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- W2019236479 abstract "We introduce a novel solid-phase colorimetric sensor facilely fabricated by loading unmodified gold nanoparticles into poly(oligo(ethylene glycol)methacrylate) (POEGMA) brushes grown on glass. Our work reports the first synergistic combination of metallic nanoparticles acting as a colorimetric sensing module with a nonfouling polymer matrix acting both as a nonrigid scaffold and a screen to reduce interference from nontarget molecules. In addition, as the nanocomposite is formed on a transparent substrate, solid-phase detection can be performed in the same manner as in the solution-phase. We demonstrate the use of this unique platform for label-free lead detection based on the release of gold nanoparticles from the polymer brush upon exposure to lead ions. An ultralow limit-of-detection of 25 pM (S/N = 3) and a dynamic range of 100 pM to 100 nM (R(2) = 0.987) are achieved. Furthermore, the detection is up to 1000-fold more selective to lead over other common heavy metal ions." @default.
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- W2019236479 date "2013-04-03" @default.
- W2019236479 modified "2023-10-02" @default.
- W2019236479 title "Solid-Phase Colorimetric Sensor Based on Gold Nanoparticle-Loaded Polymer Brushes: Lead Detection as a Case Study" @default.
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- W2019236479 doi "https://doi.org/10.1021/ac4001817" @default.
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