FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019063404> ?p ?o ?g. }

• W2019063404 endingPage "1383" @default.
• W2019063404 startingPage "1378" @default.
• W2019063404 abstract "Objective: To determine if aging changes the frequency, severity, or manifestations of symptomatic distal sensory polyneuropathy (SxDSPN) in patients with HIV-1. Methods: Prospective observations of 70 older (age ≥ 50) and 56 younger (age 20 to 40) patients with HIV, and a control group of 48 older non-HIV patients, were conducted utilizing neurologic examination, neuropsychological testing, lumbar puncture, laboratory, and medical history. Results: The frequency of SxDSPN among older HIV patients was 50.4%, compared to 19.6% among younger HIV patients ( p < 0.001). SxDSPN among control patients occurred in 4.2%, similar to the general population. Older compared to younger HIV patients demonstrated more severe symptoms ( p = 0.02) and greater deficits for vibration ( p < 0.01). Increasing numbers of neuropathic comorbidities among older compared to younger HIV patients were associated with increasing severity of deficits to pinprick ( p = 0.003). Dementia and SxDSPN coexisted in 36% of the older HIV patients and in none of the younger HIV patients ( p = 0.021). Older HIV patients with nadir CD4 ≤200 cells/mL were 4.23 times as likely to have SxDSPN than older patients with nadir CD4 >200 cells/mL ( p = 0.007). Vibratory deficits excessive to pinprick deficits predicted SxDSPN among older (OR 2.83) but not younger seropositive patients ( p = 0.036). Conclusions: Age ≥50 increases the frequency of SxDSPN, and is associated with both vibratory loss as the predominant sensory deficit and increased severity of pinprick loss among symptomatic patients with neuropathic comorbidities. SxDSPN is associated with both dementia and low nadir CD4 in HIV-positive patients aged 50 and greater." @default.
• W2019063404 created "2016-06-24" @default.
• W2019063404 creator A5016085653 @default.
• W2019063404 creator A5037704558 @default.
• W2019063404 creator A5042381102 @default.
• W2019063404 creator A5047523532 @default.
• W2019063404 creator A5057274213 @default.
• W2019063404 creator A5060291120 @default.
• W2019063404 creator A5072086085 @default.
• W2019063404 date "2004-04-26" @default.
• W2019063404 modified "2023-10-18" @default.
• W2019063404 title "Symptomatic distal sensory polyneuropathy in HIV after age 50" @default.
• W2019063404 cites W1982165255 @default.
• W2019063404 cites W1982793958 @default.
• W2019063404 cites W1994052806 @default.
• W2019063404 cites W2001350842 @default.
• W2019063404 cites W2009318275 @default.
• W2019063404 cites W2039840666 @default.
• W2019063404 cites W2047898375 @default.
• W2019063404 cites W2052769426 @default.
• W2019063404 cites W2059786204 @default.
• W2019063404 cites W2061414782 @default.
• W2019063404 cites W2061747759 @default.
• W2019063404 cites W2078287062 @default.
• W2019063404 cites W2081957638 @default.
• W2019063404 cites W2084092457 @default.
• W2019063404 cites W2101697605 @default.
• W2019063404 cites W2113050200 @default.
• W2019063404 cites W2118621245 @default.
• W2019063404 cites W2119405619 @default.
• W2019063404 cites W2131838224 @default.
• W2019063404 cites W2142672496 @default.
• W2019063404 cites W2144722464 @default.
• W2019063404 cites W2156264261 @default.
• W2019063404 cites W2322798515 @default.
• W2019063404 cites W2612252953 @default.
• W2019063404 cites W2774237554 @default.
• W2019063404 cites W4233782225 @default.
• W2019063404 doi "https://doi.org/10.1212/01.wnl.0000120622.91018.ea" @default.
• W2019063404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15111677" @default.
• W2019063404 hasPublicationYear "2004" @default.
• W2019063404 type Work @default.
• W2019063404 sameAs 2019063404 @default.
• W2019063404 citedByCount "48" @default.
• W2019063404 countsByYear W20190634042012 @default.
• W2019063404 countsByYear W20190634042013 @default.
• W2019063404 countsByYear W20190634042014 @default.
• W2019063404 countsByYear W20190634042015 @default.
• W2019063404 countsByYear W20190634042016 @default.
• W2019063404 countsByYear W20190634042017 @default.
• W2019063404 countsByYear W20190634042019 @default.
• W2019063404 countsByYear W20190634042020 @default.
• W2019063404 countsByYear W20190634042022 @default.
• W2019063404 crossrefType "journal-article" @default.
• W2019063404 hasAuthorship W2019063404A5016085653 @default.
• W2019063404 hasAuthorship W2019063404A5037704558 @default.
• W2019063404 hasAuthorship W2019063404A5042381102 @default.
• W2019063404 hasAuthorship W2019063404A5047523532 @default.
• W2019063404 hasAuthorship W2019063404A5057274213 @default.
• W2019063404 hasAuthorship W2019063404A5060291120 @default.
• W2019063404 hasAuthorship W2019063404A5072086085 @default.
• W2019063404 hasConcept C126322002 @default.
• W2019063404 hasConcept C141071460 @default.
• W2019063404 hasConcept C187212893 @default.
• W2019063404 hasConcept C188816634 @default.
• W2019063404 hasConcept C2775892965 @default.
• W2019063404 hasConcept C2908647359 @default.
• W2019063404 hasConcept C71924100 @default.
• W2019063404 hasConcept C99454951 @default.
• W2019063404 hasConceptScore W2019063404C126322002 @default.
• W2019063404 hasConceptScore W2019063404C141071460 @default.
• W2019063404 hasConceptScore W2019063404C187212893 @default.
• W2019063404 hasConceptScore W2019063404C188816634 @default.
• W2019063404 hasConceptScore W2019063404C2775892965 @default.
• W2019063404 hasConceptScore W2019063404C2908647359 @default.
• W2019063404 hasConceptScore W2019063404C71924100 @default.
• W2019063404 hasConceptScore W2019063404C99454951 @default.
• W2019063404 hasIssue "8" @default.
• W2019063404 hasLocation W20190634041 @default.
• W2019063404 hasLocation W20190634042 @default.
• W2019063404 hasOpenAccess W2019063404 @default.
• W2019063404 hasPrimaryLocation W20190634041 @default.
• W2019063404 hasRelatedWork W1586374228 @default.
• W2019063404 hasRelatedWork W2003938723 @default.
• W2019063404 hasRelatedWork W2045240138 @default.
• W2019063404 hasRelatedWork W2047967234 @default.
• W2019063404 hasRelatedWork W2118496982 @default.
• W2019063404 hasRelatedWork W2364998975 @default.
• W2019063404 hasRelatedWork W2369162477 @default.
• W2019063404 hasRelatedWork W2439875401 @default.
• W2019063404 hasRelatedWork W4238867864 @default.
• W2019063404 hasRelatedWork W2525756941 @default.
• W2019063404 hasVolume "62" @default.
• W2019063404 isParatext "false" @default.
• W2019063404 isRetracted "false" @default.
• W2019063404 magId "2019063404" @default.
• W2019063404 workType "article" @default.