FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019173364> ?p ?o ?g. }

• W2019173364 endingPage "e89" @default.
• W2019173364 startingPage "e89" @default.
• W2019173364 abstract "Background: Osteosarcoma is the most common primary bone sarcoma and affects all ages. There are substantial differences in management and outcomes for patients who have localized disease compared with distant spread at the time of diagnosis. Our goal was to examine potential risk factors predictive of metastatic disease at presentation. Methods: The Surveillance, Epidemiology, and End Results (SEER) Program database was used to identify all patients diagnosed with osteosarcoma from 2000 to 2008 and to classify each patient as having metastatic or localized disease at the time of diagnosis. Patient-based characteristics, tumor characteristics, and county-level socioeconomic measures were analyzed to determine which factors were predictive of an increased rate of distant metastatic disease at presentation. These factors were analyzed as univariate characteristics as well as in a multivariate logistic regression model. Results: We identified 2017 cases of high-grade osteosarcoma, and 464 (23.0%) of the patients presented with metastatic disease. In the unadjusted logistic regression analysis, patients had increased odds of metastatic disease at presentation if they had an age of sixty years or more (odds ratio [OR] = 2.22; 95% confidence interval [CI], 1.71 to 2.89), had a tumor located in the axial skeleton (OR = 2.47; 95% CI, 1.88 to 3.26), and lived in a county with low socioeconomic status (OR = 1.59; 95% CI, 1.08 to 2.35). These factors remained significant when combined in multivariate models controlling for age, location, and socioeconomic status. For patients with recorded tumor size information (n = 1398), the odds of metastasis at presentation increased by 10% with each additional centimeter of tumor size (OR = 1.10; 95% CI, 1.08 to 1.13). When the patients with missing tumor size information were excluded, socioeconomic status was no longer a significant risk factor for metastasis at presentation in the multivariate model. Conclusions: Osteosarcoma patients with advanced age, a tumor in the axial skeleton, a larger tumor size, and a residence in a less affluent county were more likely to have metastatic disease at presentation. Level of Evidence: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence." @default.
• W2019173364 created "2016-06-24" @default.
• W2019173364 creator A5029895291 @default.
• W2019173364 creator A5071026390 @default.
• W2019173364 creator A5081108863 @default.
• W2019173364 creator A5089115266 @default.
• W2019173364 date "2013-07-03" @default.
• W2019173364 modified "2023-10-11" @default.
• W2019173364 title "Risk Factors for Metastatic Disease at Presentation with Osteosarcoma" @default.
• W2019173364 cites W1488327187 @default.
• W2019173364 cites W1495140191 @default.
• W2019173364 cites W1566439958 @default.
• W2019173364 cites W1590471737 @default.
• W2019173364 cites W1988325237 @default.
• W2019173364 cites W2014055476 @default.
• W2019173364 cites W2018441425 @default.
• W2019173364 cites W2027887604 @default.
• W2019173364 cites W2046548272 @default.
• W2019173364 cites W2052299135 @default.
• W2019173364 cites W2076712225 @default.
• W2019173364 cites W2084572811 @default.
• W2019173364 cites W2087503191 @default.
• W2019173364 cites W2117090889 @default.
• W2019173364 cites W2121769039 @default.
• W2019173364 cites W2127748864 @default.
• W2019173364 cites W2130383002 @default.
• W2019173364 cites W2140700546 @default.
• W2019173364 cites W2145102222 @default.
• W2019173364 cites W2153198267 @default.
• W2019173364 cites W2169988533 @default.
• W2019173364 cites W2277536847 @default.
• W2019173364 cites W2410586658 @default.
• W2019173364 cites W4246742253 @default.
• W2019173364 doi "https://doi.org/10.2106/jbjs.l.01189" @default.
• W2019173364 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3689260" @default.
• W2019173364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23824394" @default.
• W2019173364 hasPublicationYear "2013" @default.
• W2019173364 type Work @default.
• W2019173364 sameAs 2019173364 @default.
• W2019173364 citedByCount "138" @default.
• W2019173364 countsByYear W20191733642013 @default.
• W2019173364 countsByYear W20191733642014 @default.
• W2019173364 countsByYear W20191733642015 @default.
• W2019173364 countsByYear W20191733642016 @default.
• W2019173364 countsByYear W20191733642017 @default.
• W2019173364 countsByYear W20191733642018 @default.
• W2019173364 countsByYear W20191733642019 @default.
• W2019173364 countsByYear W20191733642020 @default.
• W2019173364 countsByYear W20191733642021 @default.
• W2019173364 countsByYear W20191733642022 @default.
• W2019173364 countsByYear W20191733642023 @default.
• W2019173364 crossrefType "journal-article" @default.
• W2019173364 hasAuthorship W2019173364A5029895291 @default.
• W2019173364 hasAuthorship W2019173364A5071026390 @default.
• W2019173364 hasAuthorship W2019173364A5081108863 @default.
• W2019173364 hasAuthorship W2019173364A5089115266 @default.
• W2019173364 hasBestOaLocation W20191733642 @default.
• W2019173364 hasConcept C107130276 @default.
• W2019173364 hasConcept C126322002 @default.
• W2019173364 hasConcept C142724271 @default.
• W2019173364 hasConcept C143095724 @default.
• W2019173364 hasConcept C143998085 @default.
• W2019173364 hasConcept C144301174 @default.
• W2019173364 hasConcept C147077947 @default.
• W2019173364 hasConcept C151956035 @default.
• W2019173364 hasConcept C156957248 @default.
• W2019173364 hasConcept C2777760704 @default.
• W2019173364 hasConcept C2778527826 @default.
• W2019173364 hasConcept C2779134260 @default.
• W2019173364 hasConcept C2779391198 @default.
• W2019173364 hasConcept C2908647359 @default.
• W2019173364 hasConcept C38180746 @default.
• W2019173364 hasConcept C44249647 @default.
• W2019173364 hasConcept C71924100 @default.
• W2019173364 hasConcept C99454951 @default.
• W2019173364 hasConceptScore W2019173364C107130276 @default.
• W2019173364 hasConceptScore W2019173364C126322002 @default.
• W2019173364 hasConceptScore W2019173364C142724271 @default.
• W2019173364 hasConceptScore W2019173364C143095724 @default.
• W2019173364 hasConceptScore W2019173364C143998085 @default.
• W2019173364 hasConceptScore W2019173364C144301174 @default.
• W2019173364 hasConceptScore W2019173364C147077947 @default.
• W2019173364 hasConceptScore W2019173364C151956035 @default.
• W2019173364 hasConceptScore W2019173364C156957248 @default.
• W2019173364 hasConceptScore W2019173364C2777760704 @default.
• W2019173364 hasConceptScore W2019173364C2778527826 @default.
• W2019173364 hasConceptScore W2019173364C2779134260 @default.
• W2019173364 hasConceptScore W2019173364C2779391198 @default.
• W2019173364 hasConceptScore W2019173364C2908647359 @default.
• W2019173364 hasConceptScore W2019173364C38180746 @default.
• W2019173364 hasConceptScore W2019173364C44249647 @default.
• W2019173364 hasConceptScore W2019173364C71924100 @default.
• W2019173364 hasConceptScore W2019173364C99454951 @default.
• W2019173364 hasIssue "13" @default.
• W2019173364 hasLocation W20191733641 @default.
• W2019173364 hasLocation W20191733642 @default.
• W2019173364 hasLocation W20191733643 @default.
• W2019173364 hasLocation W20191733644 @default.

• next