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- W2019075459 abstract "The recent publication that some bacteria could use arsenic instead of phosphorus for building their DNA triggered a large controversy in the astro/exobiology community. Most comments claim that such a substitution is not possible. Here, we address the same question of the presence of As in DNA from a pure theoretical point of view, beyond any biological consideration. By means of “First principle“ quantum calculations we found that there is no energetical or structural argument to reject the As to P substitution in the DNA helix. However, a topological analysis of the electron density shows that As-DNA is much more fragile and most probably will not survive because it lacks the covalent bonds that insure the stability of biological P-DNA." @default.
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- W2019075459 date "2014-01-01" @default.
- W2019075459 modified "2023-09-25" @default.
- W2019075459 title "About the presence of arsenic in prebiotic species" @default.
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- W2019075459 doi "https://doi.org/10.1051/bioconf/20140204003" @default.
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