Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019250097> ?p ?o ?g. }
- W2019250097 endingPage "1647" @default.
- W2019250097 startingPage "1642" @default.
- W2019250097 abstract "The synthesis, photochemistry, and biological application of 1-acyl-5-methoxy-8-nitro-1,2-dihydroquinoline (MNDQ-caged carboxylic acid) are described. Optimization experiments were carried out on three acetyl derivatives (3a–c), and the most appropriate analogue for application to the caging of glutamate was determined to be 3c. Thus, a MNDQ-caged glutamate (MNDQ-Glu) was synthesized, and the photochemical release of glutamate by uncaging of MNDQ-Glu was confirmed by NMR, MS, and HPLC analysis. When MNDQ-Glu was tested with pyramidal neurons in hippocampal slices, whole-field UV illumination resulted in a large inward current due to the release of l-glutamate. A short two-photon uncaging of MNDQ-Glu at single dendritic spines induced a transient current that exhibited similar kinetic properties to miniature excitatory postsynaptic currents (mEPSC)." @default.
- W2019250097 created "2016-06-24" @default.
- W2019250097 creator A5017011235 @default.
- W2019250097 creator A5017331725 @default.
- W2019250097 creator A5040328741 @default.
- W2019250097 creator A5067627277 @default.
- W2019250097 creator A5070852791 @default.
- W2019250097 creator A5088226884 @default.
- W2019250097 date "2010-03-01" @default.
- W2019250097 modified "2023-10-12" @default.
- W2019250097 title "1-Acyl-5-methoxy-8-nitro-1,2-dihydroquinoline: a biologically useful photolabile precursor of carboxylic acids" @default.
- W2019250097 cites W1498196254 @default.
- W2019250097 cites W1798313689 @default.
- W2019250097 cites W1966776610 @default.
- W2019250097 cites W1969789910 @default.
- W2019250097 cites W1970322363 @default.
- W2019250097 cites W1971663166 @default.
- W2019250097 cites W1975169261 @default.
- W2019250097 cites W1975359280 @default.
- W2019250097 cites W1977541636 @default.
- W2019250097 cites W1983284219 @default.
- W2019250097 cites W1985928429 @default.
- W2019250097 cites W1993912247 @default.
- W2019250097 cites W2009248881 @default.
- W2019250097 cites W2014343167 @default.
- W2019250097 cites W2021840869 @default.
- W2019250097 cites W2022243850 @default.
- W2019250097 cites W2025395772 @default.
- W2019250097 cites W2025798657 @default.
- W2019250097 cites W2029080131 @default.
- W2019250097 cites W2039020311 @default.
- W2019250097 cites W2039553498 @default.
- W2019250097 cites W2043288620 @default.
- W2019250097 cites W2043932860 @default.
- W2019250097 cites W2044954908 @default.
- W2019250097 cites W2051966283 @default.
- W2019250097 cites W2062455334 @default.
- W2019250097 cites W2062969241 @default.
- W2019250097 cites W2068856408 @default.
- W2019250097 cites W2072821537 @default.
- W2019250097 cites W2075874770 @default.
- W2019250097 cites W2076809828 @default.
- W2019250097 cites W2087693629 @default.
- W2019250097 cites W2092435369 @default.
- W2019250097 cites W2103443238 @default.
- W2019250097 cites W2109399781 @default.
- W2019250097 cites W2113231837 @default.
- W2019250097 cites W2113977236 @default.
- W2019250097 cites W2132082655 @default.
- W2019250097 cites W2138116587 @default.
- W2019250097 cites W2139149324 @default.
- W2019250097 cites W2144610655 @default.
- W2019250097 cites W2154997867 @default.
- W2019250097 cites W2168109878 @default.
- W2019250097 cites W2169873791 @default.
- W2019250097 cites W4243207808 @default.
- W2019250097 cites W4253562377 @default.
- W2019250097 doi "https://doi.org/10.1016/j.tetlet.2009.12.081" @default.
- W2019250097 hasPublicationYear "2010" @default.
- W2019250097 type Work @default.
- W2019250097 sameAs 2019250097 @default.
- W2019250097 citedByCount "12" @default.
- W2019250097 countsByYear W20192500972012 @default.
- W2019250097 countsByYear W20192500972013 @default.
- W2019250097 countsByYear W20192500972014 @default.
- W2019250097 countsByYear W20192500972016 @default.
- W2019250097 crossrefType "journal-article" @default.
- W2019250097 hasAuthorship W2019250097A5017011235 @default.
- W2019250097 hasAuthorship W2019250097A5017331725 @default.
- W2019250097 hasAuthorship W2019250097A5040328741 @default.
- W2019250097 hasAuthorship W2019250097A5067627277 @default.
- W2019250097 hasAuthorship W2019250097A5070852791 @default.
- W2019250097 hasAuthorship W2019250097A5088226884 @default.
- W2019250097 hasBestOaLocation W20192500971 @default.
- W2019250097 hasConcept C112592302 @default.
- W2019250097 hasConcept C170493617 @default.
- W2019250097 hasConcept C178790620 @default.
- W2019250097 hasConcept C185592680 @default.
- W2019250097 hasConcept C197341189 @default.
- W2019250097 hasConcept C2780263894 @default.
- W2019250097 hasConcept C2780554229 @default.
- W2019250097 hasConcept C2780639532 @default.
- W2019250097 hasConcept C55493867 @default.
- W2019250097 hasConcept C61174792 @default.
- W2019250097 hasConceptScore W2019250097C112592302 @default.
- W2019250097 hasConceptScore W2019250097C170493617 @default.
- W2019250097 hasConceptScore W2019250097C178790620 @default.
- W2019250097 hasConceptScore W2019250097C185592680 @default.
- W2019250097 hasConceptScore W2019250097C197341189 @default.
- W2019250097 hasConceptScore W2019250097C2780263894 @default.
- W2019250097 hasConceptScore W2019250097C2780554229 @default.
- W2019250097 hasConceptScore W2019250097C2780639532 @default.
- W2019250097 hasConceptScore W2019250097C55493867 @default.
- W2019250097 hasConceptScore W2019250097C61174792 @default.
- W2019250097 hasIssue "13" @default.
- W2019250097 hasLocation W20192500971 @default.
- W2019250097 hasOpenAccess W2019250097 @default.
- W2019250097 hasPrimaryLocation W20192500971 @default.