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- W2019215773 abstract "The protooncogene bcl-2 encodes a protein that inhibits apoptosis. The protein is expressed in most epithelial cells of the fetal thymic medulla but, to the best of our knowledge, no data are available on bcl-2 expression in thymoma. Expression of bcl-2 protein was analysed in 30 cases of thymoma by immunohistological staining of paraffin-embedded tissue. All cases were examined and classified according to the Salyer and Eggleston and the Müller-Hermelink classification. In four cases, the protooncogene bcl-2 was abnormally expressed in spindle cells of pure medullary thymoma, whereas the non-spindle cells in mixed and in cortical thymoma were negative. All the lymphocytes were also strongly positive in medullary thymoma while a few lymphocytes showed light staining in other thymomas." @default.
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- W2019215773 date "1995-09-01" @default.
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- W2019215773 title "Immunohistochemical detection of bcl-2 protein in thymoma" @default.
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- W2019215773 doi "https://doi.org/10.1111/j.1365-2559.1995.tb00217.x" @default.
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