Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019161946> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2019161946 abstract "Serum-free cultures of human peripheral blood mononuclear cells from normal volunteers produce an inhibitor of neutrophil chemotaxis when exposed to heat-killed staphylococci. Human neutrophils were exposed to 100-fold dilutions of supernatants from 6-hr cultures, washed repeatedly, and assayed for chemotactic responsiveness with a radiolabel assay. Dilutions of supernatants from cell cultures exposed to staphylococci resulted in a mean chemotaxis of 856 +/- 83 cpm (n = 21), while that for medium-treated neutrophils was 1,354 +/- 100 cpm (n = 21, P less than .001), and supernatants from cultures without staphylococci produced chemotaxis of 1,107 +/- 132 cpm (n = 14, P greater than .05 vs. medium-treated). Fifty-three experiments on tissue from 26 donors showed that after 6 hr the mean inhibition (+/- SE) of chemotaxis at 1:100 dilution was 26.4% +/- 3.3% (P less than .001 vs. medium-treated). It was found that the peptidoglycan fraction of the staphylococci was sufficient to induce production of inhibitor by the cooperative action of T cells and monocytes. The inhibitor is a protein with a molecular mass of 30-45 kilodaltons. It is not toxic to the neutrophils and does not affect secretion, adhesion, phagocytosis, or the ability to kill Staphylococcus aureus. This potent inhibitor of neutrophil chemotaxis may play a role in the modulation of neutrophil function during bacterial infections." @default.
- W2019161946 created "2016-06-24" @default.
- W2019161946 creator A5091900939 @default.
- W2019161946 date "1985-07-01" @default.
- W2019161946 modified "2023-09-26" @default.
- W2019161946 title "Human Mononuclear Cells Exposed to Staphylococci Rapidly Produce an Inhibitor of Neutrophil Chemotaxis" @default.
- W2019161946 cites W11645413 @default.
- W2019161946 cites W1520385356 @default.
- W2019161946 cites W1566830427 @default.
- W2019161946 cites W1631426208 @default.
- W2019161946 cites W1655486177 @default.
- W2019161946 cites W1889110649 @default.
- W2019161946 cites W1909642617 @default.
- W2019161946 cites W1942168138 @default.
- W2019161946 cites W1981684603 @default.
- W2019161946 cites W1987251328 @default.
- W2019161946 cites W1988359235 @default.
- W2019161946 cites W1990792235 @default.
- W2019161946 cites W2002307260 @default.
- W2019161946 cites W2025133365 @default.
- W2019161946 cites W2033751913 @default.
- W2019161946 cites W2064496555 @default.
- W2019161946 cites W2086259503 @default.
- W2019161946 cites W2095903710 @default.
- W2019161946 cites W2151311876 @default.
- W2019161946 cites W2171697344 @default.
- W2019161946 cites W2221376210 @default.
- W2019161946 cites W634313850 @default.
- W2019161946 cites W87082738 @default.
- W2019161946 doi "https://doi.org/10.1093/infdis/152.1.24" @default.
- W2019161946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3874251" @default.
- W2019161946 hasPublicationYear "1985" @default.
- W2019161946 type Work @default.
- W2019161946 sameAs 2019161946 @default.
- W2019161946 citedByCount "12" @default.
- W2019161946 crossrefType "journal-article" @default.
- W2019161946 hasAuthorship W2019161946A5091900939 @default.
- W2019161946 hasConcept C137061746 @default.
- W2019161946 hasConcept C142724271 @default.
- W2019161946 hasConcept C153911025 @default.
- W2019161946 hasConcept C160448771 @default.
- W2019161946 hasConcept C170493617 @default.
- W2019161946 hasConcept C184112429 @default.
- W2019161946 hasConcept C198677920 @default.
- W2019161946 hasConcept C202751555 @default.
- W2019161946 hasConcept C203014093 @default.
- W2019161946 hasConcept C204787440 @default.
- W2019161946 hasConcept C2776634448 @default.
- W2019161946 hasConcept C2776914184 @default.
- W2019161946 hasConcept C2779489039 @default.
- W2019161946 hasConcept C2779866169 @default.
- W2019161946 hasConcept C2780656570 @default.
- W2019161946 hasConcept C523546767 @default.
- W2019161946 hasConcept C54166955 @default.
- W2019161946 hasConcept C54355233 @default.
- W2019161946 hasConcept C55493867 @default.
- W2019161946 hasConcept C71924100 @default.
- W2019161946 hasConcept C86803240 @default.
- W2019161946 hasConcept C89423630 @default.
- W2019161946 hasConceptScore W2019161946C137061746 @default.
- W2019161946 hasConceptScore W2019161946C142724271 @default.
- W2019161946 hasConceptScore W2019161946C153911025 @default.
- W2019161946 hasConceptScore W2019161946C160448771 @default.
- W2019161946 hasConceptScore W2019161946C170493617 @default.
- W2019161946 hasConceptScore W2019161946C184112429 @default.
- W2019161946 hasConceptScore W2019161946C198677920 @default.
- W2019161946 hasConceptScore W2019161946C202751555 @default.
- W2019161946 hasConceptScore W2019161946C203014093 @default.
- W2019161946 hasConceptScore W2019161946C204787440 @default.
- W2019161946 hasConceptScore W2019161946C2776634448 @default.
- W2019161946 hasConceptScore W2019161946C2776914184 @default.
- W2019161946 hasConceptScore W2019161946C2779489039 @default.
- W2019161946 hasConceptScore W2019161946C2779866169 @default.
- W2019161946 hasConceptScore W2019161946C2780656570 @default.
- W2019161946 hasConceptScore W2019161946C523546767 @default.
- W2019161946 hasConceptScore W2019161946C54166955 @default.
- W2019161946 hasConceptScore W2019161946C54355233 @default.
- W2019161946 hasConceptScore W2019161946C55493867 @default.
- W2019161946 hasConceptScore W2019161946C71924100 @default.
- W2019161946 hasConceptScore W2019161946C86803240 @default.
- W2019161946 hasConceptScore W2019161946C89423630 @default.
- W2019161946 hasLocation W20191619461 @default.
- W2019161946 hasLocation W20191619462 @default.
- W2019161946 hasOpenAccess W2019161946 @default.
- W2019161946 hasPrimaryLocation W20191619461 @default.
- W2019161946 hasRelatedWork W1857561247 @default.
- W2019161946 hasRelatedWork W1968402220 @default.
- W2019161946 hasRelatedWork W1978484768 @default.
- W2019161946 hasRelatedWork W2019161946 @default.
- W2019161946 hasRelatedWork W2028084628 @default.
- W2019161946 hasRelatedWork W2050876779 @default.
- W2019161946 hasRelatedWork W2132841322 @default.
- W2019161946 hasRelatedWork W2324196088 @default.
- W2019161946 hasRelatedWork W2410207023 @default.
- W2019161946 hasRelatedWork W2426598329 @default.
- W2019161946 isParatext "false" @default.
- W2019161946 isRetracted "false" @default.
- W2019161946 magId "2019161946" @default.
- W2019161946 workType "article" @default.