FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019183277> ?p ?o ?g. }

• W2019183277 endingPage "89" @default.
• W2019183277 startingPage "80" @default.
• W2019183277 abstract "Using immunofluorescence, RT-PCR, and Western blotting, we have demonstrated the ability of human B cells to express CD4. In each of the 10 lymphoblastoid cell lines (LCL) tested there was variable, but definite, proportion of CD4-positive B cells. Expression of CD4 was related to the cell cycle; CD4 was expressed in the G1 phase and continued at later phases of the cell cycle. CD4 was in part internalized and degraded by the LCL B cells. Surface CD4 was associated tolckand its crosslinking resulted in tyrosine phosphorylation. Additional experiments conducted on freshly prepared tonsillar B cells demonstrated that CD4 was expressed by large activated B cells, but not by small resting B cells. However, not all the activated tonsillar B cells had surface CD4 since germinal center cells were CD4-negative. Crosslinking of CD4 on LCL or on tonsillar activated B cells resulted in apoptosisin vitro,a finding that indicates the capacity of CD4 to deliver functional signals to B cells and to play a regulatory function in their physiology. Exposure of CD4 expressing B cells to gp120 under conditions that resulted in CD4 crosslinking also caused apoptosis suggesting some implications for the pathophysiology of AIDS." @default.
• W2019183277 created "2016-06-24" @default.
• W2019183277 creator A5003334973 @default.
• W2019183277 creator A5011115538 @default.
• W2019183277 creator A5015775506 @default.
• W2019183277 creator A5023709678 @default.
• W2019183277 creator A5028725821 @default.
• W2019183277 creator A5029620224 @default.
• W2019183277 creator A5030130957 @default.
• W2019183277 creator A5041663990 @default.
• W2019183277 creator A5083847518 @default.
• W2019183277 date "1999-04-01" @default.
• W2019183277 modified "2023-09-29" @default.
• W2019183277 title "Apoptosis Induced by Crosslinking of CD4 on Activated Human B Cells" @default.
• W2019183277 cites W138492706 @default.
• W2019183277 cites W1497645790 @default.
• W2019183277 cites W150403848 @default.
• W2019183277 cites W1524108517 @default.
• W2019183277 cites W1535536432 @default.
• W2019183277 cites W1591113877 @default.
• W2019183277 cites W173914716 @default.
• W2019183277 cites W1760815755 @default.
• W2019183277 cites W1964350991 @default.
• W2019183277 cites W1964892965 @default.
• W2019183277 cites W1971057735 @default.
• W2019183277 cites W1976739177 @default.
• W2019183277 cites W1996418577 @default.
• W2019183277 cites W1996934466 @default.
• W2019183277 cites W2002812563 @default.
• W2019183277 cites W2010748892 @default.
• W2019183277 cites W2013267240 @default.
• W2019183277 cites W2013796028 @default.
• W2019183277 cites W2017185316 @default.
• W2019183277 cites W2020055566 @default.
• W2019183277 cites W2021868882 @default.
• W2019183277 cites W2028055683 @default.
• W2019183277 cites W2028834214 @default.
• W2019183277 cites W2030039293 @default.
• W2019183277 cites W2036247818 @default.
• W2019183277 cites W2042875807 @default.
• W2019183277 cites W2044743484 @default.
• W2019183277 cites W2044907066 @default.
• W2019183277 cites W2046000758 @default.
• W2019183277 cites W2048889529 @default.
• W2019183277 cites W2049052619 @default.
• W2019183277 cites W2056723350 @default.
• W2019183277 cites W2065997152 @default.
• W2019183277 cites W2074416628 @default.
• W2019183277 cites W2076794779 @default.
• W2019183277 cites W2083556128 @default.
• W2019183277 cites W2086264258 @default.
• W2019183277 cites W2087163507 @default.
• W2019183277 cites W2091085026 @default.
• W2019183277 cites W2091392542 @default.
• W2019183277 cites W2091543887 @default.
• W2019183277 cites W2099247656 @default.
• W2019183277 cites W2106160458 @default.
• W2019183277 cites W2112044573 @default.
• W2019183277 cites W2116014786 @default.
• W2019183277 cites W2138651048 @default.
• W2019183277 cites W2139071356 @default.
• W2019183277 cites W2145596334 @default.
• W2019183277 cites W2147166534 @default.
• W2019183277 cites W2148370330 @default.
• W2019183277 cites W2148426299 @default.
• W2019183277 cites W2153919911 @default.
• W2019183277 cites W2159680966 @default.
• W2019183277 cites W2162543584 @default.
• W2019183277 cites W2167889445 @default.
• W2019183277 cites W2168857216 @default.
• W2019183277 cites W2288666255 @default.
• W2019183277 cites W2289682612 @default.
• W2019183277 cites W26089772 @default.
• W2019183277 cites W4240479615 @default.
• W2019183277 cites W4250859916 @default.
• W2019183277 doi "https://doi.org/10.1006/cimm.1999.1455" @default.
• W2019183277 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10202115" @default.
• W2019183277 hasPublicationYear "1999" @default.
• W2019183277 type Work @default.
• W2019183277 sameAs 2019183277 @default.
• W2019183277 citedByCount "10" @default.
• W2019183277 countsByYear W20191832772016 @default.
• W2019183277 countsByYear W20191832772021 @default.
• W2019183277 crossrefType "journal-article" @default.
• W2019183277 hasAuthorship W2019183277A5003334973 @default.
• W2019183277 hasAuthorship W2019183277A5011115538 @default.
• W2019183277 hasAuthorship W2019183277A5015775506 @default.
• W2019183277 hasAuthorship W2019183277A5023709678 @default.
• W2019183277 hasAuthorship W2019183277A5028725821 @default.
• W2019183277 hasAuthorship W2019183277A5029620224 @default.
• W2019183277 hasAuthorship W2019183277A5030130957 @default.
• W2019183277 hasAuthorship W2019183277A5041663990 @default.
• W2019183277 hasAuthorship W2019183277A5083847518 @default.
• W2019183277 hasConcept C104317684 @default.
• W2019183277 hasConcept C113842279 @default.
• W2019183277 hasConcept C153911025 @default.
• W2019183277 hasConcept C154317977 @default.
• W2019183277 hasConcept C159654299 @default.

• next