019061641 hasLocation W20190616411 @default.
• W2019061641 hasLocation W20190616412 @default.
• W2019061641 hasOpenAccess W2019061641 @default.
• W2019061641 hasPrimaryLocation W20190616411 @default.
• W2019061641 hasRelatedWork W1609017231 @default.
• W2019061641 hasRelatedWork W1998754189 @default.
• W2019061641 hasRelatedWork W2005572016 @default.
• W2019061641 hasRelatedWork W2006857887 @default.
• W2019061641 hasRelatedWork W2009097369 @default.
• W2019061641 hasRelatedWork W2019061641 @default.
• W2019061641 hasRelatedWork W2057706260 @default.
• W2019061641 hasRelatedWork W2133460187 @default.
• W2019061641 hasRelatedWork W2137594237 @default.
• W2019061641 hasRelatedWork W2525526490 @default.
• W2019061641 hasVolume "39" @default.
• W2019061641 isParatext "false" @default.
• W2019061641 isRetracted "false" @default.
• W2019061641 magId "2019061641" @default.

• next