FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019196893> ?p ?o ?g. }

• W2019196893 endingPage "74" @default.
• W2019196893 startingPage "68" @default.
• W2019196893 abstract "A new biosensor or protein label-free sensor composed of 1-butyl-3-methylimidazolium hexafluorophosphates (BMIMPF6)-human serum albumin (HSA) film on glassy carbon electrode (GCE) was produced. Unfortunately, the native proteins themselves are often unstable in physiological conditions. Here, we introduced conjugation with ionic liquid (IL) such as BMIMPF6 which improved the stability and binding affinity of protein onto GCE. A rapid, simple and reliable method for the chiral discrimination and real time protein binding studies of fenoprofen enantiomers with HSA was developed by hyphenating ionic liquid albumin glassy carbon (ILAGC) biosensor with differential pulse cathodic stripping voltammetry under physiological conditions. The electrochemical behavior of chiral fenoprofen was monitored by cyclic voltammetry, from which large response was obtained from l-fenoprofen. The surface coverage of fenoprofen enantiomers was calculated by double potential-step chronocoulometry. The binding constants of chiral fenoprofen with HSA were estimated to be 3.2 × 105 ± 0.3 L mol−1 and 0.8 × 104 ± 0.4 L mol−1 for l- and d-fenoprofen, respectively giving acceptable precision (SD ≤ 0.4) and good agreement with the literature values. The competitive interactions of ibuprofen with fenoprofen enantiomers–HSA were studied giving a significant decreasing in the binding degrees of analytes to HSA. The reciprocal competitive experiments indicated that l-fenoprofen replaced d-fenoprofen from HSA. The proposed electrochemical biosensor holds great potential for chiral discrimination and real time binding studies of drugs with protein." @default.
• W2019196893 created "2016-06-24" @default.
• W2019196893 creator A5010242865 @default.
• W2019196893 creator A5089219092 @default.
• W2019196893 date "2013-04-01" @default.
• W2019196893 modified "2023-10-16" @default.
• W2019196893 title "Hyphenation of ionic liquid albumin glassy carbon biosensor or protein label-free sensor with differential pulse stripping voltammetry for interaction studies of human serum albumin with fenoprofen enantiomers" @default.
• W2019196893 cites W1966994931 @default.
• W2019196893 cites W1990279333 @default.
• W2019196893 cites W1992768525 @default.
• W2019196893 cites W1997043139 @default.
• W2019196893 cites W2009659101 @default.
• W2019196893 cites W2010264929 @default.
• W2019196893 cites W2018688487 @default.
• W2019196893 cites W2020981060 @default.
• W2019196893 cites W2029140936 @default.
• W2019196893 cites W2035685455 @default.
• W2019196893 cites W2036219335 @default.
• W2019196893 cites W2052058811 @default.
• W2019196893 cites W2054136918 @default.
• W2019196893 cites W2057633383 @default.
• W2019196893 cites W2063474945 @default.
• W2019196893 cites W2074218253 @default.
• W2019196893 cites W2079207000 @default.
• W2019196893 cites W2082473448 @default.
• W2019196893 cites W2098019254 @default.
• W2019196893 cites W2114469059 @default.
• W2019196893 cites W2140466011 @default.
• W2019196893 cites W2143515298 @default.
• W2019196893 cites W2168138061 @default.
• W2019196893 cites W2461917753 @default.
• W2019196893 cites W2765743114 @default.
• W2019196893 cites W4254064218 @default.
• W2019196893 doi "https://doi.org/10.1016/j.aca.2013.02.018" @default.
• W2019196893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23540249" @default.
• W2019196893 hasPublicationYear "2013" @default.
• W2019196893 type Work @default.
• W2019196893 sameAs 2019196893 @default.
• W2019196893 citedByCount "20" @default.
• W2019196893 countsByYear W20191968932013 @default.
• W2019196893 countsByYear W20191968932014 @default.
• W2019196893 countsByYear W20191968932015 @default.
• W2019196893 countsByYear W20191968932016 @default.
• W2019196893 countsByYear W20191968932018 @default.
• W2019196893 countsByYear W20191968932019 @default.
• W2019196893 countsByYear W20191968932020 @default.
• W2019196893 countsByYear W20191968932022 @default.
• W2019196893 countsByYear W20191968932023 @default.
• W2019196893 crossrefType "journal-article" @default.
• W2019196893 hasAuthorship W2019196893A5010242865 @default.
• W2019196893 hasAuthorship W2019196893A5089219092 @default.
• W2019196893 hasConcept C107824862 @default.
• W2019196893 hasConcept C113196181 @default.
• W2019196893 hasConcept C147789679 @default.
• W2019196893 hasConcept C154881586 @default.
• W2019196893 hasConcept C160756335 @default.
• W2019196893 hasConcept C161790260 @default.
• W2019196893 hasConcept C165616093 @default.
• W2019196893 hasConcept C17525397 @default.
• W2019196893 hasConcept C178790620 @default.
• W2019196893 hasConcept C185592680 @default.
• W2019196893 hasConcept C2776422427 @default.
• W2019196893 hasConcept C2777869211 @default.
• W2019196893 hasConcept C2778597219 @default.
• W2019196893 hasConcept C2779525745 @default.
• W2019196893 hasConcept C2779603750 @default.
• W2019196893 hasConcept C32786932 @default.
• W2019196893 hasConcept C43617362 @default.
• W2019196893 hasConcept C486523 @default.
• W2019196893 hasConcept C52859227 @default.
• W2019196893 hasConcept C55493867 @default.
• W2019196893 hasConcept C71240020 @default.
• W2019196893 hasConceptScore W2019196893C107824862 @default.
• W2019196893 hasConceptScore W2019196893C113196181 @default.
• W2019196893 hasConceptScore W2019196893C147789679 @default.
• W2019196893 hasConceptScore W2019196893C154881586 @default.
• W2019196893 hasConceptScore W2019196893C160756335 @default.
• W2019196893 hasConceptScore W2019196893C161790260 @default.
• W2019196893 hasConceptScore W2019196893C165616093 @default.
• W2019196893 hasConceptScore W2019196893C17525397 @default.
• W2019196893 hasConceptScore W2019196893C178790620 @default.
• W2019196893 hasConceptScore W2019196893C185592680 @default.
• W2019196893 hasConceptScore W2019196893C2776422427 @default.
• W2019196893 hasConceptScore W2019196893C2777869211 @default.
• W2019196893 hasConceptScore W2019196893C2778597219 @default.
• W2019196893 hasConceptScore W2019196893C2779525745 @default.
• W2019196893 hasConceptScore W2019196893C2779603750 @default.
• W2019196893 hasConceptScore W2019196893C32786932 @default.
• W2019196893 hasConceptScore W2019196893C43617362 @default.
• W2019196893 hasConceptScore W2019196893C486523 @default.
• W2019196893 hasConceptScore W2019196893C52859227 @default.
• W2019196893 hasConceptScore W2019196893C55493867 @default.
• W2019196893 hasConceptScore W2019196893C71240020 @default.
• W2019196893 hasLocation W20191968931 @default.
• W2019196893 hasLocation W20191968932 @default.
• W2019196893 hasOpenAccess W2019196893 @default.
• W2019196893 hasPrimaryLocation W20191968931 @default.
• W2019196893 hasRelatedWork W1986270771 @default.

• next