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- W2019268124 abstract "A controlled case study of a severely hyperactive, moderately retarded 4-year-old boy was conducted in which the efficacy of methylphenidate, fenfluramine, and placebo was assessed. Four separate placebo-controlled evaluations were conducted over a 2.5 year period. Initially, methylphenidate was clinically effective in decreasing overactivity; however, it was later shown to exacerbate the child's symptoms. In a subsequent drug evaluation, flenfluramine was found to produce dramatic behavioral improvement. Procedures for and difficulties with assessing drug response in this patient population are discussed." @default.
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- W2019268124 title "A controlled case study of methylphenidate and fenfluramine in a young mentally retarded, hyperactive child" @default.
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