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- W2019136998 abstract "To the Editor: We wish to thank Dr. Froehner for his valuable comments. His statement that the rates of lung cancer are more elevated among brachytherapy candidates than among surgical candidates is very pertinent. It is also very pertinent to suggest that controlling for age and comorbidities may indirectly eliminate some of the differences that might exist between radiotherapy patients and their radical prostatectomy counterparts. However, as his observation about brachytherapy and surgery cohorts suggests, these differences might not be eliminated completely. This reasoning suggests that important differences may exist between radiotherapy and radical prostatectomy patients with regard to lung cancer risk. Effective elimination of such differences indeed would require a randomized trial. Since the present study did not rely on a randomized design, we do echo the cautionary words of Dr. Froehner about using caution in the interpretation of the numbers needed to harm. Response to “The Rate of Secondary Malignancies After Radical Prostatectomy Versus External Beam Radiation Therapy for Localized Prostate Cancer: A Population-Based Study on 17,845 Patients.” (Int J Radiat Oncol Biol Phys 2010;76:342–348)International Journal of Radiation Oncology, Biology, PhysicsVol. 78Issue 4PreviewTo the Editor: We read with great interest the study by Bhojani and coworkers demonstrating an increased incidence of secondary malignancies in patients who received external beam radiotherapy compared with those who underwent radical prostatectomy. The difference was particularly pronounced concerning lung cancer (1). Earlier studies yielded similar results (2, 3). Full-Text PDF" @default.
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- W2019136998 date "2010-11-01" @default.
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- W2019136998 title "In Reply to Drs. Froehner and Wirth" @default.
- W2019136998 doi "https://doi.org/10.1016/j.ijrobp.2010.03.052" @default.
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