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- W2019094880 abstract "Total external ophthalmoplegia, unresponsive to caloric stimulation, was observed in a gravid woman who had ingested approximately 1.0 to 1.5 gm of amitriptyline. The intravenous administration of 4.0 mg physostigmine salicylate (PS) produced a revival of consciousness and reflex activity but had no appreciable effect on ocular motility. A prior case report of amitriptyline-induced ophthalmoplegia in a patient who took lesser amounts of the medication described immediate restoration of eye movement with only 2 mg of intravenous PS. The action of the amitriptyline on the vestibuloocular reflex seems to involve cholinergic transmission and the effect of the drug may be dose related." @default.
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- W2019094880 date "1981-09-01" @default.
- W2019094880 modified "2023-10-02" @default.
- W2019094880 title "Amitriptyline-induced ophthalmoplegia" @default.
- W2019094880 doi "https://doi.org/10.1212/wnl.31.9.1188" @default.
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