Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019221997> ?p ?o ?g. }
- W2019221997 endingPage "96" @default.
- W2019221997 startingPage "89" @default.
- W2019221997 abstract "The objective of this study was production of nanostructured lipid carriers (NLC) of valproic acid for brain delivery thought the nasal pathway. NLC were prepared by solvent diffusion method using a Taguchi design. The lipid, oil and valproic acid were dissolved in organic phase then dispersed in aqueous phase containing the surfactant. The most effective factors on size were surfactant concentration, organic/aqueous phase ratio and acetone/ethanol volume ratio. Zeta potential was more affected by the lipid type, while the surfactant concentration and sonication time were more effective variables on drug release rate. The entrapment efficiency was more affected by lipid/drug weight ratio. Optimum formulation obtained with 400 mg lipid, 400 mg valproic acid, 2% surfactant, 1:5 organic/aqueous phase ratio, 1:1 acetone/ethanol volume ratio and 2 min sonication." @default.
- W2019221997 created "2016-06-24" @default.
- W2019221997 creator A5027690668 @default.
- W2019221997 creator A5051488320 @default.
- W2019221997 creator A5080481625 @default.
- W2019221997 date "2010-01-21" @default.
- W2019221997 modified "2023-10-01" @default.
- W2019221997 title "Production and optimization of valproic acid nanostructured lipid carriers by the Taguchi design" @default.
- W2019221997 cites W1579046626 @default.
- W2019221997 cites W1964026121 @default.
- W2019221997 cites W1968119282 @default.
- W2019221997 cites W1980310024 @default.
- W2019221997 cites W1981468523 @default.
- W2019221997 cites W1981609978 @default.
- W2019221997 cites W1984148393 @default.
- W2019221997 cites W1989359894 @default.
- W2019221997 cites W1991785356 @default.
- W2019221997 cites W1996779957 @default.
- W2019221997 cites W2002325311 @default.
- W2019221997 cites W2009338757 @default.
- W2019221997 cites W2014537537 @default.
- W2019221997 cites W2015879870 @default.
- W2019221997 cites W2016381215 @default.
- W2019221997 cites W2016599364 @default.
- W2019221997 cites W2018340655 @default.
- W2019221997 cites W2019355258 @default.
- W2019221997 cites W2020779982 @default.
- W2019221997 cites W2020975942 @default.
- W2019221997 cites W2028258807 @default.
- W2019221997 cites W2041016731 @default.
- W2019221997 cites W2044681516 @default.
- W2019221997 cites W2045000096 @default.
- W2019221997 cites W204512410 @default.
- W2019221997 cites W2046168735 @default.
- W2019221997 cites W2046414976 @default.
- W2019221997 cites W2048634673 @default.
- W2019221997 cites W2054189154 @default.
- W2019221997 cites W2056812747 @default.
- W2019221997 cites W2060111182 @default.
- W2019221997 cites W2061346349 @default.
- W2019221997 cites W2064384776 @default.
- W2019221997 cites W2071306094 @default.
- W2019221997 cites W2077978240 @default.
- W2019221997 cites W2082865634 @default.
- W2019221997 cites W2085756943 @default.
- W2019221997 cites W2100958444 @default.
- W2019221997 cites W2120833124 @default.
- W2019221997 cites W2141162588 @default.
- W2019221997 cites W2146408988 @default.
- W2019221997 cites W2155158412 @default.
- W2019221997 cites W2156878630 @default.
- W2019221997 doi "https://doi.org/10.3109/10837450903013568" @default.
- W2019221997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19552542" @default.
- W2019221997 hasPublicationYear "2010" @default.
- W2019221997 type Work @default.
- W2019221997 sameAs 2019221997 @default.
- W2019221997 citedByCount "66" @default.
- W2019221997 countsByYear W20192219972012 @default.
- W2019221997 countsByYear W20192219972013 @default.
- W2019221997 countsByYear W20192219972014 @default.
- W2019221997 countsByYear W20192219972015 @default.
- W2019221997 countsByYear W20192219972016 @default.
- W2019221997 countsByYear W20192219972017 @default.
- W2019221997 countsByYear W20192219972018 @default.
- W2019221997 countsByYear W20192219972019 @default.
- W2019221997 countsByYear W20192219972020 @default.
- W2019221997 countsByYear W20192219972021 @default.
- W2019221997 countsByYear W20192219972022 @default.
- W2019221997 countsByYear W20192219972023 @default.
- W2019221997 crossrefType "journal-article" @default.
- W2019221997 hasAuthorship W2019221997A5027690668 @default.
- W2019221997 hasAuthorship W2019221997A5051488320 @default.
- W2019221997 hasAuthorship W2019221997A5080481625 @default.
- W2019221997 hasConcept C104628117 @default.
- W2019221997 hasConcept C127413603 @default.
- W2019221997 hasConcept C144176778 @default.
- W2019221997 hasConcept C149556010 @default.
- W2019221997 hasConcept C155672457 @default.
- W2019221997 hasConcept C159985019 @default.
- W2019221997 hasConcept C169760540 @default.
- W2019221997 hasConcept C171250308 @default.
- W2019221997 hasConcept C178790620 @default.
- W2019221997 hasConcept C184651966 @default.
- W2019221997 hasConcept C185592680 @default.
- W2019221997 hasConcept C192562407 @default.
- W2019221997 hasConcept C2777172819 @default.
- W2019221997 hasConcept C2778186239 @default.
- W2019221997 hasConcept C2780471494 @default.
- W2019221997 hasConcept C2781213060 @default.
- W2019221997 hasConcept C42360764 @default.
- W2019221997 hasConcept C43617362 @default.
- W2019221997 hasConcept C55493867 @default.
- W2019221997 hasConcept C58226133 @default.
- W2019221997 hasConcept C83469408 @default.
- W2019221997 hasConcept C86181022 @default.
- W2019221997 hasConcept C86803240 @default.
- W2019221997 hasConceptScore W2019221997C104628117 @default.
- W2019221997 hasConceptScore W2019221997C127413603 @default.