Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019148515> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2019148515 endingPage "302" @default.
- W2019148515 startingPage "302" @default.
- W2019148515 abstract "Background: HIV–TB (tuberculosis) coinfection has emerged as a major public health threat. Given the multifactorial enabling environment in a resource-constrained setting like India, the consequences are of epidemic proportions. Aims: This study was aimed at identifying the clinical and epidemiological determinants underlying HIV–TB coinfection. Settings and Design: A retrospective review of patient records was done from the antiretroviral therapy center (ART) center at a district hospital in southern India between May and August 2012. Materials and Methods: Secondary data of 684 patients on ART as well as pre-ART were collected between July 2008 and June 2012 and were analyzed. Statistical Analysis: Descriptive analysis, χ2, and Wilcoxon signed rank tests were used with SPSS version 15.0 to draw significant statistical inferences. Results: HIV–TB coinfection was diagnosed in 18.9% with higher prevalence among males (75.3%), in the sexually active age group 31-45 years (61.3%), with less than primary education (44.15%), who were married (56.1%), laborers (42.4%), from rural backgrounds (88.2%), and having low income-earning capacity (94.4%). Transmission was predominantly through the heterosexual route. The key entry point was the integrated counseling and testing center (ICTC) (47.4%). Pulmonary tuberculosis (58.8%) was predominantly found followed by extrapulmonary tuberculosis (38.2%) and both in 3.1%. A favorable outcome was observed in 69.3% of coinfected patients with 89.2% on ART and 97.2% currently on DOTS therapy. The Wilcoxon signed-rank test found significant association between rises in CD4 counts after the 6th-month follow up (P < 0.05). Coinfected patients had a case fatality rate of 25%. Conclusions: The prevalence of HIV–TB coinfection recorded in this sample was 18.86%. ICTC implemented by NACO emerged as an effective entry point, while Revised National Tuberculosis Control Program referred 1.6% (n = 11) of the patients to the ART center. Coinfection is associated with lower CD4 counts than those with HIV alone, which could translate into increased morbidity and progression of HIV to AIDS." @default.
- W2019148515 created "2016-06-24" @default.
- W2019148515 creator A5006340816 @default.
- W2019148515 creator A5018994139 @default.
- W2019148515 creator A5029273299 @default.
- W2019148515 creator A5055313590 @default.
- W2019148515 creator A5086474562 @default.
- W2019148515 date "2013-01-01" @default.
- W2019148515 modified "2023-09-27" @default.
- W2019148515 title "HIV-TB coinfection: Clinico-epidemiological determinants at an antiretroviral therapy center in Southern India" @default.
- W2019148515 doi "https://doi.org/10.4103/0970-2113.120605" @default.
- W2019148515 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3841686" @default.
- W2019148515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24339487" @default.
- W2019148515 hasPublicationYear "2013" @default.
- W2019148515 type Work @default.
- W2019148515 sameAs 2019148515 @default.
- W2019148515 citedByCount "19" @default.
- W2019148515 countsByYear W20191485152014 @default.
- W2019148515 countsByYear W20191485152015 @default.
- W2019148515 countsByYear W20191485152016 @default.
- W2019148515 countsByYear W20191485152017 @default.
- W2019148515 countsByYear W20191485152018 @default.
- W2019148515 countsByYear W20191485152020 @default.
- W2019148515 countsByYear W20191485152023 @default.
- W2019148515 crossrefType "journal-article" @default.
- W2019148515 hasAuthorship W2019148515A5006340816 @default.
- W2019148515 hasAuthorship W2019148515A5018994139 @default.
- W2019148515 hasAuthorship W2019148515A5029273299 @default.
- W2019148515 hasAuthorship W2019148515A5055313590 @default.
- W2019148515 hasAuthorship W2019148515A5086474562 @default.
- W2019148515 hasBestOaLocation W20191485151 @default.
- W2019148515 hasConcept C107130276 @default.
- W2019148515 hasConcept C126322002 @default.
- W2019148515 hasConcept C142724271 @default.
- W2019148515 hasConcept C144024400 @default.
- W2019148515 hasConcept C149923435 @default.
- W2019148515 hasConcept C167135981 @default.
- W2019148515 hasConcept C187212893 @default.
- W2019148515 hasConcept C2777813720 @default.
- W2019148515 hasConcept C2781069245 @default.
- W2019148515 hasConcept C3013748606 @default.
- W2019148515 hasConcept C512399662 @default.
- W2019148515 hasConcept C71924100 @default.
- W2019148515 hasConceptScore W2019148515C107130276 @default.
- W2019148515 hasConceptScore W2019148515C126322002 @default.
- W2019148515 hasConceptScore W2019148515C142724271 @default.
- W2019148515 hasConceptScore W2019148515C144024400 @default.
- W2019148515 hasConceptScore W2019148515C149923435 @default.
- W2019148515 hasConceptScore W2019148515C167135981 @default.
- W2019148515 hasConceptScore W2019148515C187212893 @default.
- W2019148515 hasConceptScore W2019148515C2777813720 @default.
- W2019148515 hasConceptScore W2019148515C2781069245 @default.
- W2019148515 hasConceptScore W2019148515C3013748606 @default.
- W2019148515 hasConceptScore W2019148515C512399662 @default.
- W2019148515 hasConceptScore W2019148515C71924100 @default.
- W2019148515 hasIssue "4" @default.
- W2019148515 hasLocation W20191485151 @default.
- W2019148515 hasLocation W20191485152 @default.
- W2019148515 hasLocation W20191485153 @default.
- W2019148515 hasLocation W20191485154 @default.
- W2019148515 hasLocation W20191485155 @default.
- W2019148515 hasOpenAccess W2019148515 @default.
- W2019148515 hasPrimaryLocation W20191485151 @default.
- W2019148515 hasRelatedWork W129324069 @default.
- W2019148515 hasRelatedWork W1665834207 @default.
- W2019148515 hasRelatedWork W2609175419 @default.
- W2019148515 hasRelatedWork W2752012394 @default.
- W2019148515 hasRelatedWork W3133544574 @default.
- W2019148515 hasRelatedWork W3185964715 @default.
- W2019148515 hasRelatedWork W3215569114 @default.
- W2019148515 hasRelatedWork W4226457200 @default.
- W2019148515 hasRelatedWork W4323968667 @default.
- W2019148515 hasRelatedWork W3142144551 @default.
- W2019148515 hasVolume "30" @default.
- W2019148515 isParatext "false" @default.
- W2019148515 isRetracted "false" @default.
- W2019148515 magId "2019148515" @default.
- W2019148515 workType "article" @default.