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- W2019303630 abstract "The hydroformylation of 2-phenyl-4-(prop-2-enyl)[1,3]dioxanes has been studied. anti-Acetals1a,b were found to give extraordinarily high diastereoselectivity on hydroformylation, giving rise to the formation of the all-anti stereotriades 2a,b. The origin of this stereoselectivity may be related to the preferred conformation of the actetals 3 in solution, as determined by 2D-NOESY NMR experiments and force field calculations (MM3). Hydroformylation of 1a afforded an intermediate for a short and efficient synthesis of a key building block for the total synthesis of the macrolide antibiotic bafilomycin A1." @default.
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- W2019303630 date "1998-04-01" @default.
- W2019303630 modified "2023-10-12" @default.
- W2019303630 title "Diastereoselective hydroformylation of acyclic olefins: Efficient construction of an all-anti stereotriade building block for polyketide synthesis" @default.
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