FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019096449> ?p ?o ?g. }

• W2019096449 abstract "Nanoparticles (NPs), materials that have one dimension less than 100 nm, are used in manufacturing, health, and food products, and consumer products including cosmetics, clothing, and household appliances. Their utility to industry is derived from their high surface-area-to-volume ratios and physico-chemical properties distinct from their bulk counterparts, but the near-certainty that NPs will be released into the environment raises the possibility that they could present health risks to humans and wildlife. The thyroid hormones (THs), thyroxine, and 3,3',5-triiodothyronine (T3), are involved in development and metabolism in vertebrates including humans and frogs. Many of the processes of anuran metamorphosis are analogous to human post-embryonic development and disruption of TH action can have drastic effects. These shared features make the metamorphosis of anurans an excellent model for screening for endocrine disrupting chemicals (EDCs). We used the cultured tailfin (C-fin) assay to examine the exposure effects of 0.1-10 nM (~8-800 ng/L) of three types of ~20 nm TiO2 NPs (P25, M212, M262) and micron-sized TiO2 (μ TiO2) ±10 nM T3. The actual Ti levels were 40.9-64.7% of the nominal value. Real-time quantitative polymerase chain reaction (QPCR) was used to measure the relative amounts of mRNA transcripts encoding TH-responsive THs receptors (thra and thrb) and Rana larval keratin type I (rlk1), as well as the cellular stress-responsive heat shock protein 30 kDa (hsp30), superoxide dismutase (sod), and catalase (cat). The levels of the TH-responsive transcripts were largely unaffected by any form of TiO2. Some significant effects on stress-related transcripts were observed upon exposure to micron-sized TiO2, P25, and M212 while no effect was observed with M262 exposure. Therefore, the risk of adversely affecting amphibian tissue by disrupting TH-signaling or inducing cellular stress is low for these compounds relative to other previously-tested NPs." @default.
• W2019096449 created "2016-06-24" @default.
• W2019096449 creator A5002047750 @default.
• W2019096449 creator A5061832689 @default.
• W2019096449 creator A5082440634 @default.
• W2019096449 date "2013-01-01" @default.
• W2019096449 modified "2023-09-26" @default.
• W2019096449 title "Evaluation of the effects of titanium dioxide nanoparticles on cultured Rana catesbeiana tailfin tissue" @default.
• W2019096449 cites W1546602409 @default.
• W2019096449 cites W1559461791 @default.
• W2019096449 cites W1964725018 @default.
• W2019096449 cites W1966653689 @default.
• W2019096449 cites W1967487924 @default.
• W2019096449 cites W1969132376 @default.
• W2019096449 cites W1970411171 @default.
• W2019096449 cites W1975825403 @default.
• W2019096449 cites W1975979895 @default.
• W2019096449 cites W1983182021 @default.
• W2019096449 cites W1991236309 @default.
• W2019096449 cites W1992569247 @default.
• W2019096449 cites W1995173605 @default.
• W2019096449 cites W2004720371 @default.
• W2019096449 cites W2004771577 @default.
• W2019096449 cites W2011077907 @default.
• W2019096449 cites W2012165420 @default.
• W2019096449 cites W2012319331 @default.
• W2019096449 cites W2017899735 @default.
• W2019096449 cites W2023704290 @default.
• W2019096449 cites W2025517512 @default.
• W2019096449 cites W2030442266 @default.
• W2019096449 cites W2034975045 @default.
• W2019096449 cites W2039108854 @default.
• W2019096449 cites W2050081396 @default.
• W2019096449 cites W2052410593 @default.
• W2019096449 cites W2053471764 @default.
• W2019096449 cites W2055403542 @default.
• W2019096449 cites W2067058980 @default.
• W2019096449 cites W2067561359 @default.
• W2019096449 cites W2069195858 @default.
• W2019096449 cites W2074013606 @default.
• W2019096449 cites W2077828942 @default.
• W2019096449 cites W2083446334 @default.
• W2019096449 cites W2087366241 @default.
• W2019096449 cites W2096761616 @default.
• W2019096449 cites W2099191918 @default.
• W2019096449 cites W2107277218 @default.
• W2019096449 cites W2115533910 @default.
• W2019096449 cites W2115940794 @default.
• W2019096449 cites W2120106657 @default.
• W2019096449 cites W2121425724 @default.
• W2019096449 cites W2151805900 @default.
• W2019096449 cites W2153909802 @default.
• W2019096449 cites W2269531128 @default.
• W2019096449 cites W2308426276 @default.
• W2019096449 cites W2067078286 @default.
• W2019096449 doi "https://doi.org/10.3389/fgene.2013.00251" @default.
• W2019096449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3836013" @default.
• W2019096449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24312126" @default.
• W2019096449 hasPublicationYear "2013" @default.
• W2019096449 type Work @default.
• W2019096449 sameAs 2019096449 @default.
• W2019096449 citedByCount "18" @default.
• W2019096449 countsByYear W20190964492015 @default.
• W2019096449 countsByYear W20190964492016 @default.
• W2019096449 countsByYear W20190964492018 @default.
• W2019096449 countsByYear W20190964492019 @default.
• W2019096449 countsByYear W20190964492020 @default.
• W2019096449 countsByYear W20190964492022 @default.
• W2019096449 countsByYear W20190964492023 @default.
• W2019096449 crossrefType "journal-article" @default.
• W2019096449 hasAuthorship W2019096449A5002047750 @default.
• W2019096449 hasAuthorship W2019096449A5061832689 @default.
• W2019096449 hasAuthorship W2019096449A5082440634 @default.
• W2019096449 hasBestOaLocation W20190964491 @default.
• W2019096449 hasConcept C12554922 @default.
• W2019096449 hasConcept C126322002 @default.
• W2019096449 hasConcept C134018914 @default.
• W2019096449 hasConcept C136397037 @default.
• W2019096449 hasConcept C173758957 @default.
• W2019096449 hasConcept C185592680 @default.
• W2019096449 hasConcept C18903297 @default.
• W2019096449 hasConcept C2775838275 @default.
• W2019096449 hasConcept C2776151105 @default.
• W2019096449 hasConcept C2778288131 @default.
• W2019096449 hasConcept C2778979269 @default.
• W2019096449 hasConcept C33070731 @default.
• W2019096449 hasConcept C71315377 @default.
• W2019096449 hasConcept C71572567 @default.
• W2019096449 hasConcept C71924100 @default.
• W2019096449 hasConcept C86803240 @default.
• W2019096449 hasConcept C95444343 @default.
• W2019096449 hasConceptScore W2019096449C12554922 @default.
• W2019096449 hasConceptScore W2019096449C126322002 @default.
• W2019096449 hasConceptScore W2019096449C134018914 @default.
• W2019096449 hasConceptScore W2019096449C136397037 @default.
• W2019096449 hasConceptScore W2019096449C173758957 @default.
• W2019096449 hasConceptScore W2019096449C185592680 @default.
• W2019096449 hasConceptScore W2019096449C18903297 @default.
• W2019096449 hasConceptScore W2019096449C2775838275 @default.
• W2019096449 hasConceptScore W2019096449C2776151105 @default.

• next