Matches in SemOpenAlex for { <https://semopenalex.org/work/W2019316253> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2019316253 endingPage "180" @default.
- W2019316253 startingPage "175" @default.
- W2019316253 abstract "Trois nouveaux herpesvirus humains ont été découverts récemment : l'herpesvirus humain 6 (HHV-6) en 1986, l'herpesvirus humain 7 (HHV-7) en 1990 et l'herpesvirus humain 8 (HHV-8) en 1994. Le HHV-6 et le HHV-7 ont été isolés pour la première fois en cultures de lymphocytes alors que le HHV-8 a été identifié par une approche moléculaire menée à la recherche de l'agent étiologique de la maladie de Kaposi. Les trois virus infectent les lymphocytes, les lymphocytes T pour le HHV-6 et le HHV-7, les lymphocytes B pour le HHV-8. Les infections à HHV-6 et HHV-7 sont extrêmement répandues dans la population mondiale alors que l'infection à HHV-8 suit un gradient de fréquence décroissant de l'Europe du Nord vers le centre de l'Afrique. L'amplification génique (PCR) est la méthode la plus accessible pour détecter et caractériser génétiquement ces virus dans les échantillons biologiques. Le rôle pathogène du HHV-6 et du HHV-7, tous deux classés dans la sous-famille des Betaherpesvirinae, parait modeste : le HHV-6 est l'agent de l'exanthème subit et serait impliqué dans des infections opportunistes; une association entre le HHV-7 et le pityriasis rosé de Gibert a été rapportée mais non confirmée. Le HHV-8, classé parmi les Gammaherpesvirinae, paraît très impliqué dans trois maladies comportant une prolifération du tissu lymphoide: la maladie de Kaposi, la maladie de Castleman et les lymphomes primitifs des séreuses. Three novel human herpesviruses have been discovered recently: human herpesvirus 6 (HHV-6) in 1986, human herpesvirus 7 (HHV-7) in 1990, human herpesvirus 8 (HHV8) in 1994. HHV-6 and HHV-7 were identified after their isolation from blood lymphocyte cultures, while HHV-8 was first detected by means of a specific molecular biology approach in the search for the etiologic agent of Kaposi's sarcoma. The three viruses infect lymphocytes, T-cells in the case of HHV-6 and HHV-7, B-cells in the case of HHV-8. Human infection with HHV-6 and HHV-7 is ubiquitous and widespread while the frequency of HHV-8 infection increases starting from Northern Europe to the centre of Africa. The polymerase chain reaction is the commonest method for the detection of these three viruses in human samples. The pathogenic role of HHV-6 and HHV-7 which were both classified in Betaherpesvirinae subfamily is modest: HHV-6 is the causative agent of exanthem subitum and opportunistic infections; an association between HHV-7 and pityriasis rosea has been reported but requires confirmation. HHV-8, classified as a member of Gammaherpesvirinae subfamily, is strongly associated with three lymphoproliferative diseases: Kaposi's sarcoma, Castleman's disease and primary effusion lymphomas." @default.
- W2019316253 created "2016-06-24" @default.
- W2019316253 creator A5012558883 @default.
- W2019316253 creator A5026234029 @default.
- W2019316253 creator A5050578528 @default.
- W2019316253 creator A5060063338 @default.
- W2019316253 creator A5084209829 @default.
- W2019316253 date "1999-05-01" @default.
- W2019316253 modified "2023-09-26" @default.
- W2019316253 title "Les nouveaux herpesvirus lymphotropes humains: les herpesvirus humains 6, 7 et 8" @default.
- W2019316253 cites W1534625428 @default.
- W2019316253 cites W1786775693 @default.
- W2019316253 cites W1963829537 @default.
- W2019316253 cites W1970339166 @default.
- W2019316253 cites W1972299382 @default.
- W2019316253 cites W1980647423 @default.
- W2019316253 cites W1986097409 @default.
- W2019316253 cites W2000147682 @default.
- W2019316253 cites W2000603287 @default.
- W2019316253 cites W2005812973 @default.
- W2019316253 cites W2009498709 @default.
- W2019316253 cites W2010279858 @default.
- W2019316253 cites W2017324951 @default.
- W2019316253 cites W2018669122 @default.
- W2019316253 cites W2028318125 @default.
- W2019316253 cites W2028840705 @default.
- W2019316253 cites W2029374310 @default.
- W2019316253 cites W2031522803 @default.
- W2019316253 cites W2031891917 @default.
- W2019316253 cites W2032438721 @default.
- W2019316253 cites W2034806350 @default.
- W2019316253 cites W2035092384 @default.
- W2019316253 cites W2035612469 @default.
- W2019316253 cites W2043892841 @default.
- W2019316253 cites W2046119263 @default.
- W2019316253 cites W2053246464 @default.
- W2019316253 cites W2062227071 @default.
- W2019316253 cites W2068530876 @default.
- W2019316253 cites W2070335382 @default.
- W2019316253 cites W2081651119 @default.
- W2019316253 cites W2089178114 @default.
- W2019316253 cites W2094583360 @default.
- W2019316253 cites W2105033060 @default.
- W2019316253 cites W2115396398 @default.
- W2019316253 cites W2159163386 @default.
- W2019316253 cites W2312580646 @default.
- W2019316253 cites W2327671886 @default.
- W2019316253 cites W2329104334 @default.
- W2019316253 cites W2336241188 @default.
- W2019316253 cites W2409241250 @default.
- W2019316253 cites W2410723119 @default.
- W2019316253 cites W3146308493 @default.
- W2019316253 doi "https://doi.org/10.1016/s0923-2532(99)80047-7" @default.
- W2019316253 hasPublicationYear "1999" @default.
- W2019316253 type Work @default.
- W2019316253 sameAs 2019316253 @default.
- W2019316253 citedByCount "0" @default.
- W2019316253 crossrefType "journal-article" @default.
- W2019316253 hasAuthorship W2019316253A5012558883 @default.
- W2019316253 hasAuthorship W2019316253A5026234029 @default.
- W2019316253 hasAuthorship W2019316253A5050578528 @default.
- W2019316253 hasAuthorship W2019316253A5060063338 @default.
- W2019316253 hasAuthorship W2019316253A5084209829 @default.
- W2019316253 hasConcept C153911025 @default.
- W2019316253 hasConcept C159047783 @default.
- W2019316253 hasConcept C2522874641 @default.
- W2019316253 hasConcept C3018958071 @default.
- W2019316253 hasConcept C86803240 @default.
- W2019316253 hasConceptScore W2019316253C153911025 @default.
- W2019316253 hasConceptScore W2019316253C159047783 @default.
- W2019316253 hasConceptScore W2019316253C2522874641 @default.
- W2019316253 hasConceptScore W2019316253C3018958071 @default.
- W2019316253 hasConceptScore W2019316253C86803240 @default.
- W2019316253 hasIssue "3" @default.
- W2019316253 hasLocation W20193162531 @default.
- W2019316253 hasOpenAccess W2019316253 @default.
- W2019316253 hasPrimaryLocation W20193162531 @default.
- W2019316253 hasVolume "14" @default.
- W2019316253 isParatext "false" @default.
- W2019316253 isRetracted "false" @default.
- W2019316253 magId "2019316253" @default.
- W2019316253 workType "article" @default.