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- W2019196415 abstract "An appraisal of the current status of the thiouracil derivatives in the treatment of hyperthyroidism has been attempted, based upon an analysis of the records of fifty-six patients referred for surgery, all of whom had previously received some antithyroid treatment. The analysis brings to light examples of the misuse of these drugs. The most common faults include failure to control the hyperthyroidism completely, usually as the result of inadequate dosage; improper selection of cases for prolonged medical treatment, such as intrathoracic goiters, very large adenomatous goiters or large exophthalmic goiters; mistaken diagnosis—chiefly the use of prolonged antithyroid treatment in patients with anxiety neurosis; the use of dosages of drugs which are so small as to accomplish little beyond exposing the patient to the possibility of drug sensitivity. The preoperative use of thiouracil drugs is well established. A summary of the present status of prolonged use of thiouracil drugs as a form of medical treatment is presented." @default.
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- W2019196415 date "1951-01-01" @default.
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- W2019196415 title "Use and abuse of thiouracil drugs" @default.
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- W2019196415 doi "https://doi.org/10.1016/0002-9343(51)90220-3" @default.
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