Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019132845> ?p ?o ?g. }
- W2019132845 endingPage "556" @default.
- W2019132845 startingPage "551" @default.
- W2019132845 abstract "The S-100 Ca2+ binding protein, calprotectin, isolated from neutrophil lysates, has been reported to exhibit zinc reversible biostatic activity in vitro. We verified these findings with C. albicans and investigated whether the growth inhibition resulted from zinc deprivation due to chelation by calprotectin. Calprotectin concentrations of 250 micrograms/ml significantly inhibited the growth of C. albicans. This was reversed by supplementing culture medium with 10 microM ZnSO4. Incubation of calprotectin in culture medium for 24 h prior to inoculation significantly reduced the minimum inhibitory concentration. When this latter medium was ultrafiltered to remove the calprotectin and then inoculated with C. albicans, significant growth inhibition was still present: again it was reversed by zinc. These findings implicate zinc chelation as a novel, potentially important host defence function of an abundant neutrophil protein." @default.
- W2019132845 created "2016-06-24" @default.
- W2019132845 creator A5065064899 @default.
- W2019132845 creator A5071909587 @default.
- W2019132845 date "1995-11-01" @default.
- W2019132845 modified "2023-09-27" @default.
- W2019132845 title "Calprotectin-Mediated Zinc Chelation as a Biostatic Mechanism in Host Defence" @default.
- W2019132845 cites W1660611080 @default.
- W2019132845 cites W1756522554 @default.
- W2019132845 cites W1925392529 @default.
- W2019132845 cites W1977665128 @default.
- W2019132845 cites W1982650409 @default.
- W2019132845 cites W1993416081 @default.
- W2019132845 cites W1995353543 @default.
- W2019132845 cites W1997236045 @default.
- W2019132845 cites W2007286072 @default.
- W2019132845 cites W2016541839 @default.
- W2019132845 cites W2021873282 @default.
- W2019132845 cites W2043970797 @default.
- W2019132845 cites W2060866852 @default.
- W2019132845 cites W2098053923 @default.
- W2019132845 cites W2133955925 @default.
- W2019132845 cites W2135864712 @default.
- W2019132845 cites W2136447195 @default.
- W2019132845 cites W2331260715 @default.
- W2019132845 cites W4233880858 @default.
- W2019132845 doi "https://doi.org/10.1111/j.1365-3083.1995.tb03695.x" @default.
- W2019132845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7481561" @default.
- W2019132845 hasPublicationYear "1995" @default.
- W2019132845 type Work @default.
- W2019132845 sameAs 2019132845 @default.
- W2019132845 citedByCount "187" @default.
- W2019132845 countsByYear W20191328452012 @default.
- W2019132845 countsByYear W20191328452013 @default.
- W2019132845 countsByYear W20191328452014 @default.
- W2019132845 countsByYear W20191328452015 @default.
- W2019132845 countsByYear W20191328452016 @default.
- W2019132845 countsByYear W20191328452017 @default.
- W2019132845 countsByYear W20191328452018 @default.
- W2019132845 countsByYear W20191328452019 @default.
- W2019132845 countsByYear W20191328452020 @default.
- W2019132845 countsByYear W20191328452021 @default.
- W2019132845 countsByYear W20191328452022 @default.
- W2019132845 countsByYear W20191328452023 @default.
- W2019132845 crossrefType "journal-article" @default.
- W2019132845 hasAuthorship W2019132845A5065064899 @default.
- W2019132845 hasAuthorship W2019132845A5071909587 @default.
- W2019132845 hasConcept C126322002 @default.
- W2019132845 hasConcept C145081991 @default.
- W2019132845 hasConcept C178790620 @default.
- W2019132845 hasConcept C185592680 @default.
- W2019132845 hasConcept C197404232 @default.
- W2019132845 hasConcept C202751555 @default.
- W2019132845 hasConcept C25642318 @default.
- W2019132845 hasConcept C2778260677 @default.
- W2019132845 hasConcept C2778292693 @default.
- W2019132845 hasConcept C2779134260 @default.
- W2019132845 hasConcept C2779707156 @default.
- W2019132845 hasConcept C2780917455 @default.
- W2019132845 hasConcept C535196362 @default.
- W2019132845 hasConcept C55493867 @default.
- W2019132845 hasConcept C71924100 @default.
- W2019132845 hasConcept C86803240 @default.
- W2019132845 hasConcept C89423630 @default.
- W2019132845 hasConceptScore W2019132845C126322002 @default.
- W2019132845 hasConceptScore W2019132845C145081991 @default.
- W2019132845 hasConceptScore W2019132845C178790620 @default.
- W2019132845 hasConceptScore W2019132845C185592680 @default.
- W2019132845 hasConceptScore W2019132845C197404232 @default.
- W2019132845 hasConceptScore W2019132845C202751555 @default.
- W2019132845 hasConceptScore W2019132845C25642318 @default.
- W2019132845 hasConceptScore W2019132845C2778260677 @default.
- W2019132845 hasConceptScore W2019132845C2778292693 @default.
- W2019132845 hasConceptScore W2019132845C2779134260 @default.
- W2019132845 hasConceptScore W2019132845C2779707156 @default.
- W2019132845 hasConceptScore W2019132845C2780917455 @default.
- W2019132845 hasConceptScore W2019132845C535196362 @default.
- W2019132845 hasConceptScore W2019132845C55493867 @default.
- W2019132845 hasConceptScore W2019132845C71924100 @default.
- W2019132845 hasConceptScore W2019132845C86803240 @default.
- W2019132845 hasConceptScore W2019132845C89423630 @default.
- W2019132845 hasIssue "5" @default.
- W2019132845 hasLocation W20191328451 @default.
- W2019132845 hasLocation W20191328452 @default.
- W2019132845 hasOpenAccess W2019132845 @default.
- W2019132845 hasPrimaryLocation W20191328451 @default.
- W2019132845 hasRelatedWork W2081512173 @default.
- W2019132845 hasRelatedWork W2128291007 @default.
- W2019132845 hasRelatedWork W2298392156 @default.
- W2019132845 hasRelatedWork W2888350538 @default.
- W2019132845 hasRelatedWork W2941029072 @default.
- W2019132845 hasRelatedWork W2946449973 @default.
- W2019132845 hasRelatedWork W3092085651 @default.
- W2019132845 hasRelatedWork W3104380876 @default.
- W2019132845 hasRelatedWork W4297252087 @default.
- W2019132845 hasRelatedWork W4300690271 @default.
- W2019132845 hasVolume "42" @default.
- W2019132845 isParatext "false" @default.